Article
Chemistry, Analytical
Yalcin Altunkaynak, Omer Yavuz, Abdulkadir Levent
Summary: This work successfully determined vildagliptin at a pencil graphite electrode using cyclic voltammetry and square-wave voltammetry. A well-defined irreversible peak response was obtained, showing a good linear correlation between anodic current signal and concentration of vildagliptin. The developed voltammetric method was successfully applied for determination in pharmaceutical preparations and urine samples without the need for separation.
MICROCHEMICAL JOURNAL
(2021)
Article
Chemistry, Analytical
Michal Augustin, Rene Pfeifer, Jiroi Barek, Vlastimil Vyskocil
Summary: Electrochemical DNA biosensors have been widely used in various applications, and their application in monitoring DNA damage is particularly significant. A novel hybrid electrochemical DNA biosensor based on graphene was developed and optimized, and its performance in monitoring DNA damage was evaluated. The results showed that the biosensor has important advantages in monitoring DNA damage.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Natalia Festinger, Adrianna Lemiesz, Ewelina Skowron, Sylwia Smarzewska, Witold Ciesielski
Summary: A sensitive SWV method based on BPPGE and EPPGE was developed to determine the concentration of MAN in spiked samples, showing linear responses over specified concentration ranges. The method was successful in determining MAN with good recovery rates, and CV was used to understand the electrode process mechanism of MAN.
Article
Chemistry, Analytical
Ceren Yildiz, Dilek Eskikoy Bayraktepe, Zehra Yazan, Muserref Onal
Summary: This study presents a electrochemical sensor based on pencil graphite electrode and its application in the quantification of heavy metals. The sensor has a high conductive surface area, capable of producing high signals, making it more suitable for electrochemical analysis compared to unmodified electrodes.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Ahlam Zaid Alkilani, Sukaina Nimrawi, Nusaiba K. Al-nemrawi, Jehad Nasereddin
Summary: Transdermal drug delivery using biodegradable polymeric nanoparticles loaded in hydrogel microneedles showed promising results for sustained delivery of amlodipine besylate. Different formulations of nanoparticles were investigated for their characteristics and drug release kinetics, demonstrating the potential of this system for controlled transdermal drug delivery.
DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY
(2022)
Article
Chemistry, Analytical
Cesar G. Gomez, Omar E. Linarez Perez, Lucia B. Avalle, Mariana I. Rojas
Summary: This study presents a comprehensive analysis of the morphology and electrochemical properties of graphite carbon nitride/highly oriented pyrolytic graphite electrode surface for hydrogen peroxide reduction reaction. Results indicate that graphite carbon nitride is a valuable electroactive material that can enhance the electro-activity of other cheaper carbonaceous substrates.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Pharmacology & Pharmacy
Esra Pezik, Tugba Gulsun, Selma Sahin, Imran Vural
Summary: This study aimed to prepare pullulan-based orally disintegrating films (ODFs) containing amlodipine besylate, and various characterization studies were conducted on the optimized formulation, which showed appropriate morphological and mechanical properties and rapid disintegration and dissolution. Cytotoxicity and permeability studies on human epithelial colorectal adenocarcinoma (Caco-2) cell line indicated no significant toxic effects from the ODFs. Overall, the pullulan-based amlodipine besylate ODFs were recommended for enhanced ease of administration and patient compliance.
EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
(2021)
Article
Chemistry, Multidisciplinary
Fei Zhang, Danhui Ren, Lingqi Huang, Yinhang Zhang, Yuxuan Sun, Dan Liu, Qi Zhang, Wei Feng, Qingbin Zheng
Summary: Stretchable conductors with stable electrical conductivity under harsh mechanical deformations have been developed using 3D interconnected conductive graphite nanoplatelet welded carbon nanotube networks. The unique welding mechanism using GNPs enables high electrical conductivity, high stretchability, and long-term stability, allowing for applications in a myriad of new applications.
ADVANCED FUNCTIONAL MATERIALS
(2021)
Article
Chemistry, Analytical
Aftab Ahmed Khand, Saeed Ahmed Lakho, Aneela Tahira, Mansoor Ahmed, Umair Aftab, Muhammad Ishaq Abro, Awais Ahmed Juno, Ayman Nafady, Zafar Hussain Ibupoto
Summary: The study synthesized nickel oxide (NiO) nanostructures using potassium dichromate as a surface modifying agent by hydrothermal method, which showed high activity for the oxidation of ADB besylate (ADB). The morphology and unit cell structure of NiO were investigated using SEM and XRD techniques, with a well-resolved oxidation peak identified at 0.70 V in the CV characterization. The NiO nanostructures exhibited a linear range from 20-90 nM with a LOD of 2.125 nM and a LOQ of 4.08 nM, showing potential for monitoring ADB concentrations in pharmaceutical products.
