Interdependence of laforin and malin proteins for their stability and functions could underlie the molecular basis of locus heterogeneity in Lafora disease

Dysfunctions in endosomal–lysosomal and autophagy pathways underlie neuropathology in a mouse model for Lafora disease

(2011) Rajat Puri et al.   HUMAN MOLECULAR GENETICS

Lafora bodies and neurological defects in malin-deficient mice correlate with impaired autophagy

(2011) Olga Criado et al.   HUMAN MOLECULAR GENETICS

Malin and laforin are essential components of a protein complex that protects cells from thermal stress

(2011) S. Sengupta et al.   JOURNAL OF CELL SCIENCE

The Laforin-Malin Complex Negatively Regulates Glycogen Synthesis by Modulating Cellular Glucose Uptake via Glucose Transporters

(2011) P. K. Singh et al.   MOLECULAR AND CELLULAR BIOLOGY

Glycogen hyperphosphorylation underlies lafora body formation

(2010) Julie Turnbull et al.   ANNALS OF NEUROLOGY

Laforin, the most common protein mutated in Lafora disease, regulates autophagy

(2010) Carmen Aguado et al.   HUMAN MOLECULAR GENETICS

Lafora progressive myoclonus epilepsy: A meta-analysis of reported mutations in the first decade following the discovery of theEPM2AandNHLRC1genes

(2009) Shweta Singh et al.   HUMAN MUTATION

Increased Endoplasmic Reticulum Stress and Decreased Proteasomal Function in Lafora Disease Models Lacking the Phosphatase Laforin

(2009) Santiago Vernia et al.   PLoS One

Structure of the MDM2/MDMX RING domain heterodimer reveals dimerization is required for their ubiquitylation in trans

(2008) K Linke et al.   CELL DEATH AND DIFFERENTIATION

Regulation of apoptosis in Drosophila

(2008) H Steller   CELL DEATH AND DIFFERENTIATION

Modulation of functional properties of laforin phosphatase by alternative splicing reveals a novel mechanism for the EPM2A gene in Lafora progressive myoclonus epilepsy

(2008) D. Dubey et al.   HUMAN MOLECULAR GENETICS

The malin–laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin–proteasome system

(2008) Punitee Garyali et al.   HUMAN MOLECULAR GENETICS