Article
Chemistry, Analytical
Wang Ren, Ying Zhang, Wen Yong Liang, Xiu Pei Yang, Wei Dong Jiang, Xiao Hong Liu, Wei Zhang
Summary: The study developed a ratiometric fluorescence sensor for trace resorcinol using a specific coupling reaction between RS and dopamine, achieving rapid and sensitive visual discrimination. The sensor successfully detected RS in real water samples, demonstrating its convenience for routine analysis and field monitoring of trace RS.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Applied
Yongqiang Shi, Wenting Li, Xuping Feng, Lei Lin, Pengcheng Nie, Jiyong Shi, Xiaobo Zou, Yong He
Summary: A novel aptamer-modified Copper @ Gold nanoclusters based ratiometric fluorescent probe was developed for mercury ions determination in Porphyra, with a detection limit of 4.92 nM. Additionally, a homemade device for colorimetric determination of Hg2+ was designed, showing good portability and usefulness. The study suggests the considerable potential of these methods for evaluating Hg2+ levels in aquatic products.
Article
Chemistry, Analytical
Cheng Li, Qian-Qi Yang, Tian-Jiao Zhang, Zhao-Zi Lv, Yong Wang, Yu Chen
Summary: The study introduces a hybrid ratiometric fluorescence sensor for efficient and accurate detection of dissolved CO2, which was proven effective for determining the CO2 concentration in real samples. This is the first report of a water-soluble, quantitatively CO2-responsive, ratiometric fluorescence sensor synergizing TPE and Au NCs in the amino-rich hyperbranched skeleton without the participation of any free organic compounds.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Nanoscience & Nanotechnology
Hui Xiang, Shiyu He, Gan Zhao, Mengting Zhang, Jian Lin, Lina Yang, Honglin Liu
Summary: Investigations have shown that hydrogen sulfide (H2S) can finely regulate the surface structure of gold nanoclusters (AuNCs) and further quench their fluorescence. A novel ratiometric fluorescence probe (RBDA) was developed, which exhibited a rapid and intuitive fluorescence response to H2S with high sensitivity and selectivity. The probe demonstrated high biostability, low cytotoxicity, and good biocompatibility.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Analytical
Qiang Li, Xiaomeng Zhou, Li-Li Tan, Li Shang
Summary: Ultrasmall gold nanoclusters (AuNCs) with distinct photoluminescence properties were effectively modulated by encapsulating them into zeolite imidazolate frameworks-8 (ZIF-8), resulting in enhanced near-infrared (NIR) fluorescence intensity. The AuNCs@ZIF-8 composites exhibited an emission maximum at 830 nm, longer than AuNCs without ZIF-8 encapsulation. This strategy was utilized for the detection of acetylcholinesterase (AChE) using a ratiometric fluorescent sensing platform, showing high sensitivity and good specificity in biological samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Shiyu He, Hui Xiang, Gan Zhao, Mengting Zhang, Jian Lin, Lina Yang, Honglin Liu
Summary: Developing reliable probes for accurate monitoring peroxynitrite (ONOO-) in living systems is crucial for understanding its functions in diseases and improving therapies. In this study, a novel nano-assembly structure (D-AuGP) was developed using gold nanoclusters (Au NCs) and induced fluorescence resonance energy transfer (FRET). The probe showed a quantitative ratiometric fluorescence response toward ONOO- with good stability and biocompatibility. It was successfully used for biological imaging and monitoring ONOO- levels in living cells and zebrafish.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Hong-Xin Ren, Zhi-Juan Qian, Min Li, Chi-Fang Peng, Zhou-Ping Wang, Xin-Lin Wei, Jian-Guo Xu
Summary: By preparing a core-shell QDs@mSiO(2)@y-AuNCs nanoprobe, a new ratiometric fluorescent sensor for thiram detection was successfully developed. The mechanism of thiram sensing was attributed to the formation of Au-S bonds between thiram and Au atoms on y-AuNCs surface, leading to the dissociation of 11-MUA ligand from the y-AuNCs surface and the charge transfer between thiram and y-AuNCs. The ratiometric fluorescence detection of thiram based on QDs@mSiO(2)@y-AuNCs showed a 3-fold enhanced sensitivity compared to fluorescence detection based on y-AuNCs, with a linear range of 0.5-60 ng/mL and a LOD of 0.19 ng/mL.
Article
Chemistry, Analytical
Mengke Wang, Junyang Chen, Shan Jiang, Yixin Nie, Xingguang Su
Summary: A novel fluorescent method for polynucleotide kinase (PNK) activity analysis was developed using gold nanoclusters and dsDNA-intercalating dye, presenting a sensitive and simple ratio fluorescent strategy for PNK determination.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Multidisciplinary
Xiaomeng Zhou, Xinjie Wang, Li Shang
Summary: A novel dual-emissive fluorescence nanoplatform was designed for ATP sensing based on red emissive europium metal-organic framework (Eu-MOF) and blue emissive gold nanoclusters (AuNCs). The presence of ATP caused the decomposition of Eu-MOF, resulting in a decrease in red emission while the blue emission of AuNCs remained unchanged. This emission intensity change enabled the establishment of a ratiometric fluorescent and visual sensor of ATP. A fluorescent paper-based sensor was also fabricated for easy-to-use and visual detection of ATP in serum samples using a smartphone.
