Article
Cardiac & Cardiovascular Systems
Samuel K. Sorensen, Arne Johannessen, Rene Worck, Morten L. Hansen, Jim Hansen
Summary: Radiofrequency and cryoballoon catheter ablation demonstrate similar moderate to high durability in pulmonary vein isolation. However, about 5% of patients experienced recurrence of atrial fibrillation despite complete and durable PVI. The reduction in AF burden is associated with the number of durably isolated pulmonary veins.
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Jonas Woermann, Jakob Lueker, Jan-Hendrik van den Bruck, Karlo Filipovic, Susanne Erlhoefer, Cornelia Scheurlen, Sebastian Dittrich, Jan-Hendrik Schipper, Daniel Steven, Arian Sultan
Summary: This study compared the efficacy and procedural differences between high power short duration radiofrequency ablation (HPSD) and cryoballoon ablation (CB) in the treatment of atrial fibrillation. The results showed that HPSD and CB had similar success rates and safety profiles, but HPSD had a longer procedure duration. In conclusion, HPSD is a feasible and effective option for the ablation treatment of atrial fibrillation.
CLINICAL RESEARCH IN CARDIOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
J. Pongratz, L. Riess, S. Hartl, B. Brueck, C. Tesche, U. Ebersberger, T. Helmberger, A. Crispin, M. Wankerl, U. Dorwarth, E. Hoffmann, F. Straube
Summary: In patients with persistent atrial fibrillation (AF) undergoing cryoballoon ablation, the volume of the left atrial appendage (LAA) and the severity of mitral regurgitation were identified as independent predictors for arrhythmia recurrence.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Cardiac & Cardiovascular Systems
Dhiraj Gupta, Wern Yew Ding, Peter Calvert, Emmanuel Williams, Moloy Das, Lilith Tovmassian, Muzahir H. Tayebjee, Guy Haywood, Claire A. Martin, Kim Rajappan, Matthew G. D. Bates, Ian Peter Temple, Tobias Reichlin, Zhong Chen, Richard N. Balasubramaniam, Christina Ronayne, Nichola Clarkson, Maureen Morgan, Janet Barton, Ian Kemp, Saagar Mahida, Christian Sticherling
Summary: The study compared cryoballoon pulmonary vein isolation (PVI) with standard radiofrequency cavotricuspid isthmus (CTI) ablation for the first-line treatment of typical atrial flutter (AFL). The results showed that cryoballoon PVI was equally effective as CTI ablation in preventing the recurrence of atrial arrhythmia and better at preventing new-onset atrial fibrillation (AF).
Article
Medicine, General & Internal
Julian Mueller, Karin Nentwich, Artur Berkovitz, Kai Sonne, Olena Kozlova, Sebastian Barth, Alexandru Deacanu, Christian Waechter, Philipp Halbfass, Heiko Lehrmann, Thomas Deneke
Summary: This study investigated the characteristics of patients undergoing redo AF ablation and the impact of different ablation strategies. The results showed that pulmonary vein reconnection was common among all techniques of AF ablation, and different ablation strategies did not improve long-term success.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Medicine, General & Internal
Charlotte Eitel, Vanessa Sciacca, Nina Bartels, Roza Saraei, Thomas Fink, Ahmad Keelani, Andre Gassmann, Karl-Heinz Kuck, Julia Vogler, Christian-Hendrik Heeger, Roland Richard Tilz
Summary: This study analyzed the safety and efficacy of cryoballoon-based pulmonary vein isolation (CB-PVI) for symptomatic AF in patients with past or present cancer disease. The results showed that the frequency of complications and arrhythmia-free survival after 12 months did not significantly differ between patients with and without a history of cancer. Therefore, CB-PVI for symptomatic AF is equally safe and effective in patients with and without a history of cancer.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Lara Wagner, Fabrice F. Darche, Dierk Thomas, Patrick Lugenbiel, Panagiotis Xynogalos, Svenja Seide, Eberhard P. Scholz, Hugo A. Katus, Patrick A. Schweizer
Summary: Background modulation of the cardiac autonomic nervous system by pulmonary vein isolation (PVI) influences the sinoatrial nodal rate. Cryo-PVI causes a significant rise of sinus rate that is more pronounced in subjects with previous sinus bradycardia, with an increased risk of AF recurrence in patients with postprocedural bradycardia.
