Extracellular vesicles: translational challenges and opportunities

Analytical Pipeline for Discovery and Verification of Glycoproteins from Plasma-Derived Extracellular Vesicles as Breast Cancer Biomarkers

(2018) I-Hsuan Chen et al.   ANALYTICAL CHEMISTRY

Acellular therapeutic approach for heart failure: in vitro production of extracellular vesicles from human cardiovascular progenitors

(2018) Nadia El Harane et al.   EUROPEAN HEART JOURNAL

Exosome-Mediated Transfer of Cancer Cell Resistance to Antiestrogen Drugs

(2018) Svetlana Semina et al.   MOLECULES

Tumor-associated macrophages-derived exosomes promote the migration of gastric cancer cells by transfer of functional Apolipoprotein E

(2018) Peiming Zheng et al.   Cell Death & Disease

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden

(2018) Adam E. Frampton et al.   Oncotarget

Effect of pH, temperature and freezing-thawing on quantity changes and cellular uptake of exosomes

(2018) Yirui Cheng et al.   Protein & Cell

Cardiac recovery via extended cell-free delivery of extracellular vesicles secreted by cardiomyocytes derived from induced pluripotent stem cells

(2018) Bohao Liu et al.   Nature Biomedical Engineering

Therapeutic application of extracellular vesicles in kidney disease: promises and challenges

(2017) Lin-Li Lv et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A nano flow cytometer for single lipid vesicle analysis

(2017) Remo Friedrich et al.   LAB ON A CHIP

Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma

(2017) Haizhen Lu et al.   Cancer Medicine

Protein and chemotherapy profiling of extracellular vesicles harvested from therapeutic induced senescent triple negative breast cancer cells

(2017) E L Kavanagh et al.   Oncogenesis

Extracellular Vesicles Arising from Apoptotic Cells in Tumors: Roles in Cancer Pathogenesis and Potential Clinical Applications

(2017) Catherine Lynch et al.   Frontiers in Immunology

Brain-derived exosomes from dementia with Lewy bodies propagate α-synuclein pathology

(2017) Jennifer Ngolab et al.   Acta Neuropathologica Communications

Nanoplasmonic quantification of tumour-derived extracellular vesicles in plasma microsamples for diagnosis and treatment monitoring

(2017) Kai Liang et al.   Nature Biomedical Engineering

Labeling Extracellular Vesicles for Nanoscale Flow Cytometry

(2017) Aizea Morales-Kastresana et al.   Scientific Reports

Age-Related Changes in Plasma Extracellular Vesicle Characteristics and Internalization by Leukocytes

(2017) Erez Eitan et al.   Scientific Reports

Introduction to Extracellular Vesicles: Biogenesis, RNA Cargo Selection, Content, Release, and Uptake

(2016) Erik R. Abels et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Exosomes secreted by cardiosphere-derived cells reduce scarring, attenuate adverse remodelling, and improve function in acute and chronic porcine myocardial infarction

(2016) Romain Gallet et al.   EUROPEAN HEART JOURNAL

Extracellular vesicles and infectious diseases: new complexity to an old story

(2016) Jeffrey S. Schorey et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular vesicle isolation and characterization: toward clinical application

(2016) Rong Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

Extracellular vesicles: masters of intercellular communication and potential clinical interventions

(2016) Jonathan M. Pitt et al.   JOURNAL OF CLINICAL INVESTIGATION

Cardiovascular progenitor–derived extracellular vesicles recapitulate the beneficial effects of their parent cells in the treatment of chronic heart failure

(2016) Anaïs Kervadec et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder

(2016) Svetlana Hakobyan et al.   Multiple Sclerosis Journal

Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes

(2016) Joanna Kowal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA Profiles in Parkinson's Disease Prefrontal Cortex

(2016) Andrew G. Hoss et al.   Frontiers in Aging Neuroscience

Plasma complement biomarkers distinguish multiple sclerosis and neuromyelitis optica spectrum disorder

(2016) Svetlana Hakobyan et al.   Multiple Sclerosis Journal

A novel affinity-based method for the isolation of highly purified extracellular vesicles

(2016) Wataru Nakai et al.   Scientific Reports

Induction of α-synuclein aggregate formation by CSF exosomes from patients with Parkinson’s disease and dementia with Lewy bodies

(2015) Anne Stuendl et al.   BRAIN

Embryonic Stem Cell-Derived Exosomes Promote Endogenous Repair Mechanisms and Enhance Cardiac Function Following Myocardial Infarction

(2015) M. Khan et al.   CIRCULATION RESEARCH

Analytical challenges of extracellular vesicle detection: A comparison of different techniques

