Argonaute and GW182 proteins: an effective alliance in gene silencing

Turning catalytically inactive human Argonaute proteins into active slicer enzymes

(2013) Judith Hauptmann et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Eukaryotic Argonautes come into focus

(2013) Claus-D. Kuhn et al.   TRENDS IN BIOCHEMICAL SCIENCES

The Structure of Human Argonaute-2 in Complex with miR-20a

(2012) Elad Elkayam et al.   CELL

Structure of yeast Argonaute with guide RNA

(2012) Kotaro Nakanishi et al.   NATURE

Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes

(2012) Derrick Gibbings et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A direct interaction between DCP1 and XRN1 couples mRNA decapping to 5′ exonucleolytic degradation

(2012) Joerg E Braun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The Crystal Structure of Human Argonaute2

(2012) N. T. Schirle et al.   SCIENCE

Agos--a universal web tool for GW Argonaute-binding domain prediction

(2011) A. Zielezinski et al.   BIOINFORMATICS

The structural basis of Edc3- and Scd6-mediated activation of the Dcp1:Dcp2 mRNA decapping complex

(2011) Simon A Fromm et al.   EMBO JOURNAL

GW182 Proteins Directly Recruit Cytoplasmic Deadenylase Complexes to miRNA Targets

(2011) Joerg E. Braun et al.   MOLECULAR CELL

Gene silencing by microRNAs: contributions of translational repression and mRNA decay

(2011) Eric Huntzinger et al.   NATURE REVIEWS GENETICS

PIWI-interacting small RNAs: the vanguard of genome defence

(2011) Mikiko C. Siomi et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

miRNA-mediated deadenylation is orchestrated by GW182 through two conserved motifs that interact with CCR4–NOT

(2011) Marc R Fabian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

miRNA repression involves GW182-mediated recruitment of CCR4–NOT through conserved W-containing motifs

(2011) Marina Chekulaeva et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Argonaute quenching and global changes in Dicer homeostasis caused by a pathogen-encoded GW repeat protein

(2010) J. Azevedo et al.   GENES & DEVELOPMENT

Argonaute proteins at a glance

(2010) C. Ender et al.   JOURNAL OF CELL SCIENCE

Structural basis for 5′-nucleotide base-specific recognition of guide RNA by human AGO2

(2010) Filipp Frank et al.   NATURE

Viral Protein Inhibits RISC Activity by Argonaute Binding through Conserved WG/GW Motifs

(2010) Ana Giner et al.   PLoS Pathogens

An Effector of RNA-Directed DNA Methylation in Arabidopsis Is an ARGONAUTE 4- and RNA-Binding Protein

(2009) Xin-Jian He et al.   CELL

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

Ubiquitin-like and ubiquitin-associated domain proteins: significance in proteasomal degradation

(2009) Vivian Su et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional Dissection of the Human TNRC6 (GW182-Related) Family of Proteins

(2009) D. Baillat et al.   MOLECULAR AND CELLULAR BIOLOGY

Two GW Repeat Proteins Interact with Tetrahymena thermophila Argonaute and Promote Genome Rearrangement

(2009) J. Bednenko et al.   MOLECULAR AND CELLULAR BIOLOGY

Mammalian miRNA RISC Recruits CAF1 and PABP to Affect PABP-Dependent Deadenylation

(2009) Marc R. Fabian et al.   MOLECULAR CELL

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

The RRM domain in GW182 proteins contributes to miRNA-mediated gene silencing

(2009) Ana Eulalio et al.   NUCLEIC ACIDS RESEARCH

Mammalian GW182 contains multiple Argonaute-binding sites and functions in microRNA-mediated translational repression

(2009) K. Takimoto et al.   RNA

The C-terminal half of human Ago2 binds to multiple GW-rich regions of GW182 and requires GW182 to mediate silencing

(2009) S. L. Lian et al.   RNA

A C-terminal silencing domain in GW182 is essential for miRNA function

(2009) A. Eulalio et al.   RNA

The C-terminal domains of human TNRC6A, TNRC6B, and TNRC6C silence bound transcripts independently of Argonaute proteins

(2009) D. Lazzaretti et al.   RNA

RNA recognition motifs: boring? Not quite

(2008) Antoine Cléry et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Understanding eukaryotic linear motifs and their role in cell signaling and regulation

(2008) Francesca Diella   Frontiers in Bioscience-Landmark

Argonaute proteins: key players in RNA silencing

(2007) Gyorgy Hutvagner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY