Mild cold-stress depresses immune responses: Implications for cancer models involving laboratory mice

Fit-for purpose use of mouse models to improve predictivity of cancer therapeutics evaluation

(2014) K. Wartha et al.   PHARMACOLOGY & THERAPEUTICS

Stressful Presentations: Mild Cold Stress in Laboratory Mice Influences Phenotype of Dendritic Cells in Naïve and Tumor-Bearing Mice

(2014) Kathleen M. Kokolus et al.   Frontiers in Immunology

Beta2-adrenergic receptor signaling in CD4+Foxp3+regulatory T cells enhances their suppressive function in a PKA-dependent manner

(2013) Marcia G. Guereschi et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Elevated norepinephrine may be an etiological factor in a wide range of diseases: Age-related macular degeneration, systemic lupus erythematosus, atrial fibrillation, metabolic syndrome

(2013) Paul J. Fitzgerald   MEDICAL HYPOTHESES

Age and duration of inflammatory environment differentially affect the neuroimmune response and catecholaminergic neurons in the midbrain and brainstem

(2013) Isabelle Bardou et al.   NEUROBIOLOGY OF AGING

Impact of nesting material on mouse body temperature and physiology

(2013) Brianna N. Gaskill et al.   PHYSIOLOGY & BEHAVIOR

BMP7 Activates Brown Adipose Tissue and Reduces Diet-Induced Obesity Only at Subthermoneutrality

(2013) Mariëtte R. Boon et al.   PLoS One

Chronic Psychological Stress Induces the Accumulation of Myeloid-Derived Suppressor Cells in Mice

(2013) Jianfeng Jin et al.   PLoS One

Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via  -adrenergic induction of myelopoiesis

(2013) N. D. Powell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Baseline tumor growth and immune control in laboratory mice are significantly influenced by subthermoneutral housing temperature

(2013) K. M. Kokolus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selection for increased mass-independent maximal metabolic rate suppresses innate but not adaptive immune function

(2013) C. J. Downs et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Autonomic Nerve Development Contributes to Prostate Cancer Progression

(2013) C. Magnon et al.   SCIENCE

Cancer Immunotherapy

(2013) J. Couzin-Frankel   SCIENCE

Effects of ambient temperature on adaptive thermogenesis during maintenance of reduced body weight in mice

(2012) Yann Ravussin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Sympathetic Nervous System Regulates Bone Marrow–Derived Cell Egress Through Endothelial Nitric Oxide Synthase Activation

(2012) Alice Récalde et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Norepinephrine reuptake inhibition promotes mobilization in mice: potential impact to rescue low stem cell yields

(2012) D. Lucas et al.   BLOOD

Early impact of social isolation and breast tumor progression in mice

(2012) Kelley S. Madden et al.   BRAIN BEHAVIOR AND IMMUNITY

Below Thermoneutrality, Changes in Activity Do Not Drive Changes in Total Daily Energy Expenditure between Groups of Mice

(2012) Sam Virtue et al.   Cell Metabolism

Norepinephrine differentially modulates the innate inflammatory response provoked by amyloid-β peptide via action at β-adrenoceptors and activation of cAMP/PKA pathway in human THP-1 macrophages

(2012) Ji Hye Yang et al.   EXPERIMENTAL NEUROLOGY

Endothelial Cells Are Able to Synthesize and Release Catecholamines Both In Vitro and In Vivo

(2012) Daniela Sorriento et al.   HYPERTENSION

Unstressing intemperate models: how cold stress undermines mouse modeling

(2012) Christopher L. Karp   JOURNAL OF EXPERIMENTAL MEDICINE

Norepinephrine suppresses IFN-γ and TNF-α production by murine intestinal intraepithelial lymphocytes via the β1 adrenoceptor

(2012) Yasuhiro Takayanagi et al.   JOURNAL OF NEUROIMMUNOLOGY

Thermal physiology of laboratory mice: Defining thermoneutrality

(2012) C.J. Gordon   JOURNAL OF THERMAL BIOLOGY

Interleukin-1 beta simultaneously affects the stress and reproductive axes by modulating norepinephrine levels in different brain areas

(2012) Madhu P. Sirivelu et al.   LIFE SCIENCES

Heat or Insulation: Behavioral Titration of Mouse Preference for Warmth or Access to a Nest

(2012) Brianna N. Gaskill et al.   PLoS One

Immune Sculpting of Norepinephrine on MHC-I, B7-1, IDO and B7-H1 Expression and Regulation of Proliferation and Invasion in Pancreatic Carcinoma Cells

(2012) Liancai Wang et al.   PLoS One

Effects of Ambient Temperature on Sleep and Cardiovascular Regulation in Mice: The Role of Hypocretin/Orexin Neurons

(2012) Viviana Lo Martire et al.   PLoS One

Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression

(2012) Suzanne Ostrand-Rosenberg et al.   SEMINARS IN CANCER BIOLOGY

Nerve-cancer interactions in the stromal biology of pancreatic cancer

(2012) Ihsan Ekin Demir   Frontiers in Physiology

Basal Forebrain Thermoregulatory Mechanism Modulates Auto-Regulated Sleep

(2012) Hruda Nanda Mallick et al.   Frontiers in Neurology

Not so hot: Optimal housing temperatures for mice to mimic the thermal environment of humans

(2012) John R. Speakman et al.   Molecular Metabolism

Beta blockers, norepinephrine, and cancer: an epidemiological viewpoint

(2012) P J Fitzgerald   Clinical Epidemiology

Metabolic characteristics of long-lived mice

(2012) Andrzej Bartke et al.   Frontiers in Genetics

Regulation of pancreatic cancer by neuropsychological stress responses: a novel target for intervention

(2011) H. M. Schuller et al.   CARCINOGENESIS

Molecular Pathways: Beta-Adrenergic Signaling in Cancer: Figure 1.