Article
Chemistry, Analytical
Negar Mohammadi, Manochehr Bahmaei, Amirabdolah Mehrdad Sharif
Summary: In this study, simultaneous electrochemical measurement of Acetaminophen, Tyrosine, and Codeine was discussed for the first time. A CuZnO-Fe3O4/rGO nanocomposite was prepared and successfully applied for the amendment of a glassy carbon electrode surface. The sensor demonstrated good performance in monitoring analytes in urine and human blood plasma, showing good agreement with results obtained using the HPLC method.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2021)
Article
Spectroscopy
Amira H. Kamal, Sherin F. Hammad, Doaa N. Kamel
Summary: Two simple chemometric spectrophotometric methods, isosbestic point method and dual wavelength method, were developed for the determination of metoprolol succinate and amlodipine besylate in binary mixtures. The results obtained from the developed methods showed good agreement with those from a reported method.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Inorganic & Nuclear
Rahul B. Pujari, Abhishek C. Lokhande, Abhijeet R. Shelke, Shital B. Kale, Dong-Weon Lee, Chandrakant D. Lokhande
Summary: In this study, crystalline, porous, and nanostructured MnS2 and MnS2/carbon nanotube electrodes were prepared using dip dry and successive ionic layer adsorption and reaction (SILAR) methods at room temperature. MnS2/CNT exhibited superior charge storage performance in Na2SO4 electrolyte, showing a high specific capacitance and excellent capacitance retention for continuous charge-discharge cycles. The improvement in electrochemical charge storage of MnS2/CNT was attributed to reduced electron transfer path and low equivalent series resistance (ESR) in Na2SO4.
SOLID STATE SCIENCES
(2021)
Article
Pharmacology & Pharmacy
Jing Yu, Yan Ma, Xin He, Xiao Na Long, Jun Xu, Lei Wang, Zhi-Peng Feng, Hong-Ying Peng
Summary: The objective of this study was to investigate the effects of irbesartan and amlodipine besylate tablets on the intestinal microflora of rats with hypertensive renal damage. The results showed that irbesartan was better than amlodipine besylate at improving the diversity of the intestinal flora in these rats.
FRONTIERS IN PHARMACOLOGY
(2022)
Article
Chemistry, Analytical
Mitsuhiro Seki, Ryotaro Wada, Hitoshi Muguruma
Summary: This study investigates the intramolecular cyclization reactions of catecholamines in the ECE process, revealing that the cyclization rate is pH-dependent and follows a specific order for different types of catecholamines. The electrochemical behavior is verified by analyzing the change in cathodic peak intensity due to the reduction of catecholamine-o-quinone. This work contributes to a deeper understanding of catecholamines and the development of novel strategies for electrochemical sensing.
JOURNAL OF ELECTROANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Multidisciplinary
Xi Li, Bo Luo, Min Liao, Abdullah Mohamed
Summary: In this study, hexagonal NiO nanodisks fabricated by hydrothermal protocol were used to successfully determine the presence of Fentanyl. The electrochemical sensor, modified with multiwall carbon nanotubes (MWCNTs) and HG-NiO-NDs, showed potent electrochemical behavior due to the synergism of these materials. By optimizing the conditions, including pH value, concentration, and sweep rate of supporting electrolytes, the developed electrode exhibited admirable performance in measuring Fentanyl. The results indicated the ability of the modified electrode to fabricate non-enzymatic Fentanyl sensor applications.
FRONTIERS IN CHEMISTRY
(2022)
Review
Chemistry, Analytical
Neeta Thapliyal, Rajshekhar V. Karpoormath, Rajendra N. Goyal
ANALYTICA CHIMICA ACTA
(2015)
Article
Chemistry, Analytical
Himanshu Chasta, Rajendra N. Goyal
Article
Electrochemistry
Pankaj Gupta, Rajendra N. Goyal
ELECTROCHIMICA ACTA
(2015)
Article
Electrochemistry
Neeraj Kumar, Rosy, Rajendra N. Goyal
ELECTROCHIMICA ACTA
(2016)
Article
Electrochemistry
Mamta Raj, Pankaj Gupta, Rajendra N. Goyal
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2016)
Article
Chemistry, Analytical
Rosy, Pankaj Gupta, Rajendra N. Goyal
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Article
Chemistry, Analytical
Rosy, Mamta Raj, Rajendra N. Goyal
SENSORS AND ACTUATORS B-CHEMICAL
(2016)
Review
Chemistry, Multidisciplinary
Neeta Thapliyal, Tirivashe E. Chiwunze, Rajshekhar Karpoormath, Rajendra N. Goyal, Harun Patel, Srinivasulu Cherukupalli
Article
Biophysics
Sunita Bishnoi, Ashutosh Sharma, Rahul Singhal, Rajendra N. Goyal
BIOSENSORS & BIOELECTRONICS
(2020)
Article
Chemistry, Analytical
Sunita Bishnoi, Ashutosh Sharma, Rahul Singhal, Pankaj Gupta, Rajendra N. Goyal
Summary: In view of the increase in breast cancer cases, a new electrochemical sensing method for detecting the carcinogenic pesticide chlorpyrifos in breast milk has been proposed. The method offers high sensitivity, stability, and is useful for cancer hospitals, pesticide industries, and environmental toxicity-related studies.
