Protein partners of KCTD proteins provide insights about their functional roles in cell differentiation and vertebrate development

Identification and Characterization of KCASH2 and KCASH3, 2 Novel Cullin3 Adaptors Suppressing Histone Deacetylase and Hedgehog Activity in Medulloblastoma

(2015) Enrico De Smaele et al.   NEOPLASIA

KCTD9 contributes to liver injury through NK cell activation during hepatitis B virus-induced acute-on-chronic liver failure

(2013) Tao Chen et al.   CLINICAL IMMUNOLOGY

Inhibition of neural crest formation by Kctd15 involves regulation of transcription factor AP-2

(2013) V. E. Zarelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The importance of being modified: PCNA modification and DNA damage response

(2012) Inbal gazy et al.   CELL CYCLE

Zebrafish enhancer trap line showing maternal and neural expression of kctd15a

(2012) Naouel Gharbi et al.   DEVELOPMENT GROWTH & DIFFERENTIATION

Identification and characterization of Xenopus kctd15, an ectodermal gene repressed by the FGF pathway

(2012) Chika Takahashi et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Opposite Effects of KCTD Subunit Domains on GABABReceptor-mediated Desensitization

(2012) Riad Seddik et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inactivation of MARK4, an AMP-activated Protein Kinase (AMPK)-related Kinase, Leads to Insulin Hypersensitivity and Resistance to Diet-induced Obesity

(2012) Chao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obscurin and KCTD6 regulate cullin-dependent small ankyrin-1 (sAnk1.5) protein turnover

(2012) Stephan Lange et al.   MOLECULAR BIOLOGY OF THE CELL

FGF10 and FGF21 as Regulators in Adipocyte Development and Metabolism

(2012) Hiroya Ohta et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

PrPC interacts with potassium channel tetramerization domain containing 1 (KCTD1) protein through the PrP51-136 region containing octapeptide repeats

(2011) Tao Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular organization of the cullin E3 ligase adaptor KCTD11

(2011) Stefania Correale et al.   BIOCHIMIE

SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex

(2011) Lifeng Feng et al.   CELL BIOCHEMISTRY AND FUNCTION

Cot/tpl2 activity is required for TLR-induced activation of the Akt p70 S6k pathway in macrophages: Implications for NO synthase 2 expression

(2011) Marta López-Peláez et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and lysosomal targeting of plasma membrane KCa3.1

(2011) Corina M. Balut et al.   FASEB JOURNAL

Pfetin as a Prognostic Biomarker for Gastrointestinal Stromal Tumor: Validation Study in Multiple Clinical Facilities

(2011) Daisuke Kubota et al.   JAPANESE JOURNAL OF CLINICAL ONCOLOGY

USP13 Enzyme Regulates Siah2 Ligase Stability and Activity via Noncatalytic Ubiquitin-binding Domains

(2011) Marzia Scortegagna et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

WIPI1 Coordinates Melanogenic Gene Transcription and Melanosome Formation via TORC1 Inhibition

(2011) Hsiang Ho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asymmetric Inhibition of Ulk2 Causes Left-Right Differences in Habenular Neuropil Formation

(2011) R. W. Taylor et al.   JOURNAL OF NEUROSCIENCE

Progressive Myoclonic Epilepsy-Associated Gene KCTD7 is a Regulator of Potassium Conductance in Neurons

(2011) Régis Azizieh et al.   MOLECULAR NEUROBIOLOGY

Toward an understanding of the protein interaction network of the human liver

(2011) J. Wang et al.   Molecular Systems Biology

Genome-Wide Population-Based Association Study of Extremely Overweight Young Adults – The GOYA Study

(2011) Lavinia Paternoster et al.   PLoS One

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

(2011) Jessica J. Howell et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Regulation of MITF stability by the USP13 deubiquitinase

(2011) Xiansi Zhao et al.   Nature Communications

PCNA Ubiquitination Is Important, But Not Essential for Translesion DNA Synthesis in Mammalian Cells

(2011) Ayal Hendel et al.   PLoS Genetics

Structural and Biochemical Analysis of the Pentapeptide Repeat ProteinEfsQnr, a Potent DNA Gyrase Inhibitor

