Journal
BIOMARKERS
Volume 17, Issue 1, Pages 85-95Publisher
TAYLOR & FRANCIS LTD
DOI: 10.3109/1354750X.2011.639464
Keywords
Pacific oyster; metallothionein; susceptibility; genotypes; selection
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Funding
- Bureau des Ressources Genetiques [02-2-500022, 05/5210 460/YF]
- Marine Genomics Europe Network
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Summer mortality events have been observed in Pacific oyster Crassostrea gigas for several decades. This paper examines the selective pressure exerted by summer mortality on the polymorphism of a newly identified oyster metallothionein gene. CgMT4 cDNA and genomic sequences were obtained. CgMT4 was studied in two generations of oysters reared in three sites on the French Atlantic coast, using single strand conformation polymorphism analysis. Four alleles were detected. Individuals carrying genotype MT4-CD seem to have higher susceptibility to summer risk conditions. The MT4 gene could be a potential new genetic marker for susceptibility; further validation studies are recommended.
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