Article
Transplantation
George H. B. Greenhall, Matthew Robb, Rachel J. Johnson, Maria Ibrahim, Rachel Hilton, Laurie A. Tomlinson, Chris J. Callaghan, Christopher J. E. Watson
Summary: This study examined the relationship between deceased donor albuminuria and kidney utilization, survival, and function. The findings suggest that kidneys from donors with albuminuria are less likely to be accepted for transplantation, but there is no evidence of an association between albuminuria and graft survival or function.
NEPHROLOGY DIALYSIS TRANSPLANTATION
(2022)
Article
Public, Environmental & Occupational Health
Francesca Leonardis, Lara Gitto, Evaldo Favi, Angelo Oliva, Roberta Angelico, Annapaola Mitterhofer, Irene Cacciola, Domenico Santoro, Tommaso Maria Manzia, Giuseppe Tisone, Roberto Cacciola
Summary: This study applies the Keynesian principle to Kidney Transplantation (KT) and explores the financial resources that can be obtained from the activity. The results show that the savings generated from KT exceed the costs of Organ Donation (OD) and have the potential for growth. These savings can contribute to the financial self-sufficiency of the Organ Donation and Transplantation (ODT) service.
FRONTIERS IN PUBLIC HEALTH
(2023)
Article
Urology & Nephrology
Yingxin Lin, Armando Teixeira-Pinto, Jonathan C. Craig, Helen Opdam, Jeremy C. Chapman, Henry Pleass, Angus Carter, Natasha M. Rogers, Christopher E. Davies, Stephen McDonald, Jean Yang, Wai H. Lim, Germaine Wong
Summary: The trajectory of blood pressure decline in kidneys donated after circulatory death can predict the risk of delayed graft function. The assessment of haemodynamic changes in donors during the agonal phase may be useful for determining donor suitability and post-transplant outcomes.
CLINICAL KIDNEY JOURNAL
(2023)
Article
Urology & Nephrology
Paulina Kurleto, Lucyna Tomaszek, Irena Milaniak, Katrina A. Bramstedt
Summary: A study in Poland examined public opinion on living kidney donation, finding strong support for legalization of unspecified living kidney donation. However, some respondents expressed concerns about the risk of organ trafficking.
Article
Psychology, Clinical
Mira Zuchowski, Nizam Mamode, Heather Draper, Peter Gogalniceanu, Sam Norton, Joseph Chilcot, Alexis Clarke, Lynsey Williams, Timothy Auburn, Hannah Maple
Summary: This study aimed to investigate the experiences of individuals involved in the UK UKD scheme, including those who completed the donation, were eventually medically withdrawn, or self-withdrew. The study found that individuals who did not proceed to donation expressed dissatisfaction and lingering emotional consequences linked to lack of follow-up from transplant teams.
BRITISH JOURNAL OF HEALTH PSYCHOLOGY
(2021)
Review
Medicine, General & Internal
Nora M. M. Laskowski, Gerrit Brandt, Katharina Tigges-Limmer, Georg Halbeisen, Georgios Paslakis
Summary: Organ transplantation is a physically and psychologically burdensome experience for recipients, leading to the development of donor and donation images (DDI). This scoping review aimed to present the current state of knowledge on DDI among transplant recipients. Twenty-one studies on heart, lung, or kidney transplant recipients were included, showing a prevalence of DDI ranging from 6% to 52.3%. DDI occurs both before and after transplantation and can influence the recipient's personality and well-being.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Immunology
Leyla R. Herbst, Kayleigh Herrick-Reynolds, Laura Bowles Zeiser, Julia Lopez, Amber Kernodle, Awura Asamoah-Mensah, Tanjala Purnell, Dorry L. Segev, Allan B. Massie, Elizabeth King, Jacqueline Garonzik-Wang, Andrew M. Cameron
Summary: This study found that the number of living donor liver transplants, including those from NDDs, has been increasing over the past decade but remains concentrated at few centers. Adult and pediatric recipients of NDD liver transplants were more frequently female and diagnosed with biliary atresia. There were no observed racial inequities in the distribution of NDD grafts at different centers for adult or pediatric patients.
