Proposed cytotoxic mechanisms of the saffron carotenoids crocin and crocetin on cancer cell lines

Attenuation of LDHA expression in cancer cells leads to redox-dependent alterations in cytoskeletal structure and cell migration

(2013) Robert Arseneault et al.   CANCER LETTERS

The Warburg effect in 2012

(2011) Jean-Pierre Bayley et al.   CURRENT OPINION IN ONCOLOGY

Crocetin: an Agent Derived from Saffron for Prevention and Therapy for Cancer

(2011) William G. Gutheil et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Carotenoids and apocarotenoids in cellular signaling related to cancer: A review

(2011) Yoav Sharoni et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Improvement of cytotoxic and apoptogenic properties of crocin in cancer cell lines by its nanoliposomal form

(2011) Seyed Hadi Mousavi et al.   PHARMACEUTICAL BIOLOGY

Warburg effect in chemosensitivity: Targeting lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol

(2010) Ming Zhou et al.   Molecular Cancer

Use of in vitro assays to assess the potential antiproliferative and cytotoxic effects of saffron (Crocus sativus L.) in human lung cancer cell line

(2010) Saeed Samarghandian et al.   Pharmacognosy Magazine

Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system

(2009) Karin Linnewiel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Loss of Keap1 Function Activates Nrf2 and Provides Advantages for Lung Cancer Cell Growth

(2008) T. Ohta et al.   CANCER RESEARCH

Nrf2 enhances resistance of cancer cells to chemotherapeutic drugs, the dark side of Nrf2

(2008) X.-J. Wang et al.   CARCINOGENESIS

Study of cytotoxic and apoptogenic properties of saffron extract in human cancer cell lines

(2008) Jalil Tavakkol-Afshari et al.   FOOD AND CHEMICAL TOXICOLOGY