What is “phenoptosis” and how to fight it?

Behavioral Effects Induced by Mitochondria-Targeted Antioxidant SkQ1 in Wistar and Senescence-Accelerated OXYS Rats

(2017) Natalia A. Stefanova et al.   JOURNAL OF ALZHEIMERS DISEASE

Chain-breaking antioxidant activity of reduced forms ofmitochondria-targeted quinones, a novel type of geroprotectors

(2016) Vitaly A. Roginsky et al.   Aging-US

Mitochondria-targeted antioxidant SkQ1 inhibits age-dependent involution of the thymus in normal and senescence-prone rats

(2016) Lidia A. Obukhova et al.   Aging-US

SkQ1 treatment and food restriction — two ways to retard an aging program of organisms

(2016) Vladimir P. Skulachev   Aging-US

Effects of the mitochondria-targeted antioxidant SkQ1 on lifespan of rodents

(2016) Vladimir N. Anisimov et al.   Aging-US

Phenoptosis in yeasts

(2012) E. I. Sukhanova et al.   BIOCHEMISTRY-MOSCOW

The phenoptosis problem: What is causing the death of an organism? Lessons from acute kidney injury

(2012) D. B. Zorov et al.   BIOCHEMISTRY-MOSCOW

Classification of phenoptotic phenomena

(2012) G. Libertini   BIOCHEMISTRY-MOSCOW

Testing predictions of the programmed and stochastic theories of aging: Comparison of variation in age at death, menopause, and sexual maturation

(2012) N. S. Gavrilova et al.   BIOCHEMISTRY-MOSCOW

Chronicle of recent events

(2011) V. P. Skulachev et al.   BIOCHEMISTRY-MOSCOW

On the Programmed/Non-Programmed Nature of Ageing within the Life History

(2011) Thomas B.L. Kirkwood et al.   CURRENT BIOLOGY

Mitochondrial-Targeted Plastoquinone Derivatives. Effect on Senescence and Acute Age-Related Pathologies

(2011) M. V. Skulachev et al.   CURRENT DRUG TARGETS

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

(2011) Eun Bae Kim et al.   NATURE

Abscisic Acid: Emergence of a Core Signaling Network

(2010) Sean R. Cutler et al.   Annual Review of Plant Biology

New-generation Skulachev ions exhibiting nephroprotective and neuroprotective properties

(2010) E. Y. Plotnikov et al.   BIOCHEMISTRY-MOSCOW

Novel mitochondria-targeted antioxidants, “Skulachev-Ion” derivatives, accelerate dermal wound healing in animals

(2010) I. A. Demianenko et al.   BIOCHEMISTRY-MOSCOW

Prevention of cardiolipin oxidation and fatty acid cycling as two antioxidant mechanisms of cationic derivatives of plastoquinone (SkQs)

(2010) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Mechanisms of nephroprotective effect of mitochondria-targeted antioxidants under rhabdomyolysis and ischemia/reperfusion

(2010) E.Y. Plotnikov et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury

(2010) Bartosz Szczesny et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Lifespan extension by dietary restriction is not linked to protection against somatic DNA damage in Drosophila melanogaster

(2009) Ursula Edman et al.   AGING CELL

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 2. Treatment of some ROS- and Age-related diseases (heart arrhythmia, heart infarctions, kidney ischemia, and stroke)

(2009) L. E. Bakeeva et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 4. Age-related eye disease. SkQ1 returns vision to blind animals

(2009) V. V. Neroev et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 3. Inhibitory effect of SkQ1 on tumor development from p53-deficient cells

(2009) L. S. Agapova et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 5. SkQ1 prolongs lifespan and prevents development of traits of senescence

(2009) V. N. Anisimov et al.   BIOCHEMISTRY-MOSCOW

Mitochondria-targeted plastoquinone derivatives as tools to interrupt execution of the aging program. 1. Cationic plastoquinone derivatives: Synthesis and in vitro studies

(2009) Y. N. Antonenko et al.   BIOCHEMISTRY-MOSCOW

ROS-Mediated ABA Signaling

(2009) Daeshik Cho et al.   JOURNAL OF PLANT BIOLOGY

Preparation and characterization of mouse embryonic fibroblasts with K72W mutation in somatic cytochrome C gene

(2009) I. A. Mufazalov et al.   MOLECULAR BIOLOGY

Penetrating cation/fatty acid anion pair as a mitochondria-targeted protonophore

(2009) F. F. Severin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

An attempt to prevent senescence: A mitochondrial approach

(2008) Vladimir P. Skulachev et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Effect of 40% restriction of dietary amino acids (except methionine) on mitochondrial oxidative stress and biogenesis, AIF and SIRT1 in rat liver

(2008) Pilar Caro et al.   BIOGERONTOLOGY

Flowering-time genes modulate meristem determinacy and growth form in Arabidopsis thaliana

(2008) Siegbert Melzer et al.   NATURE GENETICS