13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1

Review of methods to assign the nuclear magnetic resonance peaks of reductively methylated proteins

(2014) Kevin J. Roberson et al.   ANALYTICAL BIOCHEMISTRY

Bringing Dynamic Molecular Machines into Focus by Methyl-TROSY NMR

(2014) Rina Rosenzweig et al.   Annual Review of Biochemistry

TROSY NMR with a 52 kDa sugar transport protein and the binding of a small-molecule inhibitor

(2014) Arnout P. Kalverda et al.   MOLECULAR MEMBRANE BIOLOGY

Conformational changes required for H+/Cl− exchange mediated by a CLC transporter

(2014) Daniel Basilio et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of sugar-bound LacY

(2014) Hemant Kumar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupled ion binding and structural transitions along the transport cycle of glutamate transporters

(2014) Grégory Verdon et al.   eLife

NMR Spectroscopy of Soluble Protein Complexes at One Mega-Dalton and Beyond

(2013) Andi Mainz et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Common Folds and Transport Mechanisms of Secondary Active Transporters

(2013) Yigong Shi   Annual Review of Biophysics

19F NMR: a valuable tool for studying biological events

(2013) Han Chen et al.   CHEMICAL SOCIETY REVIEWS

Molecular mechanism of the Escherichia coli maltose transporter

(2013) Jue Chen   CURRENT OPINION IN STRUCTURAL BIOLOGY

Investigation of lysine side chain interactions of interleukin-8 with heparin and other glycosaminoglycans studied by a methylation-NMR approach

(2013) K. Mobius et al.   GLYCOBIOLOGY

Differential Effects of Mutations on the Transport Properties of the Na+/H+Antiporter NhaA fromEscherichia coli

(2013) Thomas Mager et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Application of Reductive 13C-Methylation of Lysines to Enhance the Sensitivity of Conventional NMR Methods

(2013) Tanmay Chavan et al.   MOLECULES

Fluoride-dependent interruption of the transport cycle of a CLC Cl−/H+ antiporter

(2013) Hyun-Ho Lim et al.   Nature Chemical Biology

Structural and mechanistic insights into prokaryotic energy-coupling factor transporters

(2013) Dirk J. Slotboom   NATURE REVIEWS MICROBIOLOGY

Water access points and hydration pathways in CLC H+/Cl−transporters

(2013) Wei Han et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurotransmitter Transporters: Structure Meets Function

(2013) Paul J. Focke et al.   STRUCTURE

Structural advances for the major facilitator superfamily (MFS) transporters

(2013) Nieng Yan   TRENDS IN BIOCHEMICAL SCIENCES

Molecular Dynamics Investigation of Cl− and Water Transport through a Eukaryotic CLC Transporter

(2012) Mary Hongying Cheng et al.   BIOPHYSICAL JOURNAL

Intracellular Proton Access Mechanism of the CLC-ec1 Cl−/H+ Exchanger

(2012) Hyun-Ho Lim et al.   BIOPHYSICAL JOURNAL

Partial Least-Squares Functional Mode Analysis: Application to the Membrane Proteins AQP1, Aqy1, and CLC-ec1

(2012) Tatyana Krivobokova et al.   BIOPHYSICAL JOURNAL

Utilization of lysine 13C-methylation NMR for protein–protein interaction studies

(2012) Yoshikazu Hattori et al.   JOURNAL OF BIOMOLECULAR NMR

Lysine methylation strategies for characterizing protein conformations by NMR

(2012) Sacha Thierry Larda et al.   JOURNAL OF BIOMOLECULAR NMR

X-ray structures of LeuT in substrate-free outward-open and apo inward-open states

(2012) Harini Krishnamurthy et al.   NATURE

New frontiers and developing applications in 19F NMR

(2012) Jian-Xin Yu et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Intracellular Proton Access in a Cl−/H+ Antiporter

(2012) Hyun-Ho Lim et al.   PLOS BIOLOGY

Lysosomal Acidification Mechanisms

(2011) Joseph A. Mindell   Annual Review of Physiology

The Coupled Proton Transport in the ClC-ec1 Cl−/H+ Antiporter

(2011) Yong Zhang et al.   BIOPHYSICAL JOURNAL

Solution NMR study of integral membrane proteins

(2011) CongBao Kang et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Site-Directed Methyl Group Labeling as an NMR Probe of Structure and Dynamics in Supramolecular Protein Systems: Applications to the Proteasome and to the ClpP Protease

