Autophagy Protects against Colitis by the Maintenance of Normal Gut Microflora and Secretion of Mucus

Bacteria from Diverse Habitats Colonize and Compete in the Mouse Gut

(2014) Henning Seedorf et al.   CELL

NLRP6 Inflammasome Orchestrates the Colonic Host-Microbial Interface by Regulating Goblet Cell Mucus Secretion

(2014) Marta Wlodarska et al.   CELL

Goblet Cell-Derived Resistin-Like Molecule   Augments CD4+ T Cell Production of IFN-  and Infection-Induced Intestinal Inflammation

(2014) M. G. Nair et al.   JOURNAL OF IMMUNOLOGY

A Crohn’s disease variant in Atg16l1 enhances its degradation by caspase 3

(2014) Aditya Murthy et al.   NATURE

Crohn's Disease–Associated Adherent Invasive Escherichia coli Modulate Levels of microRNAs in Intestinal Epithelial Cells to Reduce Autophagy

(2013) Hang Thi Thu Nguyen et al.   GASTROENTEROLOGY

IL-22 Deficiency Alters Colonic Microbiota To Be Transmissible and Colitogenic

(2013) L. A. Zenewicz et al.   JOURNAL OF IMMUNOLOGY

Autophagy in the intestinal epithelium regulates Citrobacter rodentium infection

(2012) Jun Inoue et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The FAP motif within human ATG7, an autophagy-related E1-like enzyme, is essential for the E2-substrate reaction of LC3 lipidation

(2012) Isei Tanida et al.   Autophagy

Autophagy in the intestinal epithelium is not involved in the pathogenesis of intestinal tumors

(2012) Shin Nishiumi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Lack of Intestinal Epithelial Atg7 Affects Paneth Cell Granule Formation but Does Not Compromise Immune Homeostasis in the Gut

(2012) Nadine Wittkopf et al.   Clinical & Developmental Immunology

Crohn's disease

(2012) Daniel C Baumgart et al.   LANCET

The keystone-pathogen hypothesis

(2012) George Hajishengallis et al.   NATURE REVIEWS MICROBIOLOGY

The Goblet Cell Is the Cellular Source of the Anti-Microbial Angiogenin 4 in the Large Intestine Post Trichuris muris Infection

(2012) Ruth A. Forman et al.   PLoS One

NLRP6 Inflammasome Regulates Colonic Microbial Ecology and Risk for Colitis

(2011) Eran Elinav et al.   CELL

Integrative analysis of environmental sequences using MEGAN4

(2011) D. H. Huson et al.   GENOME RESEARCH

Guidelines for the management of inflammatory bowel disease in adults

(2011) C. Mowat et al.   GUT

Impact of Probiotics on Colonizing Microbiota of the Gut

(2011) Mary Ellen Sanders   JOURNAL OF CLINICAL GASTROENTEROLOGY

Loss of intestinal core 1–derived O-glycans causes spontaneous colitis in mice

(2011) Jianxin Fu et al.   JOURNAL OF CLINICAL INVESTIGATION

Depletion of Murine Intestinal Microbiota: Effects on Gut Mucosa and Epithelial Gene Expression

(2011) Dag Henrik Reikvam et al.   PLoS One

Inflammatory Bowel Disease

(2010) Arthur Kaser et al.   Annual Review of Immunology

Autophagy in the intestinal epithelium reduces endotoxin-induced inflammatory responses by inhibiting NF-κB activation

(2010) Yoshimi Fujishima et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Milk sialyllactose influences colitis in mice through selective intestinal bacterial colonization

(2010) Andrea Fuhrer et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conditional Bicistronic Cre Reporter Line Expressing Both Firefly Luciferase and β-galactosidase

(2010) Tomo-o Ishikawa et al.   MOLECULAR IMAGING AND BIOLOGY

Sensing the outside world: TSLP regulates barrier immunity

(2010) Steven F Ziegler et al.   NATURE IMMUNOLOGY

Gastric acid reduction leads to an alteration in lower intestinal microflora

(2009) Takayuki Kanno et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Crohn's disease-associated adherent-invasiveE. coliare selectively favoured by impaired autophagy to replicate intracellularly

(2009) Pierre Lapaquette et al.   CELLULAR MICROBIOLOGY

Protein quality control during aging involves recruitment of the macroautophagy pathway by BAG3

(2009) Martin Gamerdinger et al.   EMBO JOURNAL

Capture of heat-killed Mycobacterium bovis bacillus Calmette-Guerin by intelectin-1 deposited on cell surfaces

(2009) S. Tsuji et al.   GLYCOBIOLOGY

Welcome to the neighborhood: epithelial cell-derived cytokines license innate and adaptive immune responses at mucosal sites

(2009) Steven A. Saenz et al.   IMMUNOLOGICAL REVIEWS

Sulfation of Colonic Mucins byN-Acetylglucosamine 6-O-Sulfotransferase-2 and Its Protective Function in Experimental Colitis in Mice

(2009) Yuki Tobisawa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intestinal epithelial cell secretion of RELM-β protects against gastrointestinal worm infection

(2009) De'Broski R. Herbert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Conditional Gene Targeting in Mouse High Endothelial Venules

(2009) H. Kawashima et al.   JOURNAL OF IMMUNOLOGY

IL-9 Promotes IL-13-Dependent Paneth Cell Hyperplasia and Up-Regulation of Innate Immunity Mediators in Intestinal Mucosa

(2009) V. Steenwinckel et al.   JOURNAL OF IMMUNOLOGY

Inflammatory Bowel Disease

(2009) Clara Abraham et al.   NEW ENGLAND JOURNAL OF MEDICINE

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

(2008) Hye Seung Jung et al.   Cell Metabolism

Distinct Cytokine Patterns Identified from Multiplex Profiles of Murine DSS and TNBS-Induced Colitis

(2008) Philip Alex et al.   INFLAMMATORY BOWEL DISEASES

Commensal-dependent expression of IL-25 regulates the IL-23–IL-17 axis in the intestine

(2008) Colby Zaph et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells

(2008) Ken Cadwell et al.   NATURE

Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

(2008) Tatsuya Saitoh et al.   NATURE

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

(2008) Jeffrey C Barrett et al.   NATURE GENETICS

Impaired Autophagy of an Intracellular Pathogen Induced by a Crohn's Disease Associated ATG16L1 Variant

(2008) Petric Kuballa et al.   PLoS One

The inner of the two Muc2 mucin-dependent mucus layers in colon is devoid of bacteria

(2008) M. E. V. Johansson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA