Review
Physiology
Bokai Zhu
Summary: The mammalian liver deals with various metabolic and physiological changes that occur daily. This article presents evidence of temporal compartmentalization of hepatic metabolic processes and discusses the role of circadian and ultradian clocks in regulating these processes in mouse liver.
Article
Biochemistry & Molecular Biology
Andreas Psomas, Namrata R. Chowdhury, Benita Middleton, Raphaelle Winsky-Sommerer, Debra J. Skene, Menno P. Gerkema, Daan R. van Der Veen
Summary: This study investigated the metabolic rhythms in the plasma metabolome of voles and found that there were both 24-hour circadian rhythms and faster 2-4 hour ultradian rhythms. These ultradian rhythms were synchronized with the circadian rhythms and were not aligned with meal timing, indicating their importance in metabolic regulation.
Article
Biochemistry & Molecular Biology
Himanshu K. Mishra, Noelle M. Ying, Angelica Luis, Heather Wei, Metta Nguyen, Timothy Nakhla, Sara Vandenburgh, Martin Alda, Wade H. Berrettini, Kristen J. Brennand, Joseph R. Calabrese, William H. Coryell, Mark A. Frye, Fred H. Gage, Elliot S. Gershon, Melvin G. McInnis, Caroline M. Nievergelt, John I. Nurnberger, Paul D. Shilling, Ketil J. Oedegaard, Peter P. Zandi, R. Kelsoe John, David K. Welsh, Michael J. McCarthy
Summary: Neuronal circadian rhythm abnormalities are present in patients with bipolar disorder, with the most pronounced deficits observed in individuals who do not respond to lithium treatment. Stimulation of entrainment pathways may partly reverse these rhythm deficits.
MOLECULAR PSYCHIATRY
(2021)
Article
Clinical Neurology
Bruno Etain, Manon Meyrel, Vincent Hennion, Frank Bellivier, Jan Scott
Summary: The study found that actigraphy parameters were associated with response to lithium treatment and could correctly classify BD cases. The model was robust in BD-I patients but not in BD-II patients. Despite limitations, the findings support the use of actigraphy for real-time monitoring of lithium response.
JOURNAL OF AFFECTIVE DISORDERS
(2021)
Article
Biochemical Research Methods
Capucine Martin, Jonathan D. Johnston, Erin A. Henslee, Daan R. van der Veen, Fatima H. Labeed
Summary: Research reveals that the electrical properties in adipocytes play a crucial role in peripheral clock regulation, independent of transcription-translation feedback loops. Using dielectrophoresis, significant electrophysiological rhythms were observed in pre-adipocytes, with circadian (around 24 hours) cycles in membrane capacitance and radius properties, and ultradian (around 14 hours) rhythms in membrane conductance.
Article
Endocrinology & Metabolism
Katherine A. English, Viral Chikani, Christina Jang, Goce Dimeski, Sarah Olson, Warrick J. Inder
Summary: The study found that post-operative ACTH levels lower than 14.3 pmol/L predicted the need for glucocorticoid replacement therapy, while patients with ACTH levels greater than or equal to 14.3 pmol/L did not require this treatment at 6 months. There was a significant circadian variation in ACTH and cortisol levels between 0700-0900 on the first day post-op.
CLINICAL ENDOCRINOLOGY
(2021)
Article
Physiology
Isaiah J. Ting, Andreas Psomas, Debra J. Skene, Daan R. van der Veen
Summary: Ultradian rhythms in various physiological processes are co-expressed with circadian rhythms, and have a close link to metabolic homeostasis. Low energy availability enhances ultradian rhythmicity at the cellular level.
FRONTIERS IN PHYSIOLOGY
(2023)
Review
Behavioral Sciences
Yifan Yao, Rae Silver
Summary: This article explores the relationship between the circadian timing system (CTS) and circulating steroids, focusing on the brain clock located in the suprachiasmatic nucleus (SCN), the daily fluctuations in plasma steroids, the mechanisms producing these fluctuations, and the actions of steroids on their receptors within the SCN. The findings suggest that there is a mutual shaping of responses between the brain clock and fluctuating plasma steroid levels.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE
(2022)
Article
Multidisciplinary Sciences
Frank A. J. L. Scheer, Michael F. Hilton, Heather L. Evoniuk, Sally A. Shiels, Atul Malhotra, Rena Sugarbaker, R. Timothy Ayers, Elliot Israel, Anthony F. Massaro, Steven A. Shea
Summary: The study found that asthma patients experience worsened lung function and exacerbation of symptoms at night, often masked by sleep. Asthma patients exhibit significant circadian rhythms throughout the day and are more likely to use bronchodilators during the night.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Review
Biochemistry & Molecular Biology
Abdurrahman Coskun, Atefeh Zarepour, Ali Zarrabi
Summary: The concentration of biomolecules in living systems exhibits systematic and random variations. Systematic variations can be classified into ultradian, circadian, and infradian rhythms based on their frequency, while random biological variations include variations between individuals and within individuals. Physiological rhythms and random biological variations are important for predictive, preventive, and personalized laboratory medicine.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Review
Biochemistry & Molecular Biology
Heather Ballance, Bokai Zhu
Summary: Biological oscillations often cycle at different harmonics of the 24-hour circadian rhythms, but the 12-hour oscillation is also evolutionarily conserved and gaining attention. The 12-hour rhythms are mainly regulated by XBP1s, generating cycles of gene expression.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2021)
Article
Multidisciplinary Sciences
Arlex Marin-Garcia, Ruben Fossion, Markus F. Mueller, Wady Rios-Herrera, Ana Leonor Rivera
Summary: Both parametric and non-parametric approaches to time-series analysis have advantages and disadvantages. Parametric methods can yield inconsistent results, while non-parametric methods are more widely applicable but sensitive to noise and low density data. Parametric methods are crucial in studying healthy and diseased populations when dealing with periodic phenomena.
