DNA replication timing: Coordinating genome stability with genome regulation on the X chromosome and beyond

A new light on DNA replication from the inactive X chromosome

(2014) Mirit I. Aladjem et al.   BIOESSAYS

Every Cell Is Special: Genome-wide Studies Add a New Dimension to Single-Cell Biology

(2014) Jan Philipp Junker et al.   CELL

Single Cell Genomics: Advances and Future Perspectives

(2014) Iain C. Macaulay et al.   PLoS Genetics

Hypermutation of the Inactive X Chromosome Is a Frequent Event in Cancer

(2013) Natalie Jäger et al.   CELL

Chromatin dynamics at the replication fork: there's more to life than histones

(2013) Iestyn Whitehouse et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Random replication of the inactive X chromosome

(2013) A. Koren et al.   GENOME RESEARCH

Mutational heterogeneity in cancer and the search for new cancer-associated genes

(2013) Michael S. Lawrence et al.   NATURE

Genome-wide copy number profiling of single cells in S-phase reveals DNA-replication domains

(2013) Niels Van der Aa et al.   NUCLEIC ACIDS RESEARCH

Titration of Four Replication Factors Is Essential for the Xenopus laevis Midblastula Transition

(2013) C. Collart et al.   SCIENCE

High-Resolution Replication Profiles Define the Stochastic Nature of Genome Replication Initiation and Termination

(2013) Michelle Hawkins et al.   Cell Reports

Asynchronous Replication, Mono-Allelic Expression, and Long Range Cis-Effects of ASAR6

(2013) Nathan Donley et al.   PLoS Genetics

Differential Relationship of DNA Replication Timing to Different Forms of Human Mutation and Variation

(2012) Amnon Koren et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype

(2012) Marta B Davidson et al.   EMBO JOURNAL

Conservation of replication timing reveals global and local regulation of replication origin activity

(2012) C. A. Muller et al.   GENOME RESEARCH

Replication timing and its emergence from stochastic processes

(2012) John Bechhoefer et al.   TRENDS IN GENETICS

Origin Association of Sld3, Sld7, and Cdc45 Proteins Is a Key Step for Determination of Origin-Firing Timing

(2011) Seiji Tanaka et al.   CURRENT BIOLOGY

Limiting replication initiation factors execute the temporal programme of origin firing in budding yeast

(2011) Davide Mantiero et al.   EMBO JOURNAL

GENETIC VARIATION AND DNA REPLICATION TIMING, OR WHY IS THERE LATE REPLICATING DNA?

(2011) John Herrick   EVOLUTION

An autosomal locus that controls chromosome-wide replication timing and mono-allelic expression

(2011) Eric P. Stoffregen et al.   HUMAN MOLECULAR GENETICS

Analyses of X-linked and autosomal genetic variation in population-scale whole genome sequencing

(2011) Srikanth Gottipati et al.   NATURE GENETICS

Variation in genome-wide mutation rates within and between human families

(2011) Donald F Conrad et al.   NATURE GENETICS

Gracefully ageing at 50, X-chromosome inactivation becomes a paradigm for RNA and chromatin control

(2011) Jeannie T. Lee   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Evidence for Sequential and Increasing Activation of Replication Origins along Replication Timing Gradients in the Human Genome

(2011) Guillaume Guilbaud et al.   PLoS Computational Biology

Chromatin as a potential carrier of heritable information

(2010) Paul D Kaufman et al.   CURRENT OPINION IN CELL BIOLOGY

Replication timing as an epigenetic mark

(2010) Ichiro Hiratani et al.   Epigenetics

MRC1-dependent scaling of the budding yeast DNA replication timing program

(2010) A. Koren et al.   GENOME RESEARCH

Evolutionarily conserved replication timing profiles predict long-range chromatin interactions and distinguish closely related cell types

(2010) T. Ryba et al.   GENOME RESEARCH

Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing

(2010) Scott Cheng-Hsin Yang et al.   Molecular Systems Biology

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Comparative Analysis of DNA Replication Timing Reveals Conserved Large-Scale Chromosomal Architecture

(2010) Eitan Yaffe et al.   PLoS Genetics

Replication timing and transcriptional control: beyond cause and effect—part II

(2009) Ichiro Hiratani et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Chromatin state marks cell-type- and gender-specific replication of the Drosophila genome

(2009) M. Schwaiger et al.   GENES & DEVELOPMENT

Predictable dynamic program of timing of DNA replication in human cells

(2009) R. Desprat et al.   GENOME RESEARCH

Timing of Replication Is a Determinant of Neutral Substitution Rates but Does Not Explain Slow Y Chromosome Evolution in Rodents

(2009) C. J. Pink et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human mutation rate associated with DNA replication timing

(2009) John A Stamatoyannopoulos et al.   NATURE GENETICS

Replication timing and epigenetic reprogramming of gene expression: a two-way relationship?

(2009) Anita Göndör et al.   NATURE REVIEWS GENETICS

Control of DNA Replication by Anomalous Reaction-Diffusion Kinetics

(2009) Michel G. Gauthier et al.   PHYSICAL REVIEW LETTERS

Universal Temporal Profile of Replication Origin Activation in Eukaryotes

(2009) Arach Goldar et al.   PLoS One

Sequencing newly replicated DNA reveals widespread plasticity in human replication timing

(2009) R. S. Hansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Dynamic Stochastic Model for DNA Replication Initiation in Early Embryos

(2008) Arach Goldar et al.   PLoS One

Global Reorganization of Replication Domains During Embryonic Stem Cell Differentiation

(2008) Ichiro Hiratani et al.   PLOS BIOLOGY