(2010) Subray S. Hegde et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Protein phosphatase-1 regulates Akt1 signal transduction pathway to control gene expression, cell survival and differentiation

(2010) L Xiao et al.   CELL DEATH AND DIFFERENTIATION

Kctd15 inhibits neural crest formation by attenuating Wnt/ -catenin signaling output

(2010) S. Dutta et al.   DEVELOPMENT

Pharmacological modulation of voltage-gated potassium channels as a therapeutic strategy

(2010) Neil A Castle   EXPERT OPINION ON THERAPEUTIC PATENTS

The Role of Monoubiquitination in Endocytic Degradation of Human Ether-a-go-go-related Gene (hERG) Channels under Low K+Conditions

(2010) Tao Sun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Implication of Genetic Variants NearNEGR1,SEC16B,TMEM18,ETV5/DGKG,GNPDA2,LIN7C/BDNF,MTCH2,BCDIN3D/FAIM2,SH2B1,FTO,MC4R, andKCTD15with Obesity and Type 2 Diabetes in 7705 Chinese

(2010) Maggie C. Y. Ng et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Network organization of the human autophagy system

(2010) Christian Behrends et al.   NATURE

Native GABAB receptors are heteromultimers with a family of auxiliary subunits

(2010) Jochen Schwenk et al.   NATURE

Pro-apoptotic and antiproliferative activity of human KCNRG, a putative tumor suppressor in 13q14 region

(2010) Aybike Birerdinc et al.   TUMOR BIOLOGY

Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels

(2009) Hyder Usman et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

RhoB induces apoptosisviadirect interaction with TNFAIP1 in HeLa cells

(2009) Dong-Myung Kim et al.   INTERNATIONAL JOURNAL OF CANCER

The interaction of KCTD1 with transcription factor AP-2α inhibits its transactivation

(2009) Xiaofeng Ding et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Pentameric Assembly of Potassium Channel Tetramerization Domain-Containing Protein 5

(2009) Irina S. Dementieva et al.   JOURNAL OF MOLECULAR BIOLOGY

CK2 phosphorylates TNFAIP1 to affect its subcellular localization and interaction with PCNA

(2009) Liping Yang et al.   MOLECULAR BIOLOGY REPORTS

Cullin Mediates Degradation of RhoA through Evolutionarily Conserved BTB Adaptors to Control Actin Cytoskeleton Structure and Cell Movement

(2009) Yuezhou Chen et al.   MOLECULAR CELL

GABA’s Control of Stem and Cancer Cell Proliferation in Adult Neural and Peripheral Niches

(2009) Stephanie Z. Young et al.   PHYSIOLOGY

FRIGIDA Delays Flowering in Arabidopsis via a Cotranscriptional Mechanism Involving Direct Interaction with the Nuclear Cap-Binding Complex

(2009) N. Geraldo et al.   PLANT PHYSIOLOGY

Fibroblast growth factor receptor 1 is a key regulator of early adipogenic events in human preadipocytes

(2008) C. H. Widberg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Developmental origin of adipocytes: new insights into a pending question

(2008) Nathalie Billon et al.   BIOLOGY OF THE CELL

Characterization and Expression of a Human KCTD1 Gene Containing the BTB Domain, Which Mediates Transcriptional Repression and Homomeric Interactions

(2008) Xiao-Feng Ding et al.   DNA AND CELL BIOLOGY

KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases

(2008) Yolanda Bayón et al.   FEBS Journal

The Pentapeptide Repeat Proteins MfpAMt and QnrB4 Exhibit Opposite Effects on DNA Gyrase Catalytic Reactions and on the Ternary Gyrase-DNA-Quinolone Complex

(2008) A. Merens et al.   JOURNAL OF BACTERIOLOGY

Integrin-linked kinase localizes to the centrosome and regulates mitotic spindle organization

(2008) Andrew B. Fielding et al.   JOURNAL OF CELL BIOLOGY

A novel Akt/PKB-interacting protein promotes cell adhesion and inhibits familial amyotrophic lateral sclerosis-linked mutant SOD1-induced neuronal death via inhibition of PP2A-mediated dephosphorylation of Akt/PKB

(2007) Mikiro Nawa et al.   CELLULAR SIGNALLING