(2011) Tomasz L. Religa et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Substrate-modulated gating dynamics in a Na+-coupled neurotransmitter transporter homologue

(2011) Yongfang Zhao et al.   NATURE

Current applications of 19F NMR to studies of protein structure and dynamics

(2011) Julianne L. Kitevski-LeBlanc et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Structure of a Slow CLC Cl−/H+Antiporter from a Cyanobacterium

(2010) Hariharan Jayaram et al.   BIOCHEMISTRY

The structural basis of secondary active transport mechanisms

(2010) Lucy R. Forrest et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

CLC channels and transporters: Proteins with borderline personalities

(2010) Alessio Accardi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Secondary Water Pore Formation for Proton Transport in a ClC Exchanger Revealed by an Atomistic Molecular-Dynamics Simulation

(2010) Youn Jo Ko et al.   BIOPHYSICAL JOURNAL

Antiport Mechanism for Cl−/H+ in ClC-ec1 from Normal-Mode Analysis

(2010) Gennady V. Miloshevsky et al.   BIOPHYSICAL JOURNAL

Optimal methyl labeling for studies of supra-molecular systems

(2010) Tomasz L. Religa et al.   JOURNAL OF BIOMOLECULAR NMR

Conformational dependence of 13C shielding and coupling constants for methionine methyl groups

(2010) Glenn L. Butterfoss et al.   JOURNAL OF BIOMOLECULAR NMR

Design, function and structure of a monomeric ClC transporter

(2010) Janice L. Robertson et al.   NATURE

Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor

(2010) Michael P. Bokoch et al.   NATURE

Ion/substrate-dependent conformational dynamics of a bacterial homolog of neurotransmitter:sodium symporters

(2010) Derek P Claxton et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Unnatural amino acid packing mutants of Escherichia coli thioredoxin produced by combined mutagenesis/chemical modification techniques

(2010) R. Wynn et al.   PROTEIN SCIENCE

Structure of a Eukaryotic CLC Transporter Defines an Intermediate State in the Transport Cycle

(2010) Liang Feng et al.   SCIENCE

Dynamic Regulation of Archaeal Proteasome Gate Opening As Studied by TROSY NMR

(2010) T. L. Religa et al.   SCIENCE

Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR

(2009) Shelley M Elvington et al.   EMBO JOURNAL

Intracellular Proton-Transfer Mutants in a CLC Cl−/H+Exchanger

(2009) Hyun-Ho Lim et al.   JOURNAL OF GENERAL PHYSIOLOGY

Alternating Access in Maltose Transporter Mediated by Rigid-Body Rotations

(2009) Dheeraj Khare et al.   MOLECULAR CELL

The Rocking Bundle: A Mechanism for Ion-Coupled Solute Flux by Symmetrical Transporters

(2009) Lucy R. Forrest et al.   PHYSIOLOGY

Recent advances in the application of solution NMR spectroscopy to multi-span integral membrane proteins

(2009) Hak Jun Kim et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Ins and Outs of Major Facilitator Superfamily Antiporters

(2008) Christopher J. Law et al.   Annual Review of Microbiology

Insights into the ClC-4 Transport Mechanism from Studies of Zn2+ Inhibition

(2008) Jeremiah D. Osteen et al.   BIOPHYSICAL JOURNAL

A simple method for amino acid selective isotope labeling of recombinant proteins in E. coli

(2008) Kit I. Tong et al.   JOURNAL OF BIOMOLECULAR NMR

Detection of protein–ligand interactions by NMR using reductive methylation of lysine residues

(2008) Sherwin J. Abraham et al.   JOURNAL OF BIOMOLECULAR NMR

The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes

(2008) Austin R. Graves et al.   NATURE

The ClC-0 chloride channel is a 'broken' Cl−/H+ antiporter

(2008) Jiří Lísal et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Proton-coupled gating in chloride channels

(2008) J. Lisal et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A provisional transport mechanism for a chloride channel-type Cl-/H+ exchanger

(2008) C. Miller et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

CLC-0 and CFTR: Chloride Channels Evolved From Transporters

(2008) Tsung-Yu Chen et al.   PHYSIOLOGICAL REVIEWS

Ion permeation through a Cl--selective channel designed from a CLC Cl-/H+ exchanger

(2008) H. Jayaram et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA