Using yeast models to probe the molecular basis of amyotrophic lateral sclerosis

Metabolic alterations in yeast lacking copper–zinc superoxide dismutase

(2011) Sadaf Sehati et al.   FREE RADICAL BIOLOGY AND MEDICINE

Ataxin-2 intermediate-length polyglutamine expansions in European ALS patients

(2011) T. Lee et al.   HUMAN MOLECULAR GENETICS

Neurotoxic 43-kDa TAR DNA-binding Protein (TDP-43) Triggers Mitochondrion-dependent Programmed Cell Death in Yeast

(2011) Ralf J. Braun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Yeast Model of FUS/TLS-Dependent Cytotoxicity

(2011) Shulin Ju et al.   PLOS BIOLOGY

FUS/TLS forms cytoplasmic aggregates, inhibits cell growth and interacts with TDP-43 in a yeast model of amyotrophic lateral sclerosis

(2011) Dmitry Kryndushkin et al.   Protein & Cell

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy

(2011) Kazuo Fushimi et al.   Protein & Cell

Roles of zinc and copper in modulating the oxidative refolding of bovine copper, zinc superoxide dismutase

(2010) H.-T. Li et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

In yeast redistribution of Sod1 to the mitochondrial intermembrane space provides protection against respiration derived oxidative stress

(2010) Christine Klöppel et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Yeast as a model for studying Alzheimer's disease

(2010) Prashant Bharadwaj et al.   FEMS YEAST RESEARCH

Glutaredoxin 2 prevents aggregation of mutant SOD1 in mitochondria and abolishes its toxicity

(2010) Alberto Ferri et al.   HUMAN MOLECULAR GENETICS

ALS-linked mutant SOD1 damages mitochondria by promoting conformational changes in Bcl-2

(2010) Steve Pedrini et al.   HUMAN MOLECULAR GENETICS

Ataxin-2 intermediate-length polyglutamine expansions are associated with increased risk for ALS

(2010) Andrew C. Elden et al.   NATURE

Requirement of glutathione for Sod1 activation during lifespan extension

(2010) Sérgio C. Mannarino et al.   YEAST

Yeast unfolds the road map toward α-synuclein-induced cell death

(2009) V Franssens et al.   CELL DEATH AND DIFFERENTIATION

The Human G93A-Superoxide Dismutase-1 Mutation, Mitochondrial Glutathione and Apoptotic Cell Death

(2009) H. Muyderman et al.   NEUROCHEMICAL RESEARCH

Protein folding diseases and neurodegeneration: Lessons learned from yeast

(2008) Joris Winderickx et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Different regulation of wild-type and mutant Cu,Zn superoxide dismutase localization in mammalian mitochondria

(2008) Hibiki Kawamata et al.   HUMAN MOLECULAR GENETICS

The Disulfide Relay System of Mitochondria Is Required for the Biogenesis of Mitochondrial Ccs1 and Sod1

(2008) Silvia Reddehase et al.   JOURNAL OF MOLECULAR BIOLOGY

Riluzole Increases the Amount of Latent HSF1 for an Amplified Heat Shock Response and Cytoprotection

(2008) Jingxian Yang et al.   PLoS One

A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity

(2008) B. S. Johnson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA