Do age-related changes in DNA methylation play a role in the development of age-related diseases?

Nutritional factors and gender influence age-related DNA methylation in the human rectal mucosa

(2012) Henri S. Tapp et al.   AGING CELL

Epigenetic variation during the adult lifespan: cross-sectional and longitudinal data on monozygotic twin pairs

(2012) Rudolf P. Talens et al.   AGING CELL

HACE1 Is a Tumor Suppressor Gene Candidate in Natural Killer Cell Neoplasms

(2012) Can Küçük et al.   AMERICAN JOURNAL OF PATHOLOGY

Study of methylation of histone H3 lysine 9 and H3 lysine 27 during X chromosome inactivation in three types of cells

(2012) Yan Li et al.   CHROMOSOME RESEARCH

Promoter methylation in coagulationF7gene influences plasma FVII concentrations and relates to coronary artery disease

(2012) Simonetta Friso et al.   JOURNAL OF MEDICAL GENETICS

450K-array analysis of chronic lymphocytic leukemia cells reveals global DNA methylation to be relatively stable over time and similar in resting and proliferative compartments

(2012) N Cahill et al.   LEUKEMIA

Cardiovascular epigenetics: From DNA methylation to microRNAs

(2012) Silvia Udali et al.   MOLECULAR ASPECTS OF MEDICINE

DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells

(2012) Christoph Bock et al.   MOLECULAR CELL

Epigenetic mechanisms in neurological disease

(2012) Mira Jakovcevski et al.   NATURE MEDICINE

MAGEB2 is Activated by Promoter Demethylation in Head and Neck Squamous Cell Carcinoma

(2012) Kavita M. Pattani et al.   PLoS One

BRCA1-methylated sporadic breast cancers are BRCA-like in showing a basal phenotype and absence of ER expression

(2012) Amanjit Bal et al.   VIRCHOWS ARCHIV

Genomic Imprinting and Epigenetic Control of Development

(2012) A. Fedoriw et al.   Cold Spring Harbor Perspectives in Biology

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(2012) Jordana T. Bell et al.   PLoS Genetics

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns

(2012) Duncan Sproul et al.   GENOME BIOLOGY

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

(2012) Matthew N Davies et al.   GENOME BIOLOGY

Global DNA methylation in old subjects is correlated with frailty

(2011) Dina Bellizzi et al.   AGE

Targeted Methylation of Two Tumor Suppressor Genes Is Sufficient to Transform Mesenchymal Stem Cells into Cancer Stem/Initiating Cells

(2011) I.-W. Teng et al.   CANCER RESEARCH

Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity

(2011) S. H. Thathia et al.   HAEMATOLOGICA

Evidence of constitutional MLH1 epimutation associated to transgenerational inheritance of cancer susceptibility

(2011) Michel Crépin et al.   HUMAN MUTATION

Increased methylation variation in epigenetic domains across cancer types

(2011) Kasper Daniel Hansen et al.   NATURE GENETICS

Epigenetic priming of the metabolic syndrome

(2011) Kimberley D Bruce et al.   TOXICOLOGY MECHANISMS AND METHODS

Tissue-specific dysregulation of DNA methylation in aging

(2010) Reid F. Thompson et al.   AGING CELL

Age-dependent DNA methylation of genes that are suppressed in stem cells is a hallmark of cancer

(2010) A. E. Teschendorff et al.   GENOME RESEARCH

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

(2010) V. K. Rakyan et al.   GENOME RESEARCH

Widespread and tissue specific age-related DNA methylation changes in mice

(2010) S. Maegawa et al.   GENOME RESEARCH

Predictors of global methylation levels in blood DNA of healthy subjects: a combined analysis

(2010) Zhong-Zheng Zhu et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Progressive age-dependent DNA methylation changes start before adulthood in mouse tissues

(2010) Masaki Takasugi   MECHANISMS OF AGEING AND DEVELOPMENT

Biodemography of human ageing

(2010) James W. Vaupel   NATURE

Distinctive patterns of age-dependent hypomethylation in interspersed repetitive sequences

(2010) Pornrutsami Jintaridth et al.   PHYSIOLOGICAL GENOMICS

Differential DNA Methylation Correlates with Differential Expression of Angiogenic Factors in Human Heart Failure

(2010) Mehregan Movassagh et al.   PLoS One

The Role of Epigenetics in Aging and Autoimmunity

(2009) Annabelle Grolleau-Julius et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Ageing populations: the challenges ahead

(2009) Kaare Christensen et al.   LANCET

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores

(2009) Rafael A Irizarry et al.   NATURE GENETICS

DNA methylation profiles in monozygotic and dizygotic twins

(2009) Zachary A Kaminsky et al.   NATURE GENETICS

Ovarian carcinomas with genetic and epigenetic BRCA1 loss have distinct molecular abnormalities

(2008) Joshua Z Press et al.   BMC CANCER

Profiling CpG island field methylation in both morphologically normal and neoplastic human colonic mucosa

(2008) N J Belshaw et al.   BRITISH JOURNAL OF CANCER

Decline in genomic DNA methylation through aging in a cohort of elderly subjects

(2008) Valentina Bollati et al.   MECHANISMS OF AGEING AND DEVELOPMENT