4.7 Article

xQTL workbench: a scalable web environment for multi-level QTL analysis

Journal

BIOINFORMATICS
Volume 28, Issue 7, Pages 1042-1044

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/bts049

Keywords

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Funding

  1. National Institutes of Health [GM074244]
  2. Netherlands Organisation for Scientific Research (NWO)/TTI Green Genetics [1CC029RP]
  3. NWO [825.09.008]
  4. Centre for BioSystems Genomics (CBSG)
  5. Netherlands Consortium of Systems Biology (NCSB)
  6. Netherlands Bioinformatics Center (NBIC)
  7. Netherlands Genomics Initiative/NWO
  8. European Regional Development Fund
  9. EU [222936, 241504]

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xQTL workbench is a scalable web platform for the mapping of quantitative trait loci (QTLs) at multiple levels: for example gene expression (eQTL), protein abundance (pQTL), metabolite abundance (mQTL) and phenotype (phQTL) data. Popular QTL mapping methods for model organism and human populations are accessible via the web user interface. Large calculations scale easily on to multi-core computers, clusters and Cloud. All data involved can be uploaded and queried online: markers, genotypes, microarrays, NGS, LC-MS, GC-MS, NMR, etc. When new data types come available, xQTL workbench is quickly customized using the Molgenis software generator.

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