New strategies for the treatment of ovarian cancer: Figure 1

Preclinical evaluation of statins as a treatment for ovarian cancer

(2013) Elizabeth Robinson et al.   GYNECOLOGIC ONCOLOGY

Deciphering the signaling networks underlying simvastatin-induced apoptosis in human cancer cells: evidence for non-canonical activation of RhoA and Rac1 GTPases

(2013) Y Zhu et al.   Cell Death & Disease

Statins and cancer: Current and future prospects

(2012) Maja Osmak   CANCER LETTERS

Clinicopathological Features of Homologous Recombination-Deficient Epithelial Ovarian Cancers: Sensitivity to PARP Inhibitors, Platinum, and Survival

(2012) A. Mukhopadhyay et al.   CANCER RESEARCH

Antiangiogenic agents as a maintenance strategy for advanced epithelial ovarian cancer

(2012) Bradley J. Monk et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Navitoclax augments the activity of carboplatin and paclitaxel combinations in ovarian cancer cells

(2012) Vasileios A. Stamelos et al.   GYNECOLOGIC ONCOLOGY

Olaparib Maintenance Therapy in Platinum-Sensitive Relapsed Ovarian Cancer

(2012) Jonathan Ledermann et al.   NEW ENGLAND JOURNAL OF MEDICINE

Benzyl and Naphthalene Methylphosphonic Acid Inhibitors of Autotaxin with Anti-invasive and Anti-metastatic Activity

(2011) Renuka Gupte et al.   ChemMedChem

Phase I Study of Navitoclax (ABT-263), a Novel Bcl-2 Family Inhibitor, in Patients With Small-Cell Lung Cancer and Other Solid Tumors

(2011) Leena Gandhi et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II, Open-Label, Randomized, Multicenter Study Comparing the Efficacy and Safety of Olaparib, a Poly (ADP-Ribose) Polymerase Inhibitor, and Pegylated Liposomal Doxorubicin in Patients WithBRCA1orBRCA2Mutations and Recurrent Ovarian Cancer

(2011) Stan B. Kaye et al.   JOURNAL OF CLINICAL ONCOLOGY

Distinct Autophagosomal-Lysosomal Fusion Mechanism Revealed by Thapsigargin-Induced Autophagy Arrest

(2011) Ian G. Ganley et al.   MOLECULAR CELL

Inhibition of tumor growth and angiogenesis by a lysophosphatidic acid antagonist in an engineered three-dimensional lung cancer xenograft model

(2010) Xiaoyu Xu et al.   CANCER

Autotaxin delays apoptosis induced by carboplatin in ovarian cancer cells

(2010) Susanne Vidot et al.   CELLULAR SIGNALLING

Making the best of PARP inhibitors in ovarian cancer

(2010) Susana Banerjee et al.   Nature Reviews Clinical Oncology

Dysregulation of the mevalonate pathway promotes transformation

(2010) J. W. Clendening et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression of Autotaxin and Lysophosphatidic Acid Receptors Increases Mammary Tumorigenesis, Invasion, and Metastases

(2009) Shuying Liu et al.   CANCER CELL

Lysophosphatidic Acid 2 Receptor-mediated Supramolecular Complex Formation Regulates Its Antiapoptotic Effect

(2009) Shuyu E et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phase II Study of Metronomic Chemotherapy with Thalidomide, Carboplatin-Vincristine-Fluvastatin in the Treatment of Brain Stem Tumors in Children

(2008) Enrique López-Aguilar et al.   ARCHIVES OF MEDICAL RESEARCH

The 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, simvastatin, lovastatin and mevastatin inhibit proliferation and invasion of melanoma cells

(2008) Sharon A Glynn et al.   BMC CANCER

Statins induce apoptosis in ovarian cancer cells through activation of JNK and enhancement of Bim expression

(2008) Hongli Liu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Statin Induces Apoptosis and Cell Growth Arrest in Prostate Cancer Cells

(2008) A. Hoque et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Chemoembolization Combined with Pravastatin Improves Survival in Patients with Hepatocellular Carcinoma

(2008) Hannah Graf et al.   DIGESTION

Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells

(2008) Hang Xiao et al.   INTERNATIONAL JOURNAL OF CANCER

Autotaxin protects MCF-7 breast cancer and MDA-MB-435 melanoma cells against Taxol-induced apoptosis

(2008) N Samadi et al.   ONCOGENE