Fanconi anemia: at the Crossroads of DNA repair

The Fanconi Anemia Protein, FANCG, Binds to the ERCC1-XPF Endonuclease via Its Tetratricopeptide Repeats and the Central Domain of ERCC1

(2010) Chuan Wang et al.   BIOCHEMISTRY

Stalled replication forks: Making ends meet for recognition and stabilization

(2010) Hisao Masai et al.   BIOESSAYS

Fanconi anemia group J mutation abolishes its DNA repair function by uncoupling DNA translocation from helicase activity or disruption of protein-DNA complexes

(2010) Y. Wu et al.   BLOOD

BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair

(2010) P. J. O'Donovan et al.   CARCINOGENESIS

Deficiency of FANCD2-Associated Nuclease KIAA1018/FAN1 Sensitizes Cells to Interstrand Crosslinking Agents

(2010) Katja Kratz et al.   CELL

FANCJ/BRIP1 recruitment and regulation of FANCD2 in DNA damage responses

(2010) Fan Zhang et al.   CHROMOSOMA

FANCJ: Solving problems in DNA replication

(2010) Kevin Hiom   DNA REPAIR

The FANCM family of DNA helicases/translocases

(2010) Matthew C. Whitby   DNA REPAIR

Rad54, the motor of homologous recombination

(2010) Alexander V. Mazin et al.   DNA REPAIR

ATR activation and replication fork restart are defective in FANCM-deficient cells

(2010) Rebekka A Schwab et al.   EMBO JOURNAL

Inactivation of Palb2 gene leads to mesoderm differentiation defect and early embryonic lethality in mice

(2010) Pia Rantakari et al.   HUMAN MOLECULAR GENETICS

Ring-shaped Rad51 Paralog Protein Complexes Bind Holliday Junctions and Replication Forks as Visualized by Electron Microscopy

(2010) Sarah A. Compton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Promotion and regulation of homologous recombination by DNA helicases

(2010) Sierra Colavito et al.   METHODS

BACH1/FANCJ Acts with TopBP1 and Participates Early in DNA Replication Checkpoint Control

(2010) Zihua Gong et al.   MOLECULAR CELL

A Genetic Screen Identifies FAN1, a Fanconi Anemia-Associated Nuclease Necessary for DNA Interstrand Crosslink Repair

(2010) Agata Smogorzewska et al.   MOLECULAR CELL

Fanconi anemia and breast cancer susceptibility meet again

(2010) Ephrat Levy-Lahad   NATURE GENETICS

A new FAN of the Fanconi anaemia pathway

(2010) Katharine H. Wrighton   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A new nuclease member of the FAN club

(2010) Min Huang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ku70 Corrupts DNA Repair in the Absence of the Fanconi Anemia Pathway

(2010) P. Pace et al.   SCIENCE

FAN1 Acts with FANCI-FANCD2 to Promote DNA Interstrand Cross-Link Repair

(2010) T. Liu et al.   SCIENCE

How the Fanconi Anemia Pathway Guards the Genome

(2009) George-Lucian Moldovan et al.   Annual Review of Genetics

Structure, function and evolution of the XPD family of iron–sulfur-containing 5′→3′ DNA helicases

(2009) Malcolm F. White   BIOCHEMICAL SOCIETY TRANSACTIONS

The BRC Repeats of BRCA2 Modulate the DNA-Binding Selectivity of RAD51

(2009) Aura Carreira et al.   CELL

PALB2 Links BRCA1 and BRCA2 in the DNA-Damage Response

(2009) Feng Zhang et al.   CURRENT BIOLOGY

FANCJ Helicase Operates in the Fanconi Anemia DNA Repair Pathway and the Response to Replicational Stress

(2009) Yuliang Wu et al.   CURRENT MOLECULAR MEDICINE

FANCC suppresses short telomere-initiated telomere sister chromatid exchange

(2009) David B. Rhee et al.   HUMAN MOLECULAR GENETICS

FANCJ Uses Its Motor ATPase to Destabilize Protein-DNA Complexes, Unwind Triplexes, and Inhibit RAD51 Strand Exchange

(2009) Joshua A. Sommers et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCI Binds Branched DNA and Is Monoubiquitinated by UBE2T-FANCL

(2009) Simonne Longerich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FANCM: A Landing Pad for the Fanconi Anemia and Bloom's Syndrome Complexes

(2009) Patrizia Vinciguerra et al.   MOLECULAR CELL

FANCM Connects the Genome Instability Disorders Bloom's Syndrome and Fanconi Anemia

(2009) Andrew J. Deans et al.   MOLECULAR CELL

Cellular and molecular consequences of defective Fanconi anemia proteins in replication-coupled DNA repair: Mechanistic insights

(2009) Larry H. Thompson et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Genotype–phenotype correlations in Fanconi anemia

(2009) Kornelia Neveling et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

The BRC repeats of human BRCA2 differentially regulate RAD51 binding on single- versus double-stranded DNA to stimulate strand exchange

(2009) M. K. K. Shivji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell cycle-dependent chromatin loading of the Fanconi anemia core complex by FANCM/FAAP24

(2008) J. M. Kim et al.   BLOOD

Welcome the Family of FANCJ-like Helicases to the Block of Genome Stability Maintenance Proteins

(2008) Y. Wu et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Fanconi anemia core complex is required for efficient point mutagenesis and Rev1 foci assembly

(2008) Kanchan D. Mirchandani et al.   DNA REPAIR

FANCM of the Fanconi anemia core complex is required for both monoubiquitination and DNA repair

(2008) Yutong Xue et al.   HUMAN MOLECULAR GENETICS

Homologous recombination and maintenance of genome integrity: Cancer and aging through the prism of human RecQ helicases

(2008) Karen J. Ouyang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The Fanconi Anemia Protein FANCM Can Promote Branch Migration of Holliday Junctions and Replication Forks

(2008) Kerstin Gari et al.   MOLECULAR CELL

FANCG promotes formation of a newly identified protein complex containing BRCA2, FANCD2 and XRCC3

(2008) J B Wilson et al.   ONCOGENE

Remodeling of DNA replication structures by the branch point translocase FANCM

(2008) K. Gari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA