Allosteric linkers in cAMP signalling

Signaling through dynamic linkers as revealed by PKA

(2013) M. Akimoto et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Projection Analysis of NMR Chemical Shifts Reveals Extended EPAC Autoinhibition Determinants

(2012) Rajeevan Selvaratnam et al.   BIOPHYSICAL JOURNAL

The Auto-Inhibitory Role of the EPAC Hinge Helix as Mapped by NMR

(2012) Rajeevan Selvaratnam et al.   PLoS One

Role of Dynamics in the Autoinhibition and Activation of the Exchange Protein Directly Activated by Cyclic AMP (EPAC)

(2011) Bryan VanSchouwen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The statistical theory of allostery

(2011) Michele Vendruscolo   Nature Chemical Biology

Mapping allostery through the covariance analysis of NMR chemical shifts

(2011) R. Selvaratnam et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Heat shock protein 70 kDa chaperone/DnaJ cochaperone complex employs an unusual dynamic interface

(2011) A. Ahmad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Allosteric signal transmission in the nucleotide-binding domain of 70-kDa heat shock protein (Hsp70) molecular chaperones

(2011) A. Zhuravleva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic Allostery: Linkers Are Not Merely Flexible

(2011) Buyong Ma et al.   STRUCTURE

Communication between Tandem cAMP Binding Domains in the Regulatory Subunit of Protein Kinase A-Iα as Revealed by Domain-silencing Mutations

(2010) E. Tyler McNicholl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cyclic AMP- and (Rp)-cAMPS-induced Conformational Changes in a Complex of the Catalytic and Regulatory (RIα) Subunits of Cyclic AMP-dependent Protein Kinase

(2010) Ganesh S. Anand et al.   MOLECULAR & CELLULAR PROTEOMICS

Structural basis for regulation of the Crk signaling protein by a proline switch

(2010) Paramita Sarkar et al.   Nature Chemical Biology

Dynamically Driven Ligand Selectivity in Cyclic Nucleotide Binding Domains

(2009) Rahul Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of dynamic conformational ensembles in biomolecular recognition

(2009) David D Boehr et al.   Nature Chemical Biology

Sending Signals Dynamically

(2009) R. G. Smock et al.   SCIENCE

Entropy-driven cAMP-dependent Allosteric Control of Inhibitory Interactions in Exchange Proteins Directly Activated by cAMP

(2008) Rahul Das et al.   JOURNAL OF BIOLOGICAL CHEMISTRY