High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner

pH-induced conformational changes in human ABO(H) blood group glycosyltransferases confirm the importance of electrostatic interactions in the formation of the semi-closed state

(2013) A. R. Johal et al.   GLYCOBIOLOGY

Sequence-dependent effects of cryoprotectants on the active sites of the human ABO(H) blood group A and B glycosyltransferases

(2012) Asha R. Johal et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Binding of an acceptor substrate analog enhances the enzymatic activity of human blood group B galactosyltransferase

(2010) Nora Sindhuwinata et al.   GLYCOBIOLOGY

NMR-based exploration of the acceptor binding site of human blood group B galactosyltransferase with molecular fragments

(2010) Christoph Rademacher et al.   GLYCOCONJUGATE JOURNAL

Cysteine-to-Serine Mutants Dramatically Reorder the Active Site of Human ABO(H) Blood Group B Glycosyltransferase without Affecting Activity: Structural Insights into Cooperative Substrate Binding

(2010) Brock Schuman et al.   JOURNAL OF MOLECULAR BIOLOGY

Chemoenzymatic Synthesis, Inhibition Studies, and X-ray Crystallographic Analysis of the Phosphono Analog of UDP-Galp as an Inhibitor and Mechanistic Probe for UDP-Galactopyranose Mutase

(2010) Sarathy Karunan Partha et al.   JOURNAL OF MOLECULAR BIOLOGY

Comparative study of substrate and product binding to the human ABO(H) blood group glycosyltransferases

(2009) Naoto Soya et al.   GLYCOBIOLOGY

Enzyme-catalyzed synthesis of isosteric phosphono-analogues of sugar nucleotides

(2008) Stephen A. Beaton et al.   CHEMICAL COMMUNICATIONS

Structural insights into mechanism and specificity of O-GlcNAc transferase

(2008) Andrew J Clarke et al.   EMBO JOURNAL

ABO(H) Blood Group A and B Glycosyltransferases Recognize Substrate via Specific Conformational Changes

(2008) Javier A. Alfaro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY