Design and construction of small perturbation mutagenesis libraries for antibody affinity maturation using massive microchip-synthesized oligonucleotides

Title
Design and construction of small perturbation mutagenesis libraries for antibody affinity maturation using massive microchip-synthesized oligonucleotides
Authors
Keywords
Antibody affinity maturation, Small perturbation mutagenesis, Microchip oligonucleotide synthesis, Next-generation sequencing, Phage display
Journal
JOURNAL OF BIOTECHNOLOGY
Volume 194, Issue -, Pages 27-36
Publisher
Elsevier BV
Online
2014-11-17
DOI
10.1016/j.jbiotec.2014.11.007

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