Uniformly curated signaling pathways reveal tissue-specific cross-talks and support drug target discovery

NetPath: a public resource of curated signal transduction pathways

(2010) Kumaran Kandasamy et al.   GENOME BIOLOGY

Network analyses in systems pharmacology

(2009) S. I. Berger et al.   BIOINFORMATICS

Orphan receptor tyrosine kinase ROR2 as a potential therapeutic target for osteosarcoma

(2009) Kazuhito Morioka et al.   CANCER SCIENCE

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

(2009) Nikolay Borisov et al.   Molecular Systems Biology

PI3K-dependent cross-talk interactions converge with Ras as quantifiable inputs integrated by Erk

(2009) Chun-Chao Wang et al.   Molecular Systems Biology

Pathway databases and tools for their exploitation: benefits, current limitations and challenges

(2009) Anna Bauer-Mehren et al.   Molecular Systems Biology

Synthetic Gene Networks That Count

(2009) A. E. Friedland et al.   SCIENCE

PDTD: a web-accessible protein database for drug target identification

(2008) Zhenting Gao et al.   BMC BIOINFORMATICS

PRINCESS, a Protein Interaction Confidence Evaluation System with Multiple Data Sources

(2008) Dong Li et al.   MOLECULAR & CELLULAR PROTEOMICS

Network pharmacology: the next paradigm in drug discovery

(2008) Andrew L Hopkins   Nature Chemical Biology

Literature-curated protein interaction datasets

(2008) Michael E Cusick et al.   NATURE METHODS

McKusick's Online Mendelian Inheritance in Man (OMIM(R))

(2008) J. Amberger et al.   NUCLEIC ACIDS RESEARCH

InterPro: the integrative protein signature database

(2008) S. Hunter et al.   NUCLEIC ACIDS RESEARCH