Molecular basis of Charcot–Marie–Tooth type 2B disease

The Role of Autophagy in Parkinson's Disease

(2013) M. A. Lynch-Day et al.   Cold Spring Harbor Perspectives in Medicine

A Competitive Nucleotide Binding Inhibitor: In Vitro Characterization of Rab7 GTPase Inhibition

(2012) Jacob O. Agola et al.   ACS Chemical Biology

The functional analysis of the CHMP2B missense mutation associated with neurodegenerative diseases in the endo-lysosomal pathway

(2012) Jeong-Ho Han et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular basis of axonal dysfunction and traffic impairments in CMT

(2012) Benoit J. Gentil et al.   BRAIN RESEARCH BULLETIN

Neuronal ceroid lipofuscinosis protein CLN3 interacts with motor proteins and modifies location of late endosomal compartments

(2012) Kristiina Uusi-Rauva et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Psoromic Acid is a Selective and Covalent Rab-Prenylation Inhibitor Targeting Autoinhibited RabGGTase

(2012) Céline Deraeve et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity

(2012) T. Maurer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Charcot–Marie–Tooth disease and intracellular traffic

(2012) Cecilia Bucci et al.   PROGRESS IN NEUROBIOLOGY

Dynamics of Rab7b-Dependent Transport of Sorting Receptors

(2012) Cinzia Progida et al.   TRAFFIC

Neuronal Autophagy: A Housekeeper or a Fighter in Neuronal Cell Survival?

(2012) Jin-A Lee   Experimental Neurobiology

Following autophagy step by step

(2011) Tom Hansen et al.   BMC BIOLOGY

Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation

(2011) Christelle En Lin Chua et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Axonal Charcot–Marie–Tooth disease

(2011) Michael E. Shy et al.   CURRENT OPINION IN NEUROLOGY

Proteomics Approach to Identify the Interacting Partners of Cellular Prion Protein and Characterization of Rab7a Interaction in Neuronal Cells

(2011) Saima Zafar et al.   JOURNAL OF PROTEOME RESEARCH

CMT2B-associated Rab7 mutants inhibit neurite outgrowth

(2010) Laura Cogli et al.   ACTA NEUROPATHOLOGICA

Microarray Analysis of Hippocampal CA1 Neurons Implicates Early Endosomal Dysfunction During Alzheimer's Disease Progression

(2010) Stephen D. Ginsberg et al.   BIOLOGICAL PSYCHIATRY

Rab7b controls trafficking from endosomes to the TGN

(2010) C. Progida et al.   JOURNAL OF CELL SCIENCE

Synthesis, Chiral High Performance Liquid Chromatographic Resolution and Enantiospecific Activity of a Potent New Geranylgeranyl Transferase Inhibitor, 2-Hydroxy-3-imidazo[1,2-a]pyridin-3-yl-2-phosphonopropionic Acid

(2010) Charles E. McKenna et al.   JOURNAL OF MEDICINAL CHEMISTRY

The mood stabilizer valproic acid improves defective neurite formation caused by charcot-marie-tooth disease-associated mutant Rab7 through the JNK signaling pathway

(2010) Junji Yamauchi et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Rab GTPases-Dependent Endocytic Pathways Regulate Neuronal Migration and Maturation through N-Cadherin Trafficking

(2010) Takeshi Kawauchi et al.   NEURON

IGF-I stimulates Rab7-RILP interaction during neuronal autophagy

(2010) Mona Bains et al.   NEUROSCIENCE LETTERS

Rab7 Mutants Associated with Charcot-Marie-Tooth Disease Exhibit Enhanced NGF-Stimulated Signaling

(2010) Soumik BasuRay et al.   PLoS One

Rab GTPases implicated in inherited and acquired disorders

(2010) Shreya Mitra et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Rab7 and the CMT2B disease

(2009) Laura Cogli et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

(2009) Zhenyu Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Disease mutations in Rab7 result in unregulated nucleotide exchange and inappropriate activation

(2009) Brett A. McCray et al.   HUMAN MOLECULAR GENETICS

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Characterization of the Rab7K157N mutant protein associated with Charcot–Marie-Tooth type 2B

(2008) Azzurra De Luca et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Functional Characterization of Rab7 Mutant Proteins Associated with Charcot-Marie-Tooth Type 2B Disease

(2008) M. R. Spinosa et al.   JOURNAL OF NEUROSCIENCE

Autophagy Induction and Autophagosome Clearance in Neurons: Relationship to Autophagic Pathology in Alzheimer's Disease

(2008) B. Boland et al.   JOURNAL OF NEUROSCIENCE

Cholesterol Loss Enhances TrkB Signaling in Hippocampal Neurons Aging in Vitro

(2008) Mauricio G. Martin et al.   MOLECULAR BIOLOGY OF THE CELL