Article
Electrochemistry
Jay Gautam, Mamta Raj, Rajendra N. Goyal
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2020)
Article
Electrochemistry
Neeraj Kumar, Rajendra N. Goyal, Munetaka Oyama
JOURNAL OF THE ELECTROCHEMICAL SOCIETY
(2019)
Article
Chemistry, Multidisciplinary
Pankaj Gupta, Munetaka Oyama, Rajendra N. Goyal
Article
Chemistry, Multidisciplinary
Rosy, Rajendra N. Goyal, Yoon-Bo Shim
Article
Chemistry, Multidisciplinary
Neeta Thapliyal, Nadir S. E. Osman, Harun Patel, Rajshekhar Karpoormath, Rajendra N. Goyal, Thomas Moyo, Rajkumar Patel
Article
Biochemistry & Molecular Biology
Priyanga Kumar, Noel Nesakumar, Jayashree Gopal, Sakthivel Sivasubramanian, Srinivasan Vedantham, John Bosco Balaguru Rayappan
Summary: This study developed an electrochemical biosensor for measuring MG levels in the plasma of type-2 diabetes mellitus patients. The biosensor showed a wide linear concentration range, high sensitivity, and a 90% correlation with ELISA data. It also exhibited a significant correlation with HbA1c and fasting plasma glucose levels.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Cristina Tortolini, Valeria Gigli, Antonio Angeloni, Federico Tasca, Nguyen T. K. Thanh, Riccarda Antiochia
Summary: The development of a novel voltammetric immunosensor for the detection of salivary MMP-8 at the point-of-care is described. The sensor showed good performance and comparable results to the conventional ELISA method when tested in real saliva samples. This biosensor is single-use, cost-effective, and requires a small quantity of test medium and a short preparation time.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Rimsha B. Jamal, Ulrich Bay Gosewinkel, Elena E. Ferapontova
Summary: Pathogen-triggered infections are a severe global threat to human health. Researchers have developed a fast and inexpensive electrocatalytic aptamer assay for the specific and ultrasensitive detection of E. coli, allowing for timely treatment and prevention. The method is fast, sensitive, and can be used in field and point-of-care applications for analysis of bacteria in the human environment.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Miao Liu, Yuwei Wang, Shanshan Tang, Wei Wang, Axin Liang, Aiqin Luo
Summary: An unlabeled ratiometric molecular imprinted electrochemiluminescence sensor was developed for the determination of trace uric acid using MXene@NaAsc, CdSe@ZnS quantum dots, and molecularly imprinted polymer composites modified glass carbon electrode. This sensor, with easy preparation, great selectivity, and excellent sensitivity, successfully detected uric acid in human serum.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Charlotte Da Silva, Camille Lamarche, Carole Pichereaux, Emmanuelle Mouton-Barbosa, Gauthier Demol, Sebastien Boisne, Etienne Dague, Odile Burlet-Schiltz, Flavien Pillet, Marie-Pierre Rols
Summary: Low-energy electron beams (LEEB) are a safe and practical sterilization solution for industrial applications. To address the limitations of LEEB, we developed a low-energy pulsed electron beam generator (LEPEB) that can effectively and efficiently eradicate bacteria in a wide range of industrial applications.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Daniel Dobrovodsky, Ales Danhel, Daniel Renciuk, Jean-Louis Mergny, Miroslav Fojta
Summary: In this study, N-methyl mesoporphyrin IX (NMM) was utilized as a voltammetric probe for the electrochemical detection of G4s. The detection of NMM was achieved by cyclic voltammetry on a hanging mercury drop electrode (HMDE) with a limit of detection (LOD) of 40 nM. The reduction signal of NMM was found to be significantly higher when G4 oligodeoxynucleotides (G4 ODNs) were present compared to single- or double-stranded ODNs or unfolded ODNs capable of forming G4s. Gradual transition from unstructured single strand to G4, induced by increasing concentrations of the G4 stabilizing K+ ions, was detected for the first time using electrochemical methods. Circular dichroism spectroscopy provided support for the obtained results. This work expands on the utilization of electrochemical probes for DNA secondary structure recognition and offers a proof of principle for the development of novel electroanalytical methods for nucleic acid structure studies.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Mengjiao Zhu, Yu Liu, Meiyue Wang, Tao Liu, Zhenyu Chu, Wanqin Jin
