cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP)
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Title
cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP)
Authors
Keywords
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Journal
BIOCHEMICAL SOCIETY TRANSACTIONS
Volume 42, Issue 1, Pages 89-97
Publisher
Portland Press Ltd.
Online
2014-01-23
DOI
10.1042/bst20130253
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Note: Only part of the references are listed.- Novel effects of adenosine receptors on pericellular hyaluronan matrix: implications for human smooth muscle cell phenotype and interactions with monocytes during atherosclerosis
- (2013) M. Grandoch et al. BASIC RESEARCH IN CARDIOLOGY
- Prostaglandin E2-induced intercellular adhesion molecule-1 expression is mediated by cAMP/Epac signalling modules in bEnd.3 brain endothelial cells
- (2013) Tae Yeop Park et al. BRITISH JOURNAL OF PHARMACOLOGY
- Distinct functions for Rap1 signaling in vascular morphogenesis and dysfunction
- (2013) Magdalena Chrzanowska-Wodnicka EXPERIMENTAL CELL RESEARCH
- Blocking Von Willebrand Factor for Treatment of Cutaneous Inflammation
- (2013) Carina Hillgruber et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Exchange protein activated by cAMP (Epac) induces vascular relaxation by activating Ca2+-sensitive K+channels in rat mesenteric artery
- (2013) Owain Llŷr Roberts et al. JOURNAL OF PHYSIOLOGY-LONDON
- Quantitative global phosphoproteomics of human umbilical vein endothelial cells after activation of the Rap signaling pathway
- (2013) Lars A. T. Meijer et al. Molecular BioSystems
- Epac-Inhibitors: Facts and Artefacts
- (2013) Holger Rehmann Scientific Reports
- Cyclic AMP-Rap1A signaling activates RhoA to induce α2c-adrenoceptor translocation to the cell surface of microvascular smooth muscle cells
- (2012) Selvi C. Jeyaraj et al. AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY
- Role of Epac in brain and heart
- (2012) Anne-Coline Laurent et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- 5-Cyano-6-oxo-1,6-dihydro-pyrimidines as potent antagonists targeting exchange proteins directly activated by cAMP
- (2012) Haijun Chen et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- The vascular smooth muscle cell in arterial pathology: a cell that can take on multiple roles
- (2012) P. Lacolley et al. CARDIOVASCULAR RESEARCH
- cAMP Induces Adhesion of Microvascular Smooth Muscle Cells to Fibronectin via an Epac-Mediated but PKA-independent Mechanism
- (2012) Ali H. Eid CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- The Epac-Rap1 Signaling Pathway Controls cAMP-mediated Exocytosis of Weibel-Palade Bodies in Endothelial Cells
- (2012) Kathinka W. E. M. van Hooren et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hypoxia-reoxygenation-induced endothelial barrier failure: role of RhoA, Rac1 and myosin light chain kinase
- (2012) Muhammad Aslam et al. JOURNAL OF PHYSIOLOGY-LONDON
- EPAC Null Mutation Impairs Learning and Social Interactions via Aberrant Regulation of miR-124 and Zif268 Translation
- (2012) Ying Yang et al. NEURON
- Isoform-specific antagonists of exchange proteins directly activated by cAMP
- (2012) T. Tsalkova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- PDE4 Regulates Tissue Plasminogen Activator Expression of Human Brain Microvascular Endothelial Cells
- (2012) Fan Yang et al. THROMBOSIS RESEARCH
- Ultrastructural Analysis Reveals cAMP-Dependent Enhancement of Microvascular Endothelial Barrier Functions via Rac1-Mediated Reorganization of Intercellular Junctions
- (2011) Volker Spindler et al. AMERICAN JOURNAL OF PATHOLOGY
- Intermedin (adrenomedullin2) stabilizes the endothelial barrier and antagonizes thrombin-induced barrier failure in endothelial cell monolayers
- (2011) M Aslam et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cyclic nucleotide-dependent relaxation pathways in vascular smooth muscle
- (2011) Manuel Morgado et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Epac1 and PDZ-GEF cooperate in Rap1 mediated endothelial junction control
- (2011) Willem-Jan Pannekoek et al. CELLULAR SIGNALLING
- Vascular Smooth Muscle Cell Proliferation in Restenosis
- (2011) Steven O. Marx et al. Circulation-Cardiovascular Interventions
- The cAMP-responsive Rap1 Guanine Nucleotide Exchange Factor, Epac, Induces Smooth Muscle Relaxation by Down-regulation of RhoA Activity
- (2011) Bartosz J. Zieba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- von Willebrand Factor