CLINICAL RESEARCH IN CARDIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Hanjin Park, Je-Wook Park, Daehoon Kim, Hee Tae Yu, Tae-Hoon Kim, Jae-Sun Uhm, Boyoung Joung, Moon-Hyoung Lee, Chun Hwang, Hui-Nam Pak
Summary: This study compared the efficacy and safety of cryoballoon, high-power short-duration, and conventional radiofrequency ablation in treating atrial fibrillation. The results showed that the Cryo-PVI group had similar major complication and clinical recurrence rates compared to the other groups. However, the Cryo-PVI group had a lower risk of recurrent AF in patients with paroxysmal AF and a higher risk in patients with persistent AF. Additionally, the Cryo-PVI group had higher post-procedural sympathetic nervous activity and sympatho-vagal balance compared to the conventional-PVI group.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2023)
Article
Medicine, General & Internal
Yun Young Choi, Jaemin Shim, Yun Gi Kim, Kyongjin Min, Seung-Young Roh, Jin Seok Kim, Jong-Il Choi, Young-Hoon Kim
Summary: Adenosine-induced atrial fibrillation (AIAF) does not affect the long-term recurrence rate after pulmonary vein isolation (PVI). Additional ablation for the trigger site of AIAF does not improve clinical outcomes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Arash Aryana, Shelley L. Allen, Deep K. Pujara, Mark R. Bowers, Padraig Gearoid O'Neill, Yasuteru Yamauchi, Takatoshi Shigeta, Eleanor C. Vierra, Kaoru Okishige, Andrea Natale
Summary: This study prospectively evaluated the short- and long-term outcomes of PVI versus PVI+PWI using the cryoballoon in patients with P/LSP-AF, finding a significant reduction in atrial fibrillation recurrence at 12 months with PVI+PWI, while showing similar safety compared to PVI alone.
JACC-CLINICAL ELECTROPHYSIOLOGY
(2021)
Article
Cardiac & Cardiovascular Systems
Chi Cai, Jing Wang, Hong-Xia Niu, Jian-Min Chu, Wei Hua, Shu Zhang, Yan Yao
Summary: This study investigates the association between lesion size index (LSI) and acute conduction gap formation during high-power (HP) ablation for pulmonary vein isolation (PVI) in atrial fibrillation (AF) patients. Using LSI-guided HP ablation, a LSI value above 4.35 for all PV segments showed the best predictive value in avoiding gap formation for effective first-pass PVI. The optimal LSI cutoff values for predicting gap formation were 4.55 for the anterior wall and 3.95 for the posterior wall.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2022)
Article
Medicine, General & Internal
Oussama M. Wazni, Gopi Dandamudi, Nitesh Sood, Robert Hoyt, Jaret Tyler, Sarfraz Durrani, Mark Niebauer, Kevin Makati, Blair Halperin, Andre Gauri, Gustavo Morales, Mingyuan Shao, Jeffrey Cerkvenik, Rachelle E. Kaplon, Steven E. Nissen
Summary: In this multicenter trial, cryoballoon ablation as initial therapy was found to be superior to drug therapy in preventing atrial arrhythmia recurrence in patients with paroxysmal atrial fibrillation. Serious procedure-related adverse events were uncommon.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Article
Cardiac & Cardiovascular Systems
Shohreh Honarbakhsh, Mark J. Earley, Claire A. Martin, Antonio Creta, Afzal Sohaib, Richard Ang, Charles Butcher, Peter H. Waddingham, Mehul Dhinoja, Wei Lim, Neil T. Srinivasan, Rui Providencia, Vijayabharathy Kanthasamy, Simon Sporton, Anthony Chow, Pier D. Lambiase, Richard J. Schilling, Malcolm C. Finlay, Ross J. Hunter
Summary: This study evaluated the use of the novel PolarX Cryoballoon in atrial fibrillation catheter ablation and compared it with the Arctic Front Advance. The results showed that the efficacy and safety of the PolarX Cryoballoon were comparable to the AFA Cryoballoon, but there were significant differences in cryoablation metrics.
