Article
Oncology
Natalie L. Wu, Kevin R. Krull, Kara L. Cushing-Haugen, Nicole J. Ullrich, Nina S. Kadan-Lottick, Stephanie J. Lee, Eric J. Chow
Summary: Although long-term survivors of pediatric HCT reported higher rates of impairment in specific neurocognitive domains, cognitive quality of life was perceived as similar to the general population. Subsets of survivors with certain co-morbidities had substantially worse neurocognitive outcomes.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Article
Multidisciplinary Sciences
Jiaoyang Cai, Yin Ting Cheung, Phillip Lung Wai Au-Doung, Wenting Hu, Yijin Gao, Hua Zhang, Mingjing Ji, Shuhong Shen, Jing Chen, Jingyan Tang
Summary: This study aimed to evaluate psychosocial outcomes in Chinese pediatric survivors of cancer or conditions requiring hematopoietic stem cell transplantation (HSCT), and to identify clinical and behavioral factors associated with adverse psychosocial outcomes. The study found that survivors with multiple health problems, higher pain interference, more sleep problems, and longer screen time had worse emotional, social, attention, and behavior functioning. It suggests that survivors diagnosed at a younger age or with unaddressed/untreated health problems may require additional psychological evaluation, and psychosocial assessments during routine long-term follow-up care can help identify high-risk patients during the early phase of survivorship. Rehabilitation interventions should also address modifiable behavioral factors such as sleep habits, screen time, and chronic pain.
Article
Oncology
Yeji Lee, Inho Kim, Youngil Koh, Dongyeop Shin, Junshik Hong, Chang Won Lee, Kwan Sik Seo
Summary: This study investigated the impact of hematopoietic stem cell transplantation (HSCT) on physical function. Results showed that one-third of the patients experienced physical impairment during the acute transplant period, and patients with low physical function were more likely to suffer from depression and have lower quality of life.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Oncology
Sina A. Beer, Stefan Wirths, Wichard Vogel, Ghazaleh Tabatabai, Ulrike Ernemann, David A. Merle, Wolfgang Bethge, Robert Moehle, Claudia Lengerke
Summary: Elderly patients show better quality of life after high-dose chemotherapy and autologous stem cell transplantation, challenging the assumption of insufficient recovery in the elderly. HDC/ASCT is an effective therapy with respect to disease control, overall health status, and quality of life, irrespective of patient age.
Article
Oncology
Jianfei Xie, Ziyu Wan, Yinglong Duan, Miao Wang, Yating Luo, Panpan Xiao, Yue Kang, Yi Zhou, Xiaofei Luo, Qian Sun, Andy S. K. Cheng
Summary: In AYA patients undergoing HSCT, LM therapy significantly alleviated depression and salivary cortisol levels, as well as improved quality of life.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Transplantation
Aaltje L. Ziengs, Anne M. Buunk, Lisanne van Sonderen, Michele F. Eisenga, Antonio W. Gomes Neto, Coby Annema, Thialda Vlagsma, Gerjan J. Navis, Stefan P. Berger, Stephan J. L. Bakker, Jacoba M. Spikman
Summary: This study reveals long-term cognitive impairments in kidney transplant recipients that are not related to disease-related variables. Poorer cognitive functioning is significantly associated with lower levels of societal participation and quality of life.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2023)
Article
Oncology
Giana Berleze Penna, Tassiana Costa da Silva, Alessandra Aparecida Paz, Bruna Ziegler
Summary: Hematopoietic stem cell transplantation (HSCT) is utilized in treating various diseases. This study found that HSCT survivors experience long-term changes in functional capacity, pulmonary function, and quality of life, with more active individuals showing better outcomes in pulmonary function and functional capacity.
