Sphingosine-1-phosphate signaling in physiology and diseases

Engagement of S1P1-degradative mechanisms leads to vascular leak in mice

(2011) Myat Lin Oo et al.   JOURNAL OF CLINICAL INVESTIGATION

Lipid phosphate phosphatase 3 enables efficient thymic egress

(2011) Béatrice Bréart et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The sphingosine 1-phosphate receptor S1P2 maintains the homeostasis of germinal center B cells and promotes niche confinement

(2011) Jesse A Green et al.   NATURE IMMUNOLOGY

S1P2, the G Protein-Coupled Receptor for Sphingosine-1-Phosphate, Negatively Regulates Tumor Angiogenesis and Tumor Growth In vivo in Mice

(2010) W. Du et al.   CANCER RESEARCH

Sphingosine-1-phosphate produced by sphingosine kinase 2 in mitochondria interacts with prohibitin 2 to regulate complex IV assembly and respiration

(2010) Graham M. Strub et al.   FASEB JOURNAL

Sphingosine 1-Phosphate Lyase Deficiency Disrupts Lipid Homeostasis in Liver

(2010) Meryem Bektas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sphingosine kinase 1 and sphingosine-1-phosphate receptor 2 are vital to recovery from anaphylactic shock in mice

(2010) Ana Olivera et al.   JOURNAL OF CLINICAL INVESTIGATION

Sphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2

(2010) Sergio E. Alvarez et al.   NATURE

International Union of Basic and Clinical Pharmacology. LXXVIII. Lysophospholipid Receptor Nomenclature

(2010) J. Chun et al.   PHARMACOLOGICAL REVIEWS

Differential regulation of sphingosine kinases 1 and 2 in lung injury

(2009) Raj Wadgaonkar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Export and functions of sphingosine-1-phosphate

(2009) Roger H. Kim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Targeted Disruption of the S1P2 Sphingosine 1-Phosphate Receptor Gene Leads to Diffuse Large B-Cell Lymphoma Formation

(2009) G. Cattoretti et al.   CANCER RESEARCH

Sphingosine-1-phosphate receptor signalling in the heart

(2009) C. K. Means et al.   CARDIOVASCULAR RESEARCH

Sphingosine-1-phosphate and modulation of vascular tone

(2009) Junsuke Igarashi et al.   CARDIOVASCULAR RESEARCH

Incomplete Inhibition of Sphingosine 1-Phosphate Lyase Modulates Immune System Function yet Prevents Early Lethality and Non-Lymphoid Lesions

(2009) Peter Vogel et al.   PLoS One

Regulation of Histone Acetylation in the Nucleus by Sphingosine-1-Phosphate

(2009) N. C. Hait et al.   SCIENCE

Sphingosine-1-phosphate lyase in development and disease: Sphingolipid metabolism takes flight

(2008) H FYRST   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system

(2008) Y TAKUWA   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Vascular Endothelium As a Contributor of Plasma Sphingosine 1-Phosphate

(2008) Krishnan Venkataraman et al.   CIRCULATION RESEARCH

Bioactive sphingolipids: metabolism and function

(2008) Nana Bartke et al.   JOURNAL OF LIPID RESEARCH

Dendritic cell PAR1–S1P3 signalling couples coagulation and inflammation

(2008) Frank Niessen et al.   NATURE

The Sphingolipid Transporter Spns2 Functions in Migration of Zebrafish Myocardial Precursors

(2008) A. Kawahara et al.   SCIENCE