CHINESE CHEMICAL LETTERS
(2023)
Article
Chemistry, Analytical
Yuchi Cheng, Huangmei Zhou, Jinming Xu, Yu Zhao, Xihang Chen, Rodolphe Antoine, Meng Ding, Kun Zhang, Sanjun Zhang
Summary: A two-photon excited ratiometric fluorescent pH sensor was developed by combining L-cysteine-protected AuNCs (Cys@AuNCs) with fluorescein isothiocyanate (FITC). The sensor showed a large dynamic range for pH measurement and had potential for sensitive quantitation of pH in living cells under two-photon excitation. In addition, the synthesized Cys@AuNCs exhibited excellent photoactivated peroxidase-like activity, promising for rapid colorimetric biosensing and control of catalytic reactions by photostimulation.
Article
Chemistry, Analytical
Xuanxuan An, Qin Tan, Shuang Pan, Shujun Zhen, Yongmei Hu, Xiaoli Hu
Summary: A dual-emission ratiometric fluorescent sensing system based on boron-doped carbon quantum dots and gold nanoclusters has been developed for the determination of xanthine. By utilizing the inner filter effect and the catalytic properties, the concentration of xanthine can be detected, showing good applicability in human urine samples.
Article
Chemistry, Physical
Jun Zhang, Ruchun Chen, Qizhen Chen, Yongmei Hu, Shuang Pan, Xiaoli Hu
Summary: This work presents an ascorbic acid sensing platform using MnO2 nanosheets and gold nanocluster as a ratiometric fluorescent probe, achieving a sensitive method for AA detection with a low limit of detection.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Analytical
Mengting Guan, Haibo He, Ruxing Li, Xiaojing Si, Xitian Peng, Xiaoxia Yan, Zhaosheng Yang, Enhsuan Nien, Yunyi Lei, Liqiang Luo
Summary: In this work, a La3+ assisted GSH-Au NCs/CDs nanoplatform was fabricated for sensitive detection of FEN. The fluorescence response of GSH-Au NCs was significantly enhanced by La3+ and further enhanced by the coordination between La3+ and FEN. The ratiometric fluorescence of GSH-Au NCs and CDs showed a good linear relationship with FEN concentration and exhibited good sensitivity at a low detection limit. The nanoplatform demonstrated desirable selectivity and applicability for monitoring trace level of FEN in fruit and vegetable samples. The non-enzymatic strategy using AIEE of GSH-Au NCs has a great potential for facile screening of organophosphate pesticides in agro-products.
ANALYTICA CHIMICA ACTA
(2022)
Article
Chemistry, Multidisciplinary
Lingyuan Liu, Shuyun Zhu, Jing Sun, Meng Xia, Xian'en Zhao, Guobao Xu
Summary: A ratiometric fluorescent sensing platform for bleomycin (BLM) has been designed using DNA-templated silver nanoclusters (DNA-AgNCs) probe, with a highly-sensitive detection limit of 30 pmol/L. The label-free fluorescence probe offers the advantages of convenient synthetic process and low cost, and has been successfully applied to the detection of BLM in human serum samples, showing potential for cancer therapy analysis.
CHINESE CHEMICAL LETTERS
(2021)
Article
Chemistry, Multidisciplinary
Jing Zhang, Ying Liu, Yang Liu, Wencai Liu, Fengniu Lu, Zhiqin Yuan, Chao Lu
Summary: This study explores the use of gold nanocluster-encapsulated hyperbranched polyethyleneimine as a specific and ratiometric dopamine nanoprobe. The nanoprobe shows rapid and sensitive dopamine detection due to the enhanced dopamine self-polymerization. It has favorable selectivity and stability for dopamine analysis in urine samples.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Analytical
A. Santhana Krishna Kumar, Wei-Bin Tseng, Man-Jyun Wu, Yzu-Yun Huang, Wei-Lung Tseng
ANALYTICA CHIMICA ACTA
(2020)
Article
Environmental Sciences
Shi-Wei Zhan, Wei-Bin Tseng, Wei-Lung Tseng
ENVIRONMENTAL RESEARCH
(2020)
Article
Chemistry, Physical
Jyun-Guo You, Dun-Yuan Jin, Wei-Bin Tseng, Wei-Lung Tseng, Po-Chiao Lin
Article
Chemistry, Analytical
Yi-Shan Li, Wei-Lung Tseng, Chi-Yu Lu
Article
Chemistry, Multidisciplinary
A. Santhana Krishna Kumar, Chi-Yu Lu, Wei-Lung Tseng
Summary: The study demonstrated the successful development of a nanosensor using FL-MnO2 NSs for sensitive detection of TNT, with a detection limit of 20 pM, and visualization of 10 nM TNT in drinking water and 10 μM TNT on a postal envelope by depositing PEI-FL-MnO2 NSs on filter paper under a UV lamp.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2021)
Article
Chemistry, Multidisciplinary
Emmanuvel Arputharaj, A. Santhana Krishna Kumar, Wei-Lung Tseng, Shiuh-Jen Jiang, Yeou-Lih Huang, Hans-Uwe Dahms
Summary: In this study, a nano-composite material, PEI-g-C3N4 NSs@LFs, was successfully used for the efficient capture of Cr(VI) from aqueous solutions. The material showed high adsorption efficiency and the ability to reduce Cr(VI) to Cr(III) under visible light. Additionally, it demonstrated excellent adsorption performance at various pH levels.
