Male Mice Produced by In Vitro Culture Have Reduced Fertility and Transmit Organomegaly and Glucose Intolerance to Their Male Offspring1

A third component causing random variability beside environment and genotype. A reason for the limited success of a 30 year long effort to standardize laboratory animals?1,2

(2012) Klaus Gärtner   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Microinjection Manipulation Resulted in the Increased Apoptosis of Spermatocytes in Testes from Intracytoplasmic Sperm Injection (ICSI) Derived Mice

(2011) Yang Yu et al.   PLoS One

Transcriptional sexual dimorphism in elongating bovine embryos: implications for XCI and sex determination genes

(2011) P Bermejo-Alvarez et al.   REPRODUCTION

Long-term and transgenerational effects of in vitro culture on mouse embryos

(2011) Alexandra Calle et al.   THERIOGENOLOGY

Histone Modifications at the Blastocyst Axin1Fu Locus Mark the Heritability of In Vitro Culture-Induced Epigenetic Alterations in Mice1

(2010) Raul Fernandez-Gonzalez et al.   BIOLOGY OF REPRODUCTION

Glucose Parameters Are Altered in Mouse Offspring Produced by Assisted Reproductive Technologies and Somatic Cell Nuclear Transfer1

(2010) Karen A. Scott et al.   BIOLOGY OF REPRODUCTION

Upregulation of Bcl2 inhibits apoptosis-driven BAX insertion but favors BAX relocalization in mitochondria

(2010) O. Teijido et al.   FEBS LETTERS

Gadd45b Mediates Fas-induced Apoptosis by Enhancing the Interaction between p38 and Retinoblastoma Tumor Suppressor

(2010) Hee Jun Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Allele-specific expression of the MAOA gene and X chromosome inactivation in in vitro produced bovine embryos

(2010) A.R. Ferreira et al.   MOLECULAR REPRODUCTION AND DEVELOPMENT

KAP1 controls endogenous retroviruses in embryonic stem cells

(2010) Helen M. Rowe et al.   NATURE

Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts

(2010) P. Bermejo-Alvarez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reduced levels of two modifiers of epigenetic gene silencing, Dnmt3a and Trim28, cause increased phenotypic noise

(2010) Nadia C Whitelaw et al.   GENOME BIOLOGY

Effect of Stem Cell Activation, Culture Media of Manipulated Embryos, and Site of Embryo Transfer in the Production of F0 Embryonic Stem Cell Mice1

(2009) Miguel Angel Ramírez et al.   BIOLOGY OF REPRODUCTION

Endonuclease-sensitive regions of human spermatozoal chromatin are highly enriched in promoter and CTCF binding sequences

(2009) A. Arpanahi et al.   GENOME RESEARCH

Correlation of expression and methylation of imprinted genes with pluripotency of parthenogenetic embryonic stem cells

(2009) Chao Li et al.   HUMAN MOLECULAR GENETICS

The XPA-binding domain of ERCC1 Is Required for Nucleotide Excision Repair but Not Other DNA Repair Pathways

(2009) Barbara Orelli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The regulated retrotransposon transcriptome of mammalian cells

(2009) Geoffrey J Faulkner et al.   NATURE GENETICS

Short-Term Calorie Restriction in Male Mice Feminizes Gene Expression and Alters Key Regulators of Conserved Aging Regulatory Pathways

(2009) Preston Wayne Estep et al.   PLoS One

The Culture of Zygotes to the Blastocyst Stage Changes the Postnatal Expression of an Epigentically Labile Allele, Agouti Viable Yellow, in Mice1

(2008) Hugh D. Morgan et al.   BIOLOGY OF REPRODUCTION

Long-Term Effects of Mouse Intracytoplasmic Sperm Injection with DNA-Fragmented Sperm on Health and Behavior of Adult Offspring1

(2008) Raúl Fernández-Gonzalez et al.   BIOLOGY OF REPRODUCTION

Intergenerational Transmission of Glucose Intolerance and Obesity by In Utero Undernutrition in Mice

(2008) J. C. Jimenez-Chillaron et al.   DIABETES

Paternal effect on embryo quality in diabetic mice is related to poor sperm quality and associated with decreased glucose transporter expression

(2008) Sung Tae Kim et al.   REPRODUCTION

Analysis of gene transcription alterations at the blastocyst stage related to the long-term consequences of in vitro culture in mice

(2008) Raúl Fernández-González et al.   REPRODUCTION

A genome-wide screen for modifiers of transgene variegation identifies genes with critical roles in development

(2008) Alyson Ashe et al.   GENOME BIOLOGY