(2015) Uta Erdbrügger et al.   CYTOMETRY PART A

Glypican-1 identifies cancer exosomes and detects early pancreatic cancer

(2015) Sonia A. Melo et al.   NATURE

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

(2015) Bruno Costa-Silva et al.   NATURE CELL BIOLOGY

Exosome Delivered Anticancer Drugs Across the Blood-Brain Barrier for Brain Cancer Therapy in Danio Rerio

(2015) Tianzhi Yang et al.   PHARMACEUTICAL RESEARCH

Extracellular vesicle-mediated transfer of processed and functional RNY5 RNA

(2015) Sudipto K. Chakrabortty et al.   RNA

Exosomes: Novel Biomarkers for Clinical Diagnosis

(2015) Jin Lin et al.   TheScientificWorldJOURNAL

Exosomes released by keratinocytes modulate melanocyte pigmentation

(2015) Alessandra Lo Cicero et al.   Nature Communications

Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation

(2015) Jae Kyu Ryu et al.   Nature Communications

Exosomes: Novel Biomarkers for Clinical Diagnosis

(2015) Jin Lin et al.   Scientific World Journal

Extracellular vesicle-mediated transfer of functional RNA in the tumor microenvironment

(2015) Kirsten Ridder et al.   OncoImmunology

Biogenesis and secretion of exosomes

(2014) Joanna Kowal et al.   CURRENT OPINION IN CELL BIOLOGY

Association of circulating endothelial microparticles with cardiometabolic risk factors in the Framingham Heart Study

(2014) Nicolas Amabile et al.   EUROPEAN HEART JOURNAL

Cardiac fibroblast–derived microRNA passenger strand-enriched exosomes mediate cardiomyocyte hypertrophy

(2014) Claudia Bang et al.   JOURNAL OF CLINICAL INVESTIGATION

Human Urinary Exosomes as Innate Immune Effectors

(2014) T. F. Hiemstra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Particle size distribution of exosomes and microvesicles determined by transmission electron microscopy, flow cytometry, nanoparticle tracking analysis, and resistive pulse sensing

(2014) E. van der Pol et al.   JOURNAL OF THROMBOSIS AND HAEMOSTASIS

MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease

(2014) L Kordelas et al.   LEUKEMIA

Label-free detection and molecular profiling of exosomes with a nano-plasmonic sensor

(2014) Hyungsoon Im et al.   NATURE BIOTECHNOLOGY

Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state

(2014) Masayuki Shimoda et al.   NATURE CELL BIOLOGY

Nanoparticle systems as tools to improve drug delivery and therapeutic efficacy

(2013) Deepa Mishra et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Extracellular vesicles: Exosomes, microvesicles, and friends

(2013) Graça Raposo et al.   JOURNAL OF CELL BIOLOGY

Biogenesis of extracellular vesicles (EV): exosomes, microvesicles, retrovirus-like vesicles, and apoptotic bodies

(2013) Johnny C. Akers et al.   JOURNAL OF NEURO-ONCOLOGY

Tumorigenicity as a clinical hurdle for pluripotent stem cell therapies

(2013) Andrew S Lee et al.   NATURE MEDICINE

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

(2012) Héctor Peinado et al.   NATURE MEDICINE

Cardiomyocyte Microvesicles Contain DNA/RNA and Convey Biological Messages to Target Cells

(2012) Anders Waldenström et al.   PLoS One

Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes

(2011) A. Montecalvo et al.   BLOOD

Interaction and uptake of exosomes by ovarian cancer cells

(2011) Cristina Escrevente et al.   BMC CANCER

Characterisation of exosomes derived from human cells by nanoparticle tracking analysis and scanning electron microscopy

(2011) Viktoriya Sokolova et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Exosome-associated Tau Is Secreted in Tauopathy Models and Is Selectively Phosphorylated in Cerebrospinal Fluid in Early Alzheimer Disease

(2011) Sudad Saman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methodology for isolation, identification and characterization of microvesicles in peripheral blood

(2011) Muthuvel Jayachandran et al.   JOURNAL OF IMMUNOLOGICAL METHODS

A Novel Nanoparticle Drug Delivery System: The Anti-inflammatory Activity of Curcumin Is Enhanced When Encapsulated in Exosomes

(2010) Dongmei Sun et al.   MOLECULAR THERAPY

The Fate of miRNA* Strand through Evolutionary Analysis: Implication for Degradation As Merely Carrier Strand or Potential Regulatory Molecule?

(2010) Li Guo et al.   PLoS One