Review
Ethics
Daniel Rodger, Bonnie Venter
Summary: Every year in England, many patients die while waiting for a kidney transplant, indicating that the current altruistic-based donation system is insufficient to address the kidney shortage. To tackle this problem, we propose a monopsony system where kidney donors can choose to receive financial compensation. By doing so, numerous lives could be saved, waiting times for transplants could be reduced, and the burden on dialysis services could be lessened. Additionally, compensation would help overcome disincentives to donation and increase awareness of living kidney donation, while also resulting in cost savings for healthcare.
MEDICINE HEALTH CARE AND PHILOSOPHY
(2023)
Article
Urology & Nephrology
Dylan Isaacson, Jesse D. Schold, Michael W. Gmeiner, Hannah C. Copley, Vasilis Kosmoliaptsis, Anat R. Tambur
Summary: This study found that HLA-DQ mismatches had the strongest association with donor-specific antibodies, particularly in African American and Hispanic recipients. The effect of HLA-DQ on calculated panel reactive antibody (cPRA) increase was equivalent or larger than any other HLA locus. Therefore, the effects of HLA-DQ should be considered in kidney allocation.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Surgery
Dwight D. Harris, Aaron Fleishman, Martha Pavlakis, Martin R. Pollak, Prabhakar K. Baliga, Vinayak Rohan, Liise K. Kayler, James R. Rodrigue
Summary: This study investigated the attitudes of African Americans towards ApoL1 testing. The results showed that most participants believed transplant programs should offer ApoL1 testing and supported potential kidney donors having the autonomy to make donation decisions or participate in shared decision-making. Furthermore, the majority of transplant candidates expressed reluctance to accept kidneys from individuals with the high-risk genotype.
JOURNAL OF SURGICAL RESEARCH
(2022)
Article
Urology & Nephrology
Masoud Barah, Vikram Kilambi, John J. Friedewald, Sanjay Mehrotra
Summary: Reducing discard is crucial for the US transplantation system, and shorter cold ischemia time and closer proximity to the donor increase the acceptability of marginal organs.
CLINICAL JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
(2022)
Article
Multidisciplinary Sciences
Eunjeong Kang, Jangwook Lee, Sehoon Park, Yaerim Kim, Hyo Jeong Kim, Yong Chul Kim, Dong Ki Kim, Kwon Wook Joo, Yon Su Kim, Insun Choi, Hajeong Lee
Summary: This study aimed to investigate the recognition of live kidney donation among the general population in Korea. The results showed that although the majority of participants understood and were knowledgeable about living donor kidney transplantation, only half of them were willing to donate due to concerns about possible complications. The study also found that most participants agreed on the need for social and economic support for living kidney donors, particularly in terms of surgery-related costs.
Article
Medicine, General & Internal
Saaliha Vali, Benjamin P. Jones, Sairah Sheikh, Srdjan Saso, Isabel Quiroga, J. Richard Smith
Summary: The study found that the general public in the United Kingdom holds a favorable view towards uterus transplantation (UTx) and is willing to donate their uterus after death. However, there is a lack of awareness about UTx among the population, highlighting the need for education.
FRONTIERS IN MEDICINE
(2023)
Article
Computer Science, Information Systems
Diana Hawashin, Raja Jayaraman, Khaled Salah, Ibrar Yaqoob, Mecit Can Emre Simsekler, Samer Ellahham
Summary: This paper proposes a blockchain-based solution for organ donation and transplantation management that is secure, traceable, and trustworthy. The solution utilizes smart contracts and algorithms to ensure a fair and efficient process.
Article
Urology & Nephrology
Guillermo Garcia-Garcia, Marcello Tonelli, Margarita Ibarra-Hernandez, Jonathan S. Chavez-Iniguez, Ma. Concepcion Oseguera-Vizcaino
Summary: Access to kidney transplantation in Mexico is limited to more than half of the population, primarily due to factors such as fragmented health system, gender disparities, and sociocultural issues. Efforts to increase deceased-organ donation rates and implement comprehensive kidney care programs could help address these inequalities in access to kidney transplantation.