Biomarkers intersect with the exposome

The exposome: from concept to utility

(2012) Christopher Paul Wild   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Stitching together Multiple Data Dimensions Reveals Interacting Metabolomic and Transcriptomic Networks That Modulate Cell Regulation

(2012) Jun Zhu et al.   PLOS BIOLOGY

Status and Prospects for Discovery and Verification of New Biomarkers of Cardiovascular Disease by Proteomics

(2011) Robert E. Gerszten et al.   CIRCULATION RESEARCH

Epidemiology, epigenetics and the ‘Gloomy Prospect’: embracing randomness in population health research and practice

(2011) George Davey Smith   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Metabolomics, Pathway Regulation, and Pathway Discovery

(2011) Guo-Fang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human serum-derived hydroxy long-chain fatty acids exhibit anti-inflammatory and anti-proliferative activity

(2011) Shawn A Ritchie et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Advances in top-down proteomics for disease biomarker discovery

(2011) David Calligaris et al.   Journal of Proteomics

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

(2011) Zeneng Wang et al.   NATURE

Metabolite profiles and the risk of developing diabetes

(2011) Thomas J Wang et al.   NATURE MEDICINE

Metabolomics as a tool for cardiac research

(2011) Julian L. Griffin et al.   Nature Reviews Cardiology

Emerging molecular biomarkers—blood-based strategies to detect and monitor cancer

(2011) Samir M. Hanash et al.   Nature Reviews Clinical Oncology

Genome-wide transcription factor binding: beyond direct target regulation

(2011) Kyle L. MacQuarrie et al.   TRENDS IN GENETICS

Targeted Metabolomics for Biomarker Discovery

(2010) William J. Griffiths et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Reduction of novel circulating long-chain fatty acids in colorectal cancer patients is independent of tumor burden and correlates with age

(2010) Shawn A Ritchie et al.   BMC GASTROENTEROLOGY

Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection

(2010) Shawn A Ritchie et al.   BMC Medicine

Applications of liquid chromatography coupled to mass spectrometry-based metabolomics in clinical chemistry and toxicology: A review

(2010) Aurélie Roux et al.   CLINICAL BIOCHEMISTRY

Implications of the exposome for exposure science

(2010) Stephen M Rappaport   Journal of Exposure Science and Environmental Epidemiology

Glycomic and Glycoproteomic Analysis of Serum from Patients with Stomach Cancer Reveals Potential Markers Arising from Host Defense Response Mechanisms

(2010) Jonathan Bones et al.   JOURNAL OF PROTEOME RESEARCH

Profiling Cys34Adducts of Human Serum Albumin by Fixed-Step Selected Reaction Monitoring

(2010) He Li et al.   MOLECULAR & CELLULAR PROTEOMICS

Gene–environment-wide association studies: emerging approaches

(2010) Duncan Thomas   NATURE REVIEWS GENETICS

Viral hepatocarcinogenesis

(2010) W-L Tsai et al.   ONCOGENE

An Environment-Wide Association Study (EWAS) on Type 2 Diabetes Mellitus

(2010) Chirag J. Patel et al.   PLoS One

Environment and Disease Risks

(2010) S. M. Rappaport et al.   SCIENCE

From differentiating metabolites to biomarkers

(2009) Albert Koulman et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Silent myocardial ischemia is associated with altered plasma phospholipids

(2009) Hailong Lin et al.   JOURNAL OF CLINICAL LABORATORY ANALYSIS

Metabolomics: Moving to the Clinic

(2009) Anders Nordström et al.   Journal of Neuroimmune Pharmacology

Common Genetic Variation and Human Traits

(2009) David B. Goldstein   NEW ENGLAND JOURNAL OF MEDICINE

Potential etiologic and functional implications of genome-wide association loci for human diseases and traits

(2009) L. A. Hindorff et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabonomic profiling of renal cell carcinoma: High-resolution proton nuclear magnetic resonance spectroscopy of human serum with multivariate data analysis

(2008) Hongchang Gao et al.   ANALYTICA CHIMICA ACTA

A new rule-based algorithm for identifying metabolic markers in prostate cancer using tandem mass spectrometry

(2008) M. Osl et al.   BIOINFORMATICS

Metabolomic profiling to develop blood biomarkers for Parkinson's disease

(2008) M. Bogdanov et al.   BRAIN

Metabolic Phenotyping in Health and Disease

(2008) Elaine Holmes et al.   CELL

Clinical utility of drug measurement and pharmacokinetics – therapeutic drug monitoring in psychiatry

(2008) Christoph Hiemke   EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY

Multiple reaction monitoring for quantitative biomarker analysis in proteomics and metabolomics☆

(2008) Neil R. Kitteringham et al.   JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES

Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury

(2008) Gregory D. Lewis et al.   JOURNAL OF CLINICAL INVESTIGATION

The Metabonomic Signature of Celiac Disease

(2008) Ivano Bertini et al.   JOURNAL OF PROTEOME RESEARCH

Nuclear magnetic resonance-based metabolomics predicts exercise-induced ischemia in patients with suspected coronary artery disease

(2008) Ignasi Barba et al.   MAGNETIC RESONANCE IN MEDICINE

Human metabolic phenotype diversity and its association with diet and blood pressure

(2008) Elaine Holmes et al.   NATURE

The search for new cardiovascular biomarkers

(2008) Robert E. Gerszten et al.   NATURE

Mining the plasma proteome for cancer biomarkers

(2008) Samir M. Hanash et al.   NATURE

The environmental contribution to gene expression profiles

(2008) Greg Gibson   NATURE REVIEWS GENETICS

General and Abdominal Adiposity and Risk of Death in Europe

(2008) T. Pischon et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protein Damage by Reactive Electrophiles: Targets and Consequences

(2007) Daniel C. Liebler   CHEMICAL RESEARCH IN TOXICOLOGY