Imaging tumour heterogeneity of the consequences of a PKCα–substrate interaction in breast cancer patients

Talin regulates moesin–NHE-1 recruitment to invadopodia and promotes mammary tumor metastasis

(2014) Brian T. Beaty et al.   JOURNAL OF CELL BIOLOGY

Taxonomy of breast cancer based on normal cell phenotype predicts outcome

(2014) Sandro Santagata et al.   JOURNAL OF CLINICAL INVESTIGATION

Protein Kinase C α Is a Central Signaling Node and Therapeutic Target for Breast Cancer Stem Cells

(2013) Wai Leong Tam et al.   CANCER CELL

Tumour heterogeneity and immune-modulation

(2013) Mariam Jamal-Hanjani et al.   CURRENT OPINION IN PHARMACOLOGY

The Gray Institute ‘open’ high-content, fluorescence lifetime microscopes

(2013) P.R. BARBER et al.   JOURNAL OF MICROSCOPY

The shaping and functional consequences of the microRNA landscape in breast cancer

(2013) Heidi Dvinge et al.   NATURE

The causes and consequences of genetic heterogeneity in cancer evolution

(2013) Rebecca A. Burrell et al.   NATURE

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications

(2013) Elza C de Bruin et al.   Genome Medicine

Atypical ezrin localization as a marker of locally advanced breast cancer

(2012) Alan A. Arslan et al.   BREAST CANCER RESEARCH AND TREATMENT

Activation of Ezrin/Radixin/Moesin Mediates Attractive Growth Cone Guidance through Regulation of Growth Cone Actin and Adhesion Receptors

(2012) B. M. Marsick et al.   JOURNAL OF NEUROSCIENCE

Curcumin suppresses the TPA-induced invasion through inhibition of PKCα-dependent MMP-expression in MCF-7 human breast cancer cells

(2012) Jeong-Mi Kim et al.   PHYTOMEDICINE

A Temporal Model of Cofilin Regulation and the Early Peak of Actin Barbed Ends in Invasive Tumor Cells

(2011) Nessy Tania et al.   BIOPHYSICAL JOURNAL

How Förster Resonance Energy Transfer Imaging Improves the Understanding of Protein Interaction Networks in Cancer Biology

(2011) Gilbert O. Fruhwirth et al.   CHEMPHYSCHEM

Protein Kinase Cα Promotes Cell Migration through a PDZ-Dependent Interaction with its Novel Substrate Discs Large Homolog 1 (DLG1)

(2011) Audrey K. O'Neill et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nodal Status and Clinical Outcomes in a Large Cohort of Patients With Triple-Negative Breast Cancer

(2011) Leonel F. Hernandez-Aya et al.   JOURNAL OF CLINICAL ONCOLOGY

Effect of Very Small Tumor Size on Cancer-Specific Mortality in Node-Positive Breast Cancer

(2011) Jennifer Y. Wo et al.   JOURNAL OF CLINICAL ONCOLOGY

17β-Estradiol Enhances Breast Cancer Cell Motility and Invasion via Extra-Nuclear Activation of Actin-Binding Protein Ezrin

(2011) Shuhui Zheng et al.   PLoS One

Sustained inhibition of PKCα reduces intravasation and lung seeding during mammary tumor metastasis in an in vivo mouse model

(2010) J Kim et al.   ONCOGENE

Subtyping of Breast Cancer by Immunohistochemistry to Investigate a Relationship between Subtype and Short and Long Term Survival: A Collaborative Analysis of Data for 10,159 Cases from 12 Studies

(2010) Fiona M. Blows et al.   PLOS MEDICINE

Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2009

(2009) A. Goldhirsch et al.   ANNALS OF ONCOLOGY

A common cofilin activity cycle in invasive tumor cells and inflammatory cells

(2009) J. van Rheenen et al.   JOURNAL OF CELL SCIENCE

Integrating Receptor Signal Inputs That Influence Small Rho GTPase Activation Dynamics at the Immunological Synapse

(2009) K. Makrogianneli et al.   MOLECULAR AND CELLULAR BIOLOGY

The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress

(2009) Joanna R. Morris et al.   NATURE

Dynamic modularity in protein interaction networks predicts breast cancer outcome

(2009) Ian W Taylor et al.   NATURE BIOTECHNOLOGY

The potential of optical proteomic technologies to individualize prognosis and guide rational treatment for cancer patients

(2009) Muireann T. Kelleher et al.   Targeted Oncology