The multifunctional RNase XRN2

Microprocessor, Setx, Xrn2, and Rrp6 Co-operate to Induce Premature Termination of Transcription by RNAPII

(2012) Alexandre Wagschal et al.   CELL

Co-transcriptional degradation of aberrant pre-mRNA by Xrn2

(2012) Lee Davidson et al.   EMBO JOURNAL

A Tetrahymena Piwi Bound to Mature tRNA 3′ Fragments Activates the Exonuclease Xrn2 for RNA Processing in the Nucleus

(2012) Mary T. Couvillion et al.   MOLECULAR CELL

mRNA Decapping Factors and the Exonuclease Xrn2 Function in Widespread Premature Termination of RNA Polymerase II Transcription

(2012) Kris Brannan et al.   MOLECULAR CELL

MicroRNA turnover: when, how, and why

(2012) Stefan Rüegger et al.   TRENDS IN BIOCHEMICAL SCIENCES

Target-Mediated Protection of Endogenous MicroRNAs in C. elegans

(2011) Saibal Chatterjee et al.   DEVELOPMENTAL CELL

A cluster of ribosome synthesis factors regulate pre-rRNA folding and 5.8S rRNA maturation by the Rat1 exonuclease

(2011) Sander Granneman et al.   EMBO JOURNAL

Biogenic mechanisms and utilization of small RNAs derived from human protein-coding genes

(2011) Eivind Valen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Non-targeting siRNA induces NPGPx expression to cooperate with exoribonuclease XRN2 for releasing the stress

(2011) P.-C. Wei et al.   NUCLEIC ACIDS RESEARCH

The Yeast 5′-3′ Exonuclease Rat1p Functions during Transcription Elongation by RNA Polymerase II

(2010) Silvia Jimeno-González et al.   MOLECULAR CELL

In Brief

(2010)   NATURE REVIEWS GENETICS

5′-end surveillance by Xrn2 acts as a shared mechanism for mammalian pre-rRNA maturation and decay

(2010) Minshi Wang et al.   NUCLEIC ACIDS RESEARCH

Arabidopsis thaliana XRN2 is required for primary cleavage in the pre-ribosomal RNA

(2010) Monika Zakrzewska-Placzek et al.   NUCLEIC ACIDS RESEARCH

Differential regulation of microRNA stability

(2010) S. Bail et al.   RNA

TorpedoNuclease Rat1 Is Insufficient to Terminate RNA Polymerase IIin Vitro

(2009) Stefan Dengl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coupled RNA Processing and Transcription of Intergenic Primary MicroRNAs

(2009) M. Ballarino et al.   MOLECULAR AND CELLULAR BIOLOGY

Rrp17p Is a Eukaryotic Exonuclease Required for 5′ End Processing of Pre-60S Ribosomal RNA

(2009) Marlene Oeffinger et al.   MOLECULAR CELL

Active turnover modulates mature microRNA activity in Caenorhabditis elegans

(2009) Saibal Chatterjee et al.   NATURE

Structure and function of the 5′→3′ exoribonuclease Rat1 and its activating partner Rai1

(2009) Song Xiang et al.   NATURE

Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor

(2009) Y Lu et al.   ONCOGENE

A Novel Tandem Reporter Quantifies RNA Polymerase II Termination in Mammalian Cells

(2009) Ayan Banerjee et al.   PLoS One

Degradation of several hypomodified mature tRNA species in Saccharomyces cerevisiae is mediated by Met22 and the 5'-3' exonucleases Rat1 and Xrn1

(2008) I. Chernyakov et al.   GENES & DEVELOPMENT

Efficient termination of transcription by RNA polymerase I requires the 5' exonuclease Rat1 in yeast

(2008) A. El Hage et al.   GENES & DEVELOPMENT

Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination

(2008) J. Kawauchi et al.   GENES & DEVELOPMENT

The Rat1p 5′ to 3′ Exonuclease Degrades Telomeric Repeat-Containing RNA and Promotes Telomere Elongation in Saccharomyces cerevisiae

(2008) Brian Luke et al.   MOLECULAR CELL

Divergent Transcription from Active Promoters

(2008) Amy C. Seila et al.   SCIENCE