Article
Biochemical Research Methods
Yi-Shan Li, Jau-Ling Suen, Wei-Lung Tseng, Chi-Yu Lu
Summary: The study developed a peptide probe for the detection of acrylamide by MALDI-TOF MS, which allows for detection in small sample volumes with a limit of detection as low as 0.05 ng/mu L without the need for organic solvents. The developed method showed a relative standard deviation and relative error of < 6.7% for intra- and inter-day assays.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY
(2021)
Article
Biophysics
Wei-Bin Tseng, Yi-Shiuan Chou, Cheng-Zong Lu, Manivannan Madhu, Chi-Yu Lu, Wei-Lung Tseng
Summary: A dual-mode platform for sensing plasma heparin and imaging heparan sulfate proteoglycan-expressed cancer cells was developed by stabilizing the intramolecular charge transfer state. The platform exhibited excellent selectivity towards heparin and heparan sulfate, with two linear calibration curves for quantification. This platform was practically applied for the determination of plasma heparin and selective imaging of heparan sulfate proteoglycan-expressed cells.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Chemistry, Multidisciplinary
Cheng-Huan Chuang, Wan-Yi Chen, Wei-Bin Tseng, Aiyu Lin, Chi-Yu Lu, Wei-Lung Tseng
Summary: This study presents a rapid microwave synthetic approach for developing protein-stabilized gold nanoclusters (AuNCs) with near-infrared emission peaks. The incorporation of Ag(I) into these nanoclusters further enhances their luminescence properties. The synthesized nanoclusters can be used for colorimetric sensing and imaging, demonstrating excellent performance.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Environmental Sciences
Wei-Bin Tseng, Jui-Yeh Rau, Hung-Chi Chiou, Wei-Lung Tseng
Summary: This study developed a straightforward strategy to prepare lysozyme nanoparticle-encapsulated gold nanoclusters (LysNP-AuNCs) as a dual-emission probe for the ratiometric sensing of cyanide through fluorescence resonance energy transfer (FRET) without the conjugation of additional fluorophores. The LysNP-AuNC probe showed high selectivity for cyanide and was able to detect cyanide in tap water, soils, and cyanogenic glycoside-containing foods.
ENVIRONMENTAL RESEARCH
(2022)
Article
Chemistry, Analytical
Mohamed Gamal Mohamed, Huan-Yu Hu, Manivannan Madhu, Mohsin Ejaz, Santosh U. Sharma, Wei-Lung Tseng, Maha Mohamed Samy, Cheng-Wei Huang, Jyh-Tsung Lee, Shiao-Wei Kuo
Summary: In this study, novel 2D conjugated microporous polymers (Th-F-CMP) containing thiophene and fluorene moieties were successfully prepared using the one-pot polycondensation method. The Th-F-CMP exhibited excellent thermal properties and pore structure. Furthermore, Th-F-CMP showed promising potential as a fluorescence probe for selective detection of Fe3+ ions and as an energy storage electrode with outstanding electrochemical performance and cycle stability.
Article
Chemistry, Analytical
Manivannan Madhu, A. Santhana Krishna Kumar, Chi -Yu Lu, Wei -Lung Tseng
Summary: This study fabricated yellow-emitting CDs and applied them as a fluorescence turn-on platform for the sensitive and selective detection of lipopolysaccharide (LPS). By designing a peptide that triggers the aggregation of CDs, the fluorescence of CDs can be turned on. This peptide specifically interacts with LPS at neutral pH. The study demonstrated that this method has a fast response time, a wide linear range, a low detection limit, and excellent selectivity for detecting LPS.
Article
Chemistry, Multidisciplinary
Manivannan Madhu, Chi-Yu Lu, Wei-Lung Tseng
Summary: Few-layer molybdenum disulfide quantum dots embedded in poly(vinyl alcohol) matrices exhibit enhanced phosphorescence with a long lasting time, making them suitable for temperature detection and anti-counterfeiting ink. The bright phosphorescence is attributed to the formation of hydrogen bonding networks between FL-MoS2 QDs and PVA molecules, providing a new direction for potential applications in sensors and security inks.
NANOSCALE ADVANCES
(2021)
Review
Food Science & Technology
Wei-Bin Tseng, Ming-Mu Hsieh, Che-Hsie Chen, Tai-Chia Chiu, Wei-Lung Tseng
JOURNAL OF FOOD AND DRUG ANALYSIS
(2020)
Review
Chemistry, Analytical
A. Santhana Krishna Kumar, Wei-Lung Tseng
ANALYTICAL METHODS
(2020)