Article
Cardiac & Cardiovascular Systems
Michael Kuhne, Sven Knecht, Florian Spies, Stefanie Aeschbacher, Philip Haaf, Michael Zellweger, Beat Schaer, Stefan Osswald, Christian Sticherling
Summary: The study showed that performing pulmonary vein isolation without demonstrating vein occlusion is feasible, reduces radiation exposure, and increases procedural efficiency.
FRONTIERS IN CARDIOVASCULAR MEDICINE
(2021)
Article
Medicine, General & Internal
Ana Isabel Molina-Ramos, Amalio Ruiz-Salas, Carmen Medina-Palomo, Francisco Javier Pavon-Moron, Jorge Rodriguez-Capitan, Mario Gutierrez-Bedmar, German Berteli-Garcia, Ignacio Fernandez-Lozano, Juan Jose Gomez-Doblas, Manuel Jimenez-Navarro, Javier Alzueta-Rodriguez, Alberto Barrera-Cordero
Summary: This study compared cryoballoon ablation and radiofrequency ablation in terms of their efficacy after the first procedure. The results showed that cryoballoon ablation had a lower need for reablation and a lower rate of pulmonary vein reconnection during follow-up.
JOURNAL OF CLINICAL MEDICINE
(2022)
Review
Cardiac & Cardiovascular Systems
Antonio Creta, Anthony W. Chow, Simon Sporton, Malcolm Finlay, Nikolaos Papageorgiou, Shohreh Honarbakhsh, Gurpreet Dhillon, Adam Graham, Kiran H. K. Patel, Mehul Dhinoja, Mark J. Earley, Ross J. Hunter, Martin Lowe, Edward Rowland, Oliver R. Segal, Vito Calabrese, Danilo Ricciardi, Pier D. Lambiase, Richard J. Schilling, Rui Providencia
INTERNATIONAL JOURNAL OF CARDIOLOGY
(2019)
Article
Cardiac & Cardiovascular Systems
Shohreh Honarbakhsh, Ross J. Hunter, Malcolm Finlay, Waqas Ullah, Emily Keating, Andrew Tinker, Richard J. Schilling
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2019)
Letter
Cardiac & Cardiovascular Systems
Antonio Creta, Rui Providencia, Malcolm Finlay
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2019)
Article
Cell Biology
Alison M. Thomas, Claudia P. Cabrera, Malcolm Finlay, Kulvinder Lall, Muriel Nobles, Richard J. Schilling, Kristie Wood, Charles A. Mein, Michael R. Barnes, Patricia B. Munroe, Andrew Tinker
PHYSIOLOGICAL GENOMICS
(2019)
Article
Cardiac & Cardiovascular Systems
Michele Orini, Adam J. Graham, Neil T. Srinivasan, Fernando O. Campos, Ben M. Hanson, Anthony Chow, Ross J. Hunter, Richard J. Schilling, Malcolm Finlay, Mark J. Earley, Simon Sporton, Mehul Dhinoja, Martin Lowe, Bradley Porter, Nicholas Child, Christopher A. Rinaldi, Jaswinder Gill, Martin Bishop, Peter Taggart, Pier D. Lambiase
Article
Cardiac & Cardiovascular Systems
Antonio Creta, Rui Providencia, Pedro Adragao, Carlo de Asmundis, Julian Chun, Gianbattista Chierchia, Pascal Defaye, Boris Schmidt, Frederic Anselme, Malcolm Finlay, Ross Jacob Hunter, Nikolaos Papageorgiou, Pier David Lambiase, Richard John Schilling, Stephane Combes, Nicolas Combes, Jean-Paul Albenque, Paolo Pozzilli, Serge Boveda
