Hormesis: why it is important to biogerontologists

DNA damaging agents and p53 do not cause senescence in quiescent cells, while consecutive re-activation of mTOR is associated with conversion to senescence

(2016) Olga V. Leontieva et al.   Aging-US

The choice between p53-induced senescence and quiescence is determined in part by the mTOR pathway

(2016) Lioubov G. Korotchkina et al.   Aging-US

Hormesis does not make sense except in the light of TOR-driven aging

(2016) Mikhail V. Blagosklonny   Aging-US

Hormesis, cell death and aging

(2016) Isabelle Martins et al.   Aging-US

Longevity-relevant regulation of autophagy at the level of the acetylproteome

(2011) Guillermo Mariño et al.   Autophagy

Time- and Dose-Dependent Induction of HSP70 in Lemna minor Exposed to Different Environmental Stressors

(2011) Stefan Tukaj et al.   BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY

Calorie restriction: Decelerating mTOR-driven aging from cells to organisms (including humans)

(2011) Mikhail V Blagosklonny   CELL CYCLE

Toxicology rewrites its history and rethinks its future: Giving equal focus to both harmful and beneficial effects

(2011) Edward J. Calabrese   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome

(2011) Eugenia Morselli et al.   JOURNAL OF CELL BIOLOGY

Extension of Lifespan in C. elegans by Naphthoquinones That Act through Stress Hormesis Mechanisms

(2011) Piper R. Hunt et al.   PLoS One

The hormesis database: The occurrence of hormetic dose responses in the toxicological literature

(2011) Edward J. Calabrese et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

Hormesis provides a generalized quantitative estimate of biological plasticity

(2011) Edward J. Calabrese et al.   Journal of Cell Communication and Signaling

Rapamycin Extends Maximal Lifespan in Cancer-Prone Mice

(2010) Vladimir N. Anisimov et al.   AMERICAN JOURNAL OF PATHOLOGY

Caloric restriction delays cardiac ageing in rats: role of mitochondria

(2010) Bernd Niemann et al.   CARDIOVASCULAR RESEARCH

Weak p53 permits senescence during cell cycle arrest

(2010) Olga V. Leontieva et al.   CELL CYCLE

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Biphasic effects of chronic ethanol exposure on insulin-stimulated glucose uptake in primary cultured rat skeletal muscle cells: role of the Akt pathway and GLUT4

(2010) Wei Qu et al.   DIABETES-METABOLISM RESEARCH AND REVIEWS

Mimetics of Hormetic Agents: Stress-Resistance Triggers

(2010) Joan Smith Sonneborn   Dose-Response

Lead-contaminated soil induced oxidative stress, defense response and its indicative biomarkers in roots of Vicia faba seedlings

(2010) Chengrun Wang et al.   ECOTOXICOLOGY

Parthenin hormesis in plants depends on growth conditions

(2010) Regina G. Belz et al.   ENVIRONMENTAL AND EXPERIMENTAL BOTANY

Homeopathy: Clarifying its relationship to hormesis

(2010) Edward J Calabrese et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Evaluating homeopathic drugs within a biomedical framework

(2010) Edward J Calabrese et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Resveratrol commonly displays hormesis: Occurrence and biomedical significance

(2010) Edward J Calabrese et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Can autophagy promote longevity?

(2010) Frank Madeo et al.   NATURE CELL BIOLOGY

Paradoxical suppression of cellular senescence by p53

(2010) Z. N. Demidenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of mTOR coincides with autophagy during ligation-induced atrophy in the rat submandibular gland

(2010) N Silver et al.   Cell Death & Disease

Caloric restriction and resveratrol promote longevity through the Sirtuin-1-dependent induction of autophagy

(2010) E Morselli et al.   Cell Death & Disease

Anti- and pro-tumor functions of autophagy

(2009) Eugenia Morselli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Loss of cardioprotection with ageing

(2009) K. Boengler et al.   CARDIOVASCULAR RESEARCH

Alcohol Consumption and Risk of Cardiovascular Disease and Death in Women

(2009) Luc Djoussé et al.   CIRCULATION

Alcohol as a Risk Factor for Type 2 Diabetes: A systematic review and meta-analysis

(2009) D. O. Baliunas et al.   DIABETES CARE

Clinical Application of Ischemic Preconditioning in the Elderly

(2009) Pasquale Abete et al.   Dose-Response

The Hormetic Morphogen Theory of Curvature and the Morphogenesis and Pathology of Tubular and other Curved Structures

(2009) Egil Fosslien   Dose-Response

Stress to the Rescue: Is Hormesis a ‘Cure’ for Aging?

(2009) Arnold Kahn et al.   Dose-Response

A Perspective on the Scientific, Philosophical, and Policy Dimensions of Hormesis

(2009) George R. Hoffmann   Dose-Response

The IKK complex contributes to the induction of autophagy

(2009) Alfredo Criollo et al.   EMBO JOURNAL

Amyloid β serves as an NGF-like neurotrophic factor or acts as a NGF antagonist depending on its concentration

(2009) Maria-Ángeles Arevalo et al.   JOURNAL OF NEUROCHEMISTRY

Induction of autophagy by spermidine promotes longevity

(2009) Tobias Eisenberg et al.   NATURE CELL BIOLOGY

Dose-Response Features of Neuroprotective Agents: An Integrative Summary

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Neuroscience and Hormesis: Overview and General Findings

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Stress Biology and Hormesis: The Yerkes–Dodson Law in Psychology—A Special Case of the Hormesis Dose Response

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

An Assessment of Anxiolytic Drug Screening Tests: Hormetic Dose Responses Predominate

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Alzheimer's Disease Drugs: An Application of the Hormetic Dose-Response Model

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Modulation of the Epileptic Seizure Threshold: Implications of Biphasic Dose Responses

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Pharmacological Enhancement of Neuronal Survival

(2008) Edward J. Calabrese   CRITICAL REVIEWS IN TOXICOLOGY

Hormesis and plant biology

(2008) Edward J. Calabrese et al.   ENVIRONMENTAL POLLUTION

HORMESIS: WHY IT IS IMPORTANT TO TOXICOLOGY AND TOXICOLOGISTS

(2008) Edward J. Calabrese   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Hormesis Predicts Low-Dose Responses Better Than Threshold Models

(2008) Edward J. Calabrese et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Best in small doses

(2008) Mark Mattson et al.   NEW SCIENTIST

Converging concepts: Adaptive response, preconditioning, and the Yerkes–Dodson Law are manifestations of hormesis

(2007) Edward J. Calabrese   AGEING RESEARCH REVIEWS

Cardioprotection by Ischemic Postconditioning Is Lost in Aged and STAT3-Deficient Mice

(2007) Kerstin Boengler et al.   CIRCULATION RESEARCH