Journal
BIOCHEMISTRY
Volume 50, Issue 6, Pages 920-931Publisher
AMER CHEMICAL SOC
DOI: 10.1021/bi101805f
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Funding
- Medical Research Council (U.K.) [G0801709, G0800142]
- Biomedical Research Centre [RG52162]
- National Institute of Allergy and Infectious Diseases
- office of the Director of the National Institutes of Health
- MRC [G0800142, G0801709] Funding Source: UKRI
- Medical Research Council [G0800142, G0801709] Funding Source: researchfish
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Retroviruses integrate into the host cell's chromosome. Accordingly, many aspects of the life cycle of retroviruses like HIV-1 are intimately linked to the functions of cellular proteins and RNAs. In this review, we discuss in brief recent genomewide screens for the identification of cellular proteins that assist HIV-1 replication in human cells. We also review findings for other cellular moieties that help or restrict the viral life cycle.
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