AMERICAN JOURNAL OF CARDIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Adam J. Graham, Michele Orini, Ernesto Zacur, Gurpreet Dhillon, Holly Daw, Neil T. Srinivasan, Claire Martin, Jem Lane, Josephine S. Mansell, Alex Cambridge, Jason Garcia, Francesca Pugliese, Oliver Segal, Syed Ahsan, Martin Lowe, Malcolm Finlay, Mark J. Earley, Anthony Chow, Simon Sporton, Mehul Dhinoja, Ross J. Hunter, Richard J. Schilling, Pier D. Lambiase
CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY
(2020)
Article
Cardiac & Cardiovascular Systems
Vinit Sawhney, Richard J. Schilling, Rui Providencia, Matthew Cadd, Dhanuka Perera, Salman Chatha, Ben Mercer, Malcolm Finlay, Franck Halimi, Dominique Pavin, Frederic Anselme, Jean-Pierre Cebron, Jongi Chun, Boris Schmidt, Pascal Defaye, Gurpreet Dhillon, Serge Boveda, Jean-Paul Albenque, Muzahir Tayebjee, Carlo de Asmundis, Gianbattista Chierchia, Ross J. Hunter
Article
Cardiac & Cardiovascular Systems
Gurpreet S. Dhillon, Richard J. Schilling, Shohreh Honarbakhsh, Adam Graham, Hakam Abbass, Peter Waddingham, Vinit Sawhney, Antonio Creta, Simon Sporton, Malcolm Finlay, Rui Providencia, Anthony Chow, Mark J. Earley, Martin Lowe, Pier D. Lambiase, Ross J. Hunter
JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY
(2020)
Review
Hematology
Antonio Creta, Malcolm Finlay, Ross J. Hunter, Anthony Chow, Simon Sporton, Amal Muthumala, Gurpreet Dhillon, Nikolaos Papageorgiou, Peter Waddingham, Syed Ahsan, Mehul Dhinoja, Mark J. Earley, Fakhar Khan, Martin Lowe, Mahmood Ahmad, Danilo Ricciardi, Francesco Grigioni, Germano Di Sciascio, Pier D. Lambiase, Richard J. Schilling, Rui Providencia
THROMBOSIS RESEARCH
(2020)
Editorial Material
Cardiac & Cardiovascular Systems
Vijayabharathy Kanthasamy, Malcolm Finlay
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2021)
Article
Neurosciences
Nikhil Ahluwalia, Adam Graham, Shohreh Honarbakhsh, Tillana Tarkas, Samuel Martin, Chris Monkhouse, Malcolm Finlay, Mark J. Earley, Roser Icart, Oliver Spooner, Arvind Chandratheva, Richard J. Schilling
Summary: This study evaluated the efficacy of implantable loop recorders (ILRs) in diagnosing atrial fibrillation (AF) in patients following Cryptogenic stroke (CS). The results showed that, despite late implantation, the ILR-based AF detection rate was high among referred CS patients. Age and CHA(2)DS(2)-VASc score were positively correlated with AF detection.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2022)
Article
Cardiac & Cardiovascular Systems
Jonathan M. Behar, Malcolm C. Finlay, Edward Rowland, Vivienne Ezzat, Simon Sporton, Mehul Dhinoja
EUROPEAN HEART JOURNAL-CASE REPORTS
(2020)
Letter
Cardiac & Cardiovascular Systems
Maniragav Manimaran, Debashish Das, Paula Martinez, Rhona Schwartz, Richard Schilling, Malcolm Finlay
EUROPEAN HEART JOURNAL-QUALITY OF CARE AND CLINICAL OUTCOMES
(2019)
Article
Cardiac & Cardiovascular Systems
Shohreh Honarbakhsh, Ross J. Hunter, Waqas Ullah, Emily Keating, Malcolm Finlay, Richard J. Schilling
JACC-CLINICAL ELECTROPHYSIOLOGY
(2019)