Summary: Early rapid diagnosis of COVID-19 is crucial for reducing the risk of severe symptoms and loss of lung function. Researchers have proposed an ultrafast and ultrasensitive DNA sensor that can accurately detect the virus in a short period of time, with outstanding selectivity.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Fatima-Zahra Ait-Itto, James A. Behan, Mathieu Martinez, Frederic Barriere
Summary: This study investigated the feasibility of using ancient marine sediments as inoculum for bioanode development in microbial fuel cells (MFC). The results showed the presence of two exoelectrogenic bacterial genera in these iron-rich sediments and confirmed that the development of the bioanode derived from the native microbiota. This study has important implications for understanding the role of these bacteria in broader paleoenvironmental phenomena.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Issa Fall, Bastien Doumeche, Sofiene Abdellaoui, Caroline Remond, Harivony Rakotoarivonina, Marjorie Ochs
Summary: This article presents a novel electrochemical tool based on lignin-coated paper electrodes for the detection and characterization of ligninolytic activity. The suitability of this method has been demonstrated using a catalaseperoxidase isolated from Thermobacillus xylanilyticus.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Chenyi Zhuo, Dehong Yu, Jiuying Cui, Zichun Song, Qianli Tang, Xianjiu Liao, Zhao Liu, Ning Xin, Lu Lou, Fenglei Gao
Summary: A label-free detection strategy for quantification of Apolipoprotein A4 (Apo-A4) has been developed based on rolling circle amplification (RCA) and proximity hybridization-induced DNAzyme-driven bipedal DNA walker. This method shows high sensitivity and selectivity for a wide range of protein targets.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Niloufar Fattahi, Jeffrey Reed, Evan Heronemus, Priyasha Fernando, Ryan Hansen, Prathap Parameswaran
Summary: In this study, polyethylene glycol hydrogels were developed as protective coatings for electroactive biofilms, improving their viability under low resource conditions and ammonia-N shocks.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Xiaopeng Hou, Qiongyi Cheng, Hui Wang
Summary: A self-cleaning paper-based microfluidic biosensor was developed using hydrophobic paper decorated with polymeric octadecyl trichlorosilane. The biosensor showed improved performance and could effectively measure the concentration of copper ions in livestock feed and manure.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Yanling Zhang, Jie Wang, Min Liu, Yun Ni, Yao Yue, Dawei He, Ruijiang Liu
Summary: An innovative electrochemical biosensor has been developed for sensitive detection of HER2 protein, an important tumor marker for breast cancer diagnosis and treatment evaluation. The biosensor utilizes specific recognition probes and nanomaterials, along with a unique sensing strategy, to achieve ultra-low detection limit and demonstrate excellent selectivity, reproducibility, and stability.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Humayun Amir, Vasanth Subramanian, Sundaram Sornambikai, Nagamony Ponpandian, Chinnusamy Viswanathan
Summary: In this study, the electrochemical detection of breast cancer biomarker HER2 was successfully achieved using the N-CQDs/GS as the detector. The BSA-modified HER2 Antibody/N-CQDs/GS immunoelectrode preserved excellent activity for the biosensor, while the GS electrode provided high stability and conductivity. The method exhibited a low detection limit and optimal specificity, stability, and reproducibility for detecting HER-2 protein in untreated blood samples from breast cancer patients.
BIOELECTROCHEMISTRY
(2024)
Article
Biochemistry & Molecular Biology
Ilona Uzieliene, Anton Popov, Raminta Vaiciuleviciute, Gailute Kirdaite, Eiva Bernotiene, Almira Ramanaviciene
Summary: This review discusses the application of polypyrrole (Ppy), an electroconductive polymer, in cell culture experiments with electrical stimulation (ES) and its potential for tissue regeneration. Ppy can direct ES to cells and stimulate differentiation towards different cell lineages. Different types of Ppy materials and their combination with active molecules are explored.
BIOELECTROCHEMISTRY
(2024)