Angiogenesis regulation by TGFβ signalling: clues from an inherited vascular disease

Alternative splicing factor or splicing factor-2 plays a key role in intron retention of the endoglin gene during endothelial senescence

(2011) Francisco J. Blanco et al.   AGING CELL

Interaction between alk1 and blood flow in the development of arteriovenous malformations

(2011) P. Corti et al.   DEVELOPMENT

Plasma endoglin as a marker to predict cardiovascular events in patients with chronic coronary artery diseases

(2011) Tomokazu Ikemoto et al.   HEART AND VESSELS

Soluble Endoglin Specifically Binds Bone Morphogenetic Proteins 9 and 10 via Its Orphan Domain, Inhibits Blood Vessel Formation, and Suppresses Tumor Growth

(2011) Roselyne Castonguay et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of betaglycan zona pellucida (ZP)-C domain provides insights into ZP-mediated protein polymerization and TGF-  binding

(2011) S. J. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The physiological role of endoglin in the cardiovascular system

(2010) José M. López-Novoa et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Arteriovenous malformation in the adult mouse brain resembling the human disease

(2010) Espen J. Walker et al.   ANNALS OF NEUROLOGY

Hereditary haemorrhagic telangiectasia: Pathophysiology, diagnosis and treatment

(2010) Claire L. Shovlin   BLOOD REVIEWS

Matrix Metalloproteinase-14 (MT1-MMP)-Mediated Endoglin Shedding Inhibits Tumor Angiogenesis

(2010) L. J. A. C. Hawinkels et al.   CANCER RESEARCH

Pathogenesis of Arteriovenous Malformations in the Absence of Endoglin

(2010) Marwa Mahmoud et al.   CIRCULATION RESEARCH

Genetic and pharmacological targeting of activin receptor-like kinase 1 impairs tumor growth and angiogenesis

(2010) Sara I. Cunha et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thalidomide stimulates vessel maturation and reduces epistaxis in individuals with hereditary hemorrhagic telangiectasia

(2010) Franck Lebrin et al.   NATURE MEDICINE

Application of Gene Network Analysis Techniques Identifies AXIN1/PDIA2 and Endoglin Haplotypes Associated with Bicuspid Aortic Valve

(2010) Eric C. Wooten et al.   PLoS One

Signaling by members of the TGF-β family in vascular morphogenesis and disease

(2010) Evangelia Pardali et al.   TRENDS IN CELL BIOLOGY

Endoglin-Targeted Cancer Therapy

(2010) Ben K. Seon et al.   Current Drug Delivery

ALK1 signaling regulates early postnatal lymphatic vessel development

(2009) K. Niessen et al.   BLOOD

ALK5 phosphorylation of the endoglin cytoplasmic domain regulates Smad1/5/8 signaling and endothelial cell migration

(2009) Bridgette N. Ray et al.   CARCINOGENESIS

Endoglin is dispensable for angiogenesis, but required for endocardial cushion formation in the midgestation mouse embryo

(2009) Aya Nomura-Kitabayashi et al.   DEVELOPMENTAL BIOLOGY

TGF-β Superfamily Signaling in Embryonic Development and Homeostasis

(2009) Mary Y. Wu et al.   DEVELOPMENTAL CELL

Bone Morphogenetic Protein (BMP) and Activin Type II Receptors Balance BMP9 Signals Mediated by Activin Receptor-like Kinase-1 in Human Pulmonary Artery Endothelial Cells

(2009) Paul D. Upton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S-Endoglin Expression Is Induced in Senescent Endothelial Cells and Contributes to Vascular Pathology

(2008) Francisco J. Blanco et al.   CIRCULATION RESEARCH

Endoglin Promotes Transforming Growth Factor β-mediated Smad 1/5/8 Signaling and Inhibits Endothelial Cell Migration through Its Association with GIPC

(2008) Nam Y. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ALK1 Opposes ALK5/Smad3 Signaling and Expression of Extracellular Matrix Components in Human Chondrocytes

(2008) Kenneth W Finnson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Endoglin and activin receptor-like-kinase 1 are co-expressed in the distal vessels of the lung: implications for two familial vascular dysplasias, HHT and PAH

(2008) Marwa Mahmoud et al.   LABORATORY INVESTIGATION