(2011) Steven W. Cole et al.   CLINICAL CANCER RESEARCH

β2-Adrenoreceptors of regulatory lymphocytes are essential for vagal neuromodulation of the innate immune system

(2011) Gergely Vida et al.   FASEB JOURNAL

Thermoregulatory Phenotype of the Trpv1 Knockout Mouse: Thermoeffector Dysbalance with Hyperkinesis

(2011) A. Garami et al.   JOURNAL OF NEUROSCIENCE

Working with what you’ve got: Changes in thermal preference and behavior in mice with or without nesting material

(2011) Brianna N. Gaskill et al.   JOURNAL OF THERMAL BIOLOGY

Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

(2011) Khoa D. Nguyen et al.   NATURE

Metabolic Changes in Skin Caused by Scd1 Deficiency: A Focus on Retinol Metabolism

(2011) Matthew T. Flowers et al.   PLoS One

Impaired ventilatory and thermoregulatory responses to hypoxic stress in newborn Phox2b heterozygous knock-out mice

(2011) Nelina Ramanantsoa   Frontiers in Physiology

Social isolation is associated with elevated tumor norepinephrine in ovarian carcinoma patients

(2010) Susan K. Lutgendorf et al.   BRAIN BEHAVIOR AND IMMUNITY

Stimulation of β2-adrenergic receptors inhibits calcineurin activity in CD4+ T cells via PKA–AKAP interaction

(2010) Carsten Riether et al.   BRAIN BEHAVIOR AND IMMUNITY

Effects of Estradiol on the Thermoneutral Zone and Core Temperature in Ovariectomized Rats

(2010) Penny A. Dacks et al.   ENDOCRINOLOGY

The pain, depression, and fatigue symptom cluster in advanced breast cancer: Covariation with the hypothalamic–pituitary–adrenal axis and the sympathetic nervous system.

(2010) Lisa M. Thornton et al.   HEALTH PSYCHOLOGY

Brain Perivascular Macrophages and the Sympathetic Response to Inflammation in Rats After Myocardial Infarction

(2010) Yang Yu et al.   HYPERTENSION

Feeling too hot or cold after breast cancer: Is it just a nuisance or a potentially important prognostic factor?

(2010) Kathleen M. Kokolus et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

Nonshivering thermogenesis and its adequate measurement in metabolic studies

(2010) B. Cannon et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Chronic Individual Housing-Induced Stress Decreased Expression of Catecholamine Biosynthetic Enzyme Genes and Proteins in Spleen of Adult Rats

(2010) Ljubica Gavrilovic et al.   NEUROIMMUNOMODULATION

Metabolic adaptation of mice in a cool environment

(2010) Kunitoshi Uchida et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

"Control" laboratory rodents are metabolically morbid: Why it matters

(2010) B. Martin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

EXTENT AND MAGNITUDE OF CATECHOLAMINE SURGE IN PEDIATRIC BURNED PATIENTS

(2010) Gabriela A. Kulp et al.   SHOCK

Breath-to-breath hypercapnic response in neonatal rats: temperature dependency of the chemoreflexes and potential implications for breathing stability

(2009) Kevin J. Cummings et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

UCP1 Ablation Induces Obesity and Abolishes Diet-Induced Thermogenesis in Mice Exempt from Thermal Stress by Living at Thermoneutrality

(2009) Helena M. Feldmann et al.   Cell Metabolism

Upregulation of Phagocyte-Derived Catecholamines Augments the Acute Inflammatory Response

(2009) Michael A. Flierl et al.   PLoS One

Thermogenesis challenges the adipostat hypothesis for body-weight control

(2009) Barbara Cannon et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

Vagal tone dominates autonomic control of mouse heart rate at thermoneutrality

(2008) S. J. Swoap et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Some like it hot: Mouse temperature preferences in laboratory housing

(2008) Brianna N. Gaskill et al.   APPLIED ANIMAL BEHAVIOUR SCIENCE

Synergistic and additive actions of a psychosocial stressor and endotoxin challenge: Circulating and brain cytokines, plasma corticosterone and behavioral changes in mice

(2008) Julie Gibb et al.   BRAIN BEHAVIOR AND IMMUNITY

The anticancer immune response: indispensable for therapeutic success?

(2008) Laurence Zitvogel et al.   JOURNAL OF CLINICAL INVESTIGATION

Renal contribution to thermolability in rats: role of renal nerves

(2008) N. A. Lutaif et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Temperature regulates limb length in homeotherms by directly modulating cartilage growth

(2008) M. A. Serrat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA