Journal
BIOINFORMATICS
Volume 26, Issue 16, Pages 2060-2061Publisher
OXFORD UNIV PRESS
DOI: 10.1093/bioinformatics/btq328
Keywords
-
Categories
Funding
- Ministerio de Ciencia e Innovacion [FIS2009-10352]
- University of California, Davis
Ask authors/readers for more resources
Macromolecular assembly coordinates essential cellular processes, such as gene regulation and signal transduction. A major challenge for conventional computational methods to study these processes is tackling the exponential increase of the number of configurational states with the number of components. CplexA is a Mathematica package that uses functional programming to efficiently compute probabilities and average properties over such exponentially large number of states from the energetics of the interactions. The package is particularly suited to study gene expression at complex promoters controlled by multiple, local and distal, DNA binding sites for transcription factors.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available