Genome-Based Bacterial Vaccines: Current State and Future Outlook

Immunogenicity and safety of an investigational multicomponent, recombinant, meningococcal serogroup B vaccine (4CMenB) administered concomitantly with routine infant and child vaccinations: results of two randomised trials

(2013) Timo Vesikari et al.   LANCET

Predicted strain coverage of a meningococcal multicomponent vaccine (4CMenB) in Europe: a qualitative and quantitative assessment

(2013) Ulrich Vogel et al.   LANCET INFECTIOUS DISEASES

The genomes of four tapeworm species reveal adaptations to parasitism

(2013) Isheng J. Tsai et al.   NATURE

A Reverse Vaccinology Approach for the Identification of Potential Vaccine Candidates from Leishmania spp

(2012) Lijo John et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

Interlaboratory Standardization of the Sandwich Enzyme-Linked Immunosorbent Assay Designed for MATS, a Rapid, Reproducible Method for Estimating the Strain Coverage of Investigational Vaccines

(2012) Brian D. Plikaytis et al.   Clinical and Vaccine Immunology

Burden of disease from cryptosporidiosis

(2012) Debbie-Ann T. Shirley et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Prevention of group B streptococcal neonatal disease revisited. The DEVANI European project

(2012) J. Rodriguez-Granger et al.   EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES

Immunogenicity and Tolerability of Recombinant Serogroup B Meningococcal Vaccine Administered With or Without Routine Infant Vaccinations According to Different Immunization Schedules

(2012) Nicoletta Gossger et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Prevention of serogroup B meningococcal disease

(2012) David S Stephens   LANCET

Immunogenicity and tolerability of a multicomponent meningococcal serogroup B (4CMenB) vaccine in healthy adolescents in Chile: a phase 2b/3 randomised, observer-blind, placebo-controlled study

(2012) María Elena Santolaya et al.   LANCET

The Worldwide Impact of the Seven-valent Pneumococcal Conjugate Vaccine

(2012) Sean P. Fitzwater et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

A Randomized, Controlled, Phase 1/2 Trial of a Neisseria meningitidis Serogroup B Bivalent rLP2086 Vaccine in Healthy Children and Adolescents

(2012) Michael D. Nissen et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Transcriptional Profiling of Serogroup B Neisseria meningitidis Growing in Human Blood: An Approach to Vaccine Antigen Discovery

(2012) Asa K. Hedman et al.   PLoS One

Screening of 71 P. multocida Proteins for Protective Efficacy in a Fowl Cholera Infection Model and Characterization of the Protective Antigen PlpE

(2012) Tamás Hatfaludi et al.   PLoS One

The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: Immunological, functional and structural characterization of the antigens

(2012) Davide Serruto et al.   VACCINE

A phase 3, randomized, double-blind trial comparing the safety and immunogenicity of the 7-valent and 13-valent pneumococcal conjugate vaccines, given with routine pediatric vaccinations, in healthy infants in Brazil

(2012) Lily Yin Weckx et al.   VACCINE

Edwardsiella tarda flagellar protein FlgD: A protective immunogen against edwardsiellosis

(2012) Meng Zhang et al.   VACCINE

A systematic, functional genomics, and reverse vaccinology approach to the identification of vaccine candidates in the cattle tick, Rhipicephalus microplus

(2012) Christine Maritz-Olivier et al.   Ticks and Tick-Borne Diseases

FdeC, a Novel Broadly Conserved Escherichia coli Adhesin Eliciting Protection against Urinary Tract Infections

(2012) B. Nesta et al.   mBio

Bexsero

(2012) Andrew R. Gorringe et al.   Human Vaccines & Immunotherapeutics

Computer aided subunit vaccine design against pathogenic Leptospira serovars

(2012) Amineni Umamaheswari et al.   Interdisciplinary Sciences-Computational Life Sciences

Basic research in HIV vaccinology is hampered by reductionist thinking

(2012) Marc H. V. Van Regenmortel   Frontiers in Immunology

Identification and Immunological Characterization of Three Potential Vaccinogens against Cryptosporidium Species

(2011) Patricio A. Manque et al.   Clinical and Vaccine Immunology

Neonatal group B streptococcal disease: from pathogenesis to preventive strategies

(2011) P. Melin   CLINICAL MICROBIOLOGY AND INFECTION

Next generation pneumococcal vaccines

(2011) Kristin L Moffitt et al.   CURRENT OPINION IN IMMUNOLOGY

Recombinant protein meningococcal serogroup B vaccine combined with outer membrane vesicles

(2011) Xilian Bai et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Neisseria meningitidisB vaccines

(2011) Donatella Panatto et al.   Expert Review of Vaccines

Genome-wide screening and identification of antigens for rickettsial vaccine development: 1

(2011) Guy H. Palmer et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Vaccines for Leishmaniasis: From proteome to vaccine candidates

(2011) Juliane Schroeder et al.   Human vaccines & immunotherapeutics

RrgB321, a Fusion Protein of the Three Variants of the Pneumococcal Pilus Backbone RrgB, Is ProtectiveIn Vivoand Elicits Opsonic Antibodies

(2011) Carole Harfouche et al.   INFECTION AND IMMUNITY

In silico prediction of binding of promiscuous peptides to multiple MHC class-II molecules identifies the Th1 cell epitopes from secreted and transmembrane proteins of Schistosoma japonicum in BALB/c mice