- (2011) Simon F. De Meyer et al. STROKE
- Epac: Defining a New Mechanism for cAMP Action
- (2010) Martijn Gloerich et al. Annual Review of Pharmacology and Toxicology
- AKAP9 regulation of microtubule dynamics promotes Epac1-induced endothelial barrier properties
- (2010) S. Sehrawat et al. BLOOD
- cAMP/PKA antagonizes thrombin-induced inactivation of endothelial myosin light chain phosphatase: role of CPI-17
- (2010) Muhammad Aslam et al. CARDIOVASCULAR RESEARCH
- Myosin light chain kinase in microvascular endothelial barrier function
- (2010) Q. Shen et al. CARDIOVASCULAR RESEARCH
- A2B receptors mediate the induction of early genes and inhibition of arterial smooth muscle cell proliferation via Epac
- (2010) Peter Mayer et al. CARDIOVASCULAR RESEARCH
- Cyclic AMP Phosphodiesterase 4D (PDE4D) Tethers EPAC1 in a Vascular Endothelial Cadherin (VE-Cad)-based Signaling Complex and Controls cAMP-mediated Vascular Permeability
- (2010) Sarah N. Rampersad et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epac as a novel effector of airway smooth muscle relaxation
- (2010) Sara S. Roscioni et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- PKA and Epac synergistically inhibit smooth muscle cell proliferation
- (2010) Richard C. Hewer et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Cyclic Nucleotide-Gated Channels Contribute to Thromboxane A2-Induced Contraction of Rat Small Mesenteric Arteries
- (2010) Yuk Ki Leung et al. PLoS One
- The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function
- (2009) Maria Grandoch et al. BRITISH JOURNAL OF PHARMACOLOGY
- Selective inhibition of cytokine-activated extracellular signal-regulated kinase by cyclic AMP via Epac1-dependent induction of suppressor of cytokine signalling-3
- (2009) Hayley D. Woolson et al. CELLULAR SIGNALLING
- The Control of Vascular Integrity by Endothelial Cell Junctions: Molecular Basis and Pathological Implications
- (2009) Elisabetta Dejana et al. DEVELOPMENTAL CELL
- Role of Rac 1 and cAMP in endothelial barrier stabilization and thrombin-induced barrier breakdown
- (2009) Y. Baumer et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function
- (2009) Manabu Niimura et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Exchange protein activated by cAMP (Epac) mediates cAMP-dependent but protein kinase A-insensitive modulation of vascular ATP-sensitive potassium channels
- (2009) Gregor I. Purves et al. JOURNAL OF PHYSIOLOGY-LONDON
- Rac GTPase is a hub for protein kinase A and Epac signaling in endothelial barrier protection by cAMP
- (2009) Anna A. Birukova et al. MICROVASCULAR RESEARCH
- Direct Spatial Control of Epac1 by Cyclic AMP
- (2009) B. Ponsioen et al. MOLECULAR AND CELLULAR BIOLOGY
- Driving Rho GTPase activity in endothelial cells regulates barrier integrity
- (2009) C. M. L. Beckers et al. THROMBOSIS AND HAEMOSTASIS
- Epac1 is upregulated during neointima formation and promotes vascular smooth muscle cell migration
- (2008) Utako Yokoyama et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Epac/Rap1 pathway regulates microvascular hyperpermeability induced by PAF in rat mesentery
- (2008) R. H. Adamson et al. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY
- Cell–cell junction formation: The role of Rap1 and Rap1 guanine nucleotide exchange factors
- (2008) Willem-Jan Pannekoek et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES
- cAMP induced Rac 1-mediated cytoskeletal reorganization in microvascular endothelium
- (2008) Y. Baumer et al. HISTOCHEMISTRY AND CELL BIOLOGY
- Identification of CCAAT/Enhancer-binding Proteins as Exchange Protein Activated by cAMP-activated Transcription Factors That Mediate the Induction of the SOCS-3 Gene
- (2008) Stephen J. Yarwood et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Epinephrine-induced Ca2+ influx in vascular endothelial cells is mediated by CNGA2 channels
- (2008) Bing Shen et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- The role of cytoskeleton in the regulation of vascular endothelial barrier function
- (2008) Natalia V. Bogatcheva et al. MICROVASCULAR RESEARCH
- The actin cytoskeleton in endothelial cell phenotypes
- (2008) Nutan Prasain et al. MICROVASCULAR RESEARCH
- Role of Epac1, an Exchange Factor for Rap GTPases, in Endothelial Microtubule Dynamics and Barrier Function
- (2008) Seema Sehrawat et al. MOLECULAR BIOLOGY OF THE CELL
- Structure of Epac2 in complex with a cyclic AMP analogue and RAP1B
- (2008) Holger Rehmann et al. NATURE
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