Squalene monooxygenase – a target for hypercholesterolemic therapy

Cholesterol-Dependent Degradation of Squalene Monooxygenase, a Control Point in Cholesterol Synthesis beyond HMG-CoA Reductase

(2011) Saloni Gill et al.   Cell Metabolism

Regulation of microsomal triglyceride transfer protein

(2011) M Mahmood Hussain et al.   Clinical Lipidology

The Incremental Value of Lipids and Inflammatory Biomarkers in Determining Residual Cardiovascular Risk

(2011) Sandeep S. Mangalmurti et al.   Current Atherosclerosis Reports

Progress in HDL-Based Therapies for Atherosclerosis

(2011) Kuang-Yuh Chyu et al.   Current Atherosclerosis Reports

Lipid transport by mammalian ABC proteins

(2011) Faraz Quazi et al.   Essays in Biochemistry

Detailed Mechanism of Squalene Epoxidase Inhibition by Terbinafine

(2011) Marcin Nowosielski et al.   Journal of Chemical Information and Modeling

A High-Content RNAi-Screening Assay to Identify Modulators of Cholesterol Accumulation in Niemann–Pick Type C Cells

(2010) Shilpi Arora et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Mipomersen as a potential adjunctive therapy for hypercholesterolemia

(2010) Neeraj Patel et al.   EXPERT OPINION ON PHARMACOTHERAPY

Advancing therapy for hypercholesterolemia

(2010) Konstantinos Toutouzas et al.   EXPERT OPINION ON PHARMACOTHERAPY

Good news for 'good' cholesterol

(2010) Alla Katsnelson   NATURE

microRNAs and cholesterol metabolism

(2010) Kathryn J. Moore et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Basic Science Review Section: Statin Therapy—Part II: Clinical Considerations for Cardiovascular Disease

(2010) Benjamin Sadowitz et al.   Vascular and Endovascular Surgery

Apolipoprotein B and Cardiovascular Disease Risk: Position Statement from the AACC Lipoproteins and Vascular Diseases Division Working Group on Best Practices

(2009) J. H. Contois et al.   CLINICAL CHEMISTRY

Garlic: Nature's Protection Against Physiological Threats

(2009) Masood Sadiq Butt et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Vaccination, squalene and anti-squalene antibodies: Facts or fiction?

(2009) Giuseppe Lippi et al.   European Journal of Internal Medicine

Statins, fibrates, nicotinic acid, cholesterol absorption inhibitors, anion-exchange resins, omega-3 fatty acids: which drugs for which patients?

(2009) Heinz Drexel   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Stereoselective epoxidation of the last double bond of polyunsaturated fatty acids by human cytochromes P450

(2009) Danièle Lucas et al.   JOURNAL OF LIPID RESEARCH

Beyond blood lipids: phytosterols, statins and omega-3 polyunsaturated fatty acid therapy for hyperlipidemia

(2009) Michelle A. Micallef et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Squalene Emulsions for Parenteral Vaccine and Drug Delivery

(2009) Christopher Fox   MOLECULES

Getting a handle on Huntington's disease: the case for cholesterol

(2009) Masahisa Katsuno et al.   NATURE MEDICINE

Regulation of ginsenoside and phytosterol biosynthesis by RNA interferences of squalene epoxidase gene in Panax ginseng

(2009) Jung-Yeon Han et al.   PHYTOCHEMISTRY

Structure-Function Correlations of Two Highly Conserved Motifs in Saccharomyces cerevisiae Squalene Epoxidase

(2008) C. Ruckenstuhl et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

PCSK9 binds to multiple receptors and can be functionally inhibited by an EGF-A peptide

(2008) LiXin Shan et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Novel nonstatin strategies to lower low-density lipoprotein cholesterol

(2008) Michael H. Davidson   Current Atherosclerosis Reports

Simvastatin with or without Ezetimibe in Familial Hypercholesterolemia

(2008) John J.P. Kastelein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: A randomized, double blind placebo controlled trial

(2008) Rafe Bundy et al.   PHYTOMEDICINE

Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates

(2008) M. Frank-Kamenetsky et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety of MF59™ adjuvant

(2008) Viola Schultze et al.   VACCINE