(2011) Ben Peng Zhao et al.   MICROBES AND INFECTION

The development of vaccines: how the past led to the future

(2011) Stanley A. Plotkin et al.   NATURE REVIEWS MICROBIOLOGY

Cestode genomics - progress and prospects for advancing basic and applied aspects of flatworm biology

(2011) P. D. OLSON et al.   PARASITE IMMUNOLOGY

Safety and Immunogenicity of a 13-valent Pneumococcal Conjugate Vaccine in Healthy Infants and Toddlers Given With Routine Pediatric Vaccinations in Canada

(2011) Otto G. Vanderkooi et al.   PEDIATRIC INFECTIOUS DISEASE JOURNAL

Structure-based approach to rationally design a chimeric protein for an effective vaccine against Group B Streptococcus infections

(2011) A. Nuccitelli et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rational Design of a Meningococcal Antigen Inducing Broad Protective Immunity

(2011) M. Scarselli et al.   Science Translational Medicine

Two meanings of reverse vaccinology and the empirical nature of vaccine science

(2011) Marc H.V. Van Regenmortel   VACCINE

Identification of Ehrlichia ruminantium proteins that activate cellular immune responses using a reverse vaccinology strategy

(2011) J. Liebenberg et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Transcriptome Analysis of Neisseria meningitidis in Human Whole Blood and Mutagenesis Studies Identify Virulence Factors Involved in Blood Survival

(2011) Hebert Echenique-Rivera et al.   PLoS Pathogens

Multicenter, Open‐Label, Randomized Phase II Controlled Trial of an Investigational Recombinant Meningococcal Serogroup B Vaccine With and Without Outer Membrane Vesicles, Administered in Infancy

(2010) Jamie Findlow et al.   CLINICAL INFECTIOUS DISEASES

Rational antibody-based HIV-1 vaccine design: current approaches and future directions

(2010) Laura M Walker et al.   CURRENT OPINION IN IMMUNOLOGY

Advances in the Development of Vaccines againstNeisseria meningitidis

(2010) Lionel K.K. Tan et al.   NEW ENGLAND JOURNAL OF MEDICINE

Reverse vaccinology approach identify an Echinococcus granulosus tegumental membrane protein enolase as vaccine candidate

(2010) Wenjia Gan et al.   PARASITOLOGY RESEARCH

Pooled Protein Immunization for Identification of Cell Surface Antigens in Streptococcus sanguinis

(2010) Xiuchun Ge et al.   PLoS One

Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans

(2010) Davide Serruto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Qualitative and quantitative assessment of meningococcal antigens to evaluate the potential strain coverage of protein-based vaccines

(2010) J. Donnelly et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of protective and broadly conserved vaccine antigens from the genome of extraintestinal pathogenic Escherichia coli

(2010) D. G. Moriel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro and in vivo evaluation of five low molecular weight proteins of Ehrlichia ruminantium as potential vaccine components

(2010) S.I. Sebatjane et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY

Identification of novel immunogenic proteins in pathogenic Haemophilus parasuis based on genome sequence analysis

(2010) Minhee Hong et al.   VETERINARY MICROBIOLOGY

Expert consensus for the diagnosis and treatment of cystic and alveolar echinococcosis in humans

(2009) Enrico Brunetti et al.   ACTA TROPICA

Microarray-based comparative genomic profiling of reference strains and selected Canadian field isolates of Actinobacillus pleuropneumoniae

(2009) Julien Gouré et al.   BMC GENOMICS

Immunoproteomic Analysis of the Development of Natural Immunity in Subjects Colonized by Neisseria meningitidis Reveals Potential Vaccine Candidates

(2009) J. N. Williams et al.   INFECTION AND IMMUNITY

Isolation of Human Monoclonal Antibodies That Potently Neutralize Human Cytomegalovirus Infection by Targeting Different Epitopes on the gH/gL/UL128-131A Complex

(2009) A. Macagno et al.   JOURNAL OF VIROLOGY

Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates

(2009) Katherine L O'Brien et al.   LANCET

Effect of Pneumococcal Conjugate Vaccine on Pneumococcal Meningitis

(2009) Heather E. Hsu et al.   NEW ENGLAND JOURNAL OF MEDICINE

Towards the Immunoproteome of Neisseria meningitidis

(2009) Tom A. Mendum et al.   PLoS One

Antibody Recognition of a Highly Conserved Influenza Virus Epitope

(2009) D. C. Ekiert et al.   SCIENCE

Global epidemiology of meningococcal disease

(2009) Lee H. Harrison et al.   VACCINE

Bacterial Genome Variability and Its Impact on Vaccine Design

(2008) John L. Telford   Cell Host & Microbe

Identification and Experimental Verification of Protective Antigens Against Streptococcus suis Serotype 2 Based on Genome Sequence Analysis

(2008) Lina Liu et al.   CURRENT MICROBIOLOGY

Synthetic TLR4-active Glycolipids as Vaccine Adjuvants and Stand-alone Immunotherapeutics

(2008) David Johnson   CURRENT TOPICS IN MEDICINAL CHEMISTRY

MalVac: Database of malarial vaccine candidates

(2008) Rupanjali Chaudhuri et al.   MALARIA JOURNAL

A reverse vaccinology approach to swine dysentery vaccine development

(2008) Yong Song et al.   VETERINARY MICROBIOLOGY