Tissue formation and tissue engineering through host cell recruitment or a potential injectable cell-based biocomposite with replicative potential: Molecular mechanisms controlling cellular senescence and the involvement of controlled transient telomerase

Telomere dysfunction induces metabolic and mitochondrial compromise

(2011) Ergün Sahin et al.   NATURE

Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria

(2011) Nilesh K. Sharma et al.   NUCLEIC ACIDS RESEARCH

A mutant telomerase defective in nuclear-cytoplasmic shuttling fails to immortalize cells and is associated with mitochondrial dysfunction

(2010) Olga A. Kovalenko et al.   AGING CELL

Telomere Length is a Biomarker of Cumulative Oxidative Stress, Biologic Age, and an Independent Predictor of Survival and Therapeutic Treatment Requirement Associated With Smoking Behavior

(2010) Mark A Babizhayev et al.   AMERICAN JOURNAL OF THERAPEUTICS

hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells

(2010) I. R. Indran et al.   CANCER RESEARCH

Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent

(2010) Nicole Büchner et al.   EXPERIMENTAL GERONTOLOGY

Telomere attrition in lens epithelial cells - a target for N-acetylcarnosine therapy

(2010) Mark et al.   Frontiers in Bioscience-Landmark

Smoking and health: association between telomere length and factors impacting on human disease, quality of life and life span in a large population-based cohort under the effect of smoking duration

(2010) Mark A. Babizhayev et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

(2010) Mariela Jaskelioff et al.   NATURE

Linking functional decline of telomeres, mitochondria and stem cells during ageing

(2010) Ergün Sahin et al.   NATURE

Telomerase activity and telomere length in the colorectal polyp-carcinoma sequence

(2010) C. Valls Bautista et al.   REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS

Inflammatory networks during cellular senescence: causes and consequences

(2010) Adam Freund et al.   TRENDS IN MOLECULAR MEDICINE

Cellular senescence: unravelling complexity

(2009) João F. Passos et al.   AGE

Mitochondrial Telomerase Reverse Transcriptase Binds to and Protects Mitochondrial DNA and Function From Damage

(2009) Judith Haendeler et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

A Role for CXCR2 in Senescence, but What about in Cancer?

(2009) J. C. Acosta et al.   CANCER RESEARCH

Telomeres, histone code, and DNA damage response

(2009) S. Misri et al.   CYTOGENETIC AND GENOME RESEARCH

Telomerase modulates Wnt signalling by association with target gene chromatin

(2009) Jae-Il Park et al.   NATURE

An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA

(2009) Yoshiko Maida et al.   NATURE

Comparing effects of mTR and mTERT deletion on gene expression and DNA damage response: a critical examination of telomere length maintenance-independent roles of telomerase

(2009) Sofia L. Vidal-Cardenas et al.   NUCLEIC ACIDS RESEARCH

How Telomeres Solve the End-Protection Problem

(2009) T. de Lange   SCIENCE

How Shelterin Protects Mammalian Telomeres

(2008) Wilhelm Palm et al.   Annual Review of Genetics

The many faces of telomerase: emerging extratelomeric effects

(2008) F. Mathias Bollmann   BIOESSAYS

Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice

(2008) Antonia Tomás-Loba et al.   CELL

Oncogene-Induced Senescence Relayed by an Interleukin-Dependent Inflammatory Network

(2008) Thomas Kuilman et al.   CELL

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Actions of human telomerase beyond telomeres

(2008) Yusheng Cong et al.   CELL RESEARCH

Diversity of Fibroblasts – A Review on Implications for Skin Tissue Engineering

(2008) Sonja Veronika Nolte et al.   CELLS TISSUES ORGANS

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

(2008) S. Ahmed et al.   JOURNAL OF CELL SCIENCE

Stress-induced Premature Senescence (SIPS)

(2008) Masatoshi SUZUKI et al.   JOURNAL OF RADIATION RESEARCH

Telomerase, senescence and ageing

(2008) May Shawi et al.   MECHANISMS OF AGEING AND DEVELOPMENT

TERT promotes cellular and organismal survival independently of telomerase activity

(2008) J Lee et al.   ONCOGENE

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

(2008) Jinkuk Choi et al.   PLoS Genetics