Loss of caspase-2 accelerates age-dependent alterations in mitochondrial production of reactive oxygen species

Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice

(2012) S Shalini et al.   CELL DEATH AND DIFFERENTIATION

Methyl methanesulfonate induces apoptosis in p53-deficient H1299 and Hep3B cells through a caspase 2- and mitochondria-associated pathway

(2012) Ying Jiang et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-2: the orphan caspase

(2011) L Bouchier-Hayes et al.   CELL DEATH AND DIFFERENTIATION

Loss of Caspase-2-dependent Apoptosis Induces Autophagy after Mitochondrial Oxidative Stress in Primary Cultures of Young Adult Cortical Neurons

(2011) Meenakshi Tiwari et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hormesis, cellular stress response and vitagenes as critical determinants in aging and longevity

(2011) Vittorio Calabrese et al.   MOLECULAR ASPECTS OF MEDICINE

Inhibitors of Succinate: Quinone Reductase/Complex II Regulate Production of Mitochondrial Reactive Oxygen Species and Protect Normal Cells from Ischemic Damage but Induce Specific Cancer Cell Death

(2011) Stephen J. Ralph et al.   PHARMACEUTICAL RESEARCH

Execution of Superoxide-Induced Cell Death by the Proapoptotic Bcl-2-Related Proteins Bid and Bak

(2009) M. Madesh et al.   MOLECULAR AND CELLULAR BIOLOGY

Mitochondrial function as a determinant of life span

(2009) Ian R. Lanza et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice

(2008) Melissa Braga et al.   APOPTOSIS

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

The enigma of caspase-2: the laymen's view

(2008) G Krumschnabel et al.   CELL DEATH AND DIFFERENTIATION