ROYAL SOCIETY OPEN SCIENCE
(2022)
Article
Clinical Neurology
Monica Federoff, Michael J. McCarthy, Amit Anand, Wade H. Berrettini, Holli Bertram, Abesh Bhattacharjee, Cynthia Calkin, Carla Conroy, William H. Coryell, Nicole D'Arcangelo, Anna DeModena, Carrie Fisher, Scott Feeder, Nicole Frazier, Mark A. Frye, Keming Gao, Julie Garnham, Elliot S. Gershon, Ney Alliey-Rodriguez, Kara Glazer, Fernando Goes, Toyomi Karberg, Gloria Harrington, Petter Jakobsen, Masoud Kamali, Marisa Kelly, Susan G. Leckband, Falk Lohoff, Adam X. Maihofer, Melvin G. McInnis, Francis Mondimore, Gunnar Morken, John Nurnberger, Ketil J. Oedegaard, Megan Ritchey, Kelly Ryan, Martha Schinagle, Helle Schoeyen, Candice Schwebel, Martha Shaw, Paul D. Shilling, Claire Slaney, Andrea Stautland, Bruce Tarwater, Joseph R. Calabrese, Martin Alda, Caroline M. Nievergelt, Peter P. Zandi, John R. Kelsoe
Summary: Exposure to lithium is associated with reduced circadian disruption, and lithium response at 12 weeks was selectively associated with the reduction of circadian depressive symptoms.
Article
Chemistry, Medicinal
Jan Scott, Mohamed Lajnef, Romain Icick, Frank Bellivier, Cynthia Marie-Claire, Bruno Etain
Summary: This study compared different approaches to phenotyping the response to lithium in bipolar disorder patients, finding that machine learning methods were more effective in identifying potential signals of the lithium response compared to established approaches.
Review
Biochemistry & Molecular Biology
Johannes Burtscher, Erich Hohenauer, Martin Burtscher, Gregoire P. Miller, Margit Egg
Summary: Reduced oxygen availability can lead to cell and organ damage. Hypoxia inducible factors (HIFs) and mitochondria play a crucial role in the cellular response to hypoxia and help to counteract its detrimental consequences. Understanding the interaction between HIFs and mitochondria is essential for tackling hypoxia-related pathologies and harnessing the health benefits of controlled hypoxia exposures.
FREE RADICAL BIOLOGY AND MEDICINE
(2023)
Article
Psychology
Marco Bertamini, Rebecca Lawson, Luke Jones, Madeline Winters
ATTENTION PERCEPTION & PSYCHOPHYSICS
(2010)
Article
Behavioral Sciences
Jakub Spaeti, Mirjam Muench, Katharina Blatter, Vera Knoblauch, Luke A. Jones, Christian Cajochen
BEHAVIOURAL BRAIN RESEARCH
(2009)
Article
Psychology
Ruth S. Ogden, J. H. Wearden, Luke A. Jones
JOURNAL OF EXPERIMENTAL PSYCHOLOGY-HUMAN PERCEPTION AND PERFORMANCE
(2008)
Article
Psychology, Biological
Luke A. Jones, Ellen Poliakoff, Jill Wells
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2009)
Article
Psychology, Biological
Ruth S. Ogden, Luke A. Jones
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2009)
Article
Psychology, Biological
Ruth S. Ogden, John H. Wearden, Luke A. Jones
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2010)
Article
Psychology, Biological
Luke A. Jones, Clare S. Allely, John H. Wearden
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2011)
Article
Psychology, Biological
Ruth S. Ogden, Luke A. Jones
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2011)
Article
Psychology, Biological
John H. Wearden, Luke A. Jones
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2013)
Meeting Abstract
Ophthalmology
Elizabeth Lewis, Ellen Poliakoff, Luke Jones, Emma Gowen
Proceedings Paper
Psychology, Multidisciplinary
Luke A. Jones
INTERNATIONAL CONFERENCE ON TIMING AND TIME PERCEPTION
(2014)
Article
Psychology, Experimental
Alexis D. J. Makin, Ellen Poliakoff, Joe Dillon, Aimee Perrin, Thomas Mullet, Luke A. Jones
Article
Psychology, Experimental
R. S. Ogden, E. Salominaite, L. A. Jones, J. E. Fisk, C. Montgomery
Article
Psychology, Biological
J. H. Wearden, Luke A. Jones
QUARTERLY JOURNAL OF EXPERIMENTAL PSYCHOLOGY
(2007)