Investigation on critical structural motifs of ligands for triggering glucocorticoid receptor nuclear migration through molecular docking simulations

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(2016)   ChemMedChem

The discovery of potent and selective non-steroidal glucocorticoid receptor modulators, suitable for inhalation

(2014) Karl Edman et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Structures and mechanism for the design of highly potent glucocorticoids

(2014) Yuanzheng He et al.   CELL RESEARCH

Glucocorticoid Receptor Modulators Informed by Crystallography Lead to a New Rationale for Receptor Selectivity, Function, and Implications for Structure-Based Design

(2014) Matthew W. Carson et al.   JOURNAL OF MEDICINAL CHEMISTRY

Dual Role for Glucocorticoids in Cardiomyocyte Hypertrophy and Apoptosis

(2012) Rongqin Ren et al.   ENDOCRINOLOGY

Antcin A, a steroid-like compound from Antrodia camphorata, exerts anti-inflammatory effect via mimicking glucocorticoids

(2011) Yi-ching Chen et al.   ACTA PHARMACOLOGICA SINICA

Maps and legends: The quest for dissociated ligands of the glucocorticoid receptor

(2011) Andrew R. Clark et al.   PHARMACOLOGY & THERAPEUTICS

Virtual Screening for the Identification of Novel Nonsteroidal Glucocorticoid Modulators

(2010) Valeria Onnis et al.   JOURNAL OF MEDICINAL CHEMISTRY

Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids

(2010) Diego M. Presman et al.   PLoS One

Rational ligand-based virtual screening and structure–activity relationship studies in the ligand-binding domain of the glucocorticoid receptor-α

(2009) Valeria Onnis et al.   Future Medicinal Chemistry

Molecular Switch in the Glucocorticoid Receptor: Active and Passive Antagonist Conformations

(2009) Guillaume A. Schoch et al.   JOURNAL OF MOLECULAR BIOLOGY

Design and x-ray crystal structures of high-potency nonsteroidal glucocorticoid agonists exploiting a novel binding site on the receptor

(2009) K. Biggadike et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The first X-ray crystal structure of the glucocorticoid receptor bound to a non-steroidal agonist

(2008) Kevin P. Madauss et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Combining 3D-QSAR, docking, molecular dynamics and MM/PBSA methods to predict binding modes for nonsteroidal selective modulator to glucocorticoid receptor

(2008) Yong Xu et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

X-ray Crystal Structure of the Novel Enhanced-Affinity Glucocorticoid Agonist Fluticasone Furoate in the Glucocorticoid Receptor−Ligand Binding Domain⊥

(2008) Keith Biggadike et al.   JOURNAL OF MEDICINAL CHEMISTRY

Induced-fit docking of mometasone furoate and further evidence for glucocorticoid receptor 17α pocket flexibility

(2008) Hongwu Wang et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

The role and regulation of 11β-hydroxysteroid dehydrogenase type 1 in the inflammatory response

(2008) Karen E. Chapman et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Glucocorticoid Regulation of the Promoter of 11β-Hydroxysteroid Dehydrogenase Type 1 Is Indirect and Requires CCAAT/Enhancer-Binding Protein-β

(2008) Shuji Sai et al.   MOLECULAR ENDOCRINOLOGY

Minireview: Latest Perspectives on Antiinflammatory Actions of Glucocorticoids

(2008) Karolien De Bosscher et al.   MOLECULAR ENDOCRINOLOGY

Glucocorticoid receptor binding: A biphasic dependence on molecular size as revealed by the bilinear LinBiExp model

(2007) Peter Buchwald   STEROIDS