PKCη is an anti-apoptotic kinase that predicts poor prognosis in breast and lung cancer: Figure 1

Functional implications of assigned, assumed and assembled PKC structures

(2014) Mark Linch et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The C1B domains of novel PKCε and PKCη have a higher membrane binding affinity than those of the also novel PKCδ and PKCθ

(2014) Antonio L. Egea-Jiménez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Silencing of PKCη induces cycle arrest of EBV+ B lymphoma cells by upregulating expression of p38-MAPK/TAp73/GADD45α and increases susceptibility to chemotherapeutic agents

(2014) Ga Bin Park et al.   CANCER LETTERS

Upregulation of PKCη by PKCε and PDK1 involves two distinct mechanisms and promotes breast cancer cell survival

(2013) Deepanwita Pal et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Novel regulation of protein kinase C-η

(2012) Deepanwita Pal et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Protein kinase Cη, an emerging player in T-cell biology

(2012) Guo Fu et al.   CELL CYCLE

PKCη is a negative regulator of AKT inhibiting the IGF-I induced proliferation

(2012) Galit Shahaf et al.   EXPERIMENTAL CELL RESEARCH

Localization of PKC? in Cell Membranes as a Predictor for Breast Cancer Response to Treatment

(2012) Galia Karp et al.   ONKOLOGIE

Protein kinase Cη activates NF-κB in response to camptothecin-induced DNA damage

(2011) Hadas Raveh-Amit et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA damage targets PKCη to the nuclear membrane via its C1b domain

(2011) Ana Tamarkin et al.   EXPERIMENTAL CELL RESEARCH

PKCη promotes a proliferation to differentiation switch in keratinocytes via upregulation of p27Kip1 mRNA through suppression of JNK/c-Jun signaling under stress conditions

(2011) T Hara et al.   Cell Death & Disease

PKC and the control of localized signal dynamics

(2010) Carine Rosse et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

PKCη confers protection against apoptosis by inhibiting the pro-apoptotic JNK activity in MCF-7 cells

(2009) Noa Rotem-Dai et al.   EXPERIMENTAL CELL RESEARCH

Protein kinase Cε: an oncogene and emerging tumor biomarker

(2009) Michael A Gorin et al.   Molecular Cancer

Nuclear trafficking of pro-apoptotic kinases in response to DNA damage

(2008) Kiyotsugu Yoshida   TRENDS IN MOLECULAR MEDICINE