SUPPORTIVE CARE IN CANCER
(2021)
Article
Oncology
Kristin Pulewka, Bernhard Strauss, Andreas Hochhaus, Inken Hilgendorf
Summary: The study found that there are differences in medical, psychological, and social needs between adolescents and young adults as well as older patients after HSCT, indicating the importance of age-appropriate informational materials to meet these diverse needs.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
(2021)
Article
Oncology
Kader Caliskan, Gulbeyaz Can
Summary: This descriptive study aimed to determine the symptoms experienced by patients who received hematopoietic stem cell transplantation (HSCT) at home in the early period, identify coping behaviors used by the patients, and assess their quality of life. The study included 200 patients who had received HSCT and been discharged. The results showed that pain, weakness, and loss of appetite were the most frequently experienced symptoms. Most patients complied with coping behaviors, but these behaviors were only partially effective. Clinical diagnosis, transplant type, re-hospitalization status, and number of problems experienced significantly affected symptoms and quality of life.
SUPPORTIVE CARE IN CANCER
(2022)
Article
Rheumatology
Leonardo Pippa Gadioli, Karla Costa-Pereira, Juliana B. E. Dias, Daniela A. Moraes, Julio C. Crescencio, Pedro Schwartzmann, Lourenco Gallo, Andre Schmidt, Maria Carolina Oliveira
Summary: This study aimed to assess the cardiopulmonary function outcomes of SSc patients after Autologous Hematopoietic Stem Cell Transplantation (AHSCT). The results showed significant improvements in peak VO2, percentage of predicted peak VO2, and 6-minute walk test distance after AHSCT. The improvements in peak VO2 were positively correlated with improvements in 6-minute walk test distance and negatively correlated with resting heart rate decrease. All patients showed improved VO2 values after AHSCT, regardless of baseline diffusing capacity for carbon monoxide (DLCO) levels. The increase in VO2 levels after AHSCT was positively correlated with increases in the physical component scores of the Short Form-36 quality of life questionnaire.
Letter
Clinical Neurology
Robert A. Gross, Yan Yuan, Chris Keran, Janis M. Miyasaki
Summary: The study shows that aHSCT can prevent disability worsening in the majority of multiple sclerosis (MS) patients and induce durable improvement in disability, especially in patients with relapsing-remitting MS. The use of the BEAM + ATG conditioning protocol is associated with a more pronounced suppression of clinical relapses and MRI inflammatory activity.
Article
Psychiatry
Michaela Doring, Anna Karina Dette, Dustin Werle, Ricarda Jendritza, Carmen Malaval, Stefanie Thiel, Sebastian Michaelis, Manuel Schlosser, Peter Lang, Rupert Handgretinger, Jennifer Svaldi, Karin Melanie Cabanillas Stanchi
Summary: This study investigated the psychological and somatic distress of pediatric and young adult patients during hematopoietic stem cell transplantation (HSCT). The results showed that both autologous and allogeneic HSCT were associated with reduced quality of life and increased distress. The allogeneic group experienced higher levels of psychological distress compared to the autologous group.
JOURNAL OF PSYCHOSOMATIC RESEARCH
(2023)
Article
Sport Sciences
Melanie Potiaumpai, Stacy Cutrono, Tamia Medina, Maximillian Koeppel, Denise L. Pereira, William F. Pirl, Kevin A. Jacobs, Moataz Eltoukhy, Joseph F. Signorile
Summary: A multidirectional walking program during the transplant period can significantly improve aerobic capacity and quality of life for patients, showing a positive impact on physical function and QOL.
MEDICINE & SCIENCE IN SPORTS & EXERCISE
(2021)
Article
Oncology
Lathika Mohanraj, Lana Sargent, R. K. Elswick, Amir Toor, Theresa Swift-Scanlan
Summary: This study found that frailty and cognitive impairment in autologous HSCT recipients were associated with increased fatigue and decreased quality of life. These findings are important for nurses to understand and mitigate the effects of HSCT.
Review
Hematology
Steffen T. Simon, Anne Pralong, Michael Hallek, Christoph Scheid, Udo Holtick, Marco Herling
Summary: Patients undergoing allogeneic stem cell transplantation (allo-SCT) require supportive and palliative care, with common issues being fatigue and psychological distress, while chronic GvHD significantly impacts quality of life. There is a lack of research on further issues related to allo-SCT.
ANNALS OF HEMATOLOGY
(2021)
