Antioxidant Defenses ofFrancisella tularensisModulate Macrophage Function and Production of Proinflammatory Cytokines

Phenomenon of individual difference in human monocyte activation

(2015) Alexander N. Orekhov et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Differential Susceptibilities of Human Lung Primary Cells to H1N1 Influenza Viruses

(2015) Emily Travanty et al.   JOURNAL OF VIROLOGY

Vaccines against Tularemia

(2014) Eileen M. Barry et al.   Human vaccines & immunotherapeutics

EmrA1 membrane fusion protein ofFrancisella tularensis LVS is required for resistance to oxidative stress, intramacrophage survival and virulence in mice

(2014) Zhuo Ma et al.   MOLECULAR MICROBIOLOGY

Virulent Type A Francisella tularensis actively suppresses cytokine responses in human monocytes

(2014) Devyn D. Gillette et al.   Frontiers in Cellular and Infection Microbiology

TheFrancisellaO-antigen mediates survival in the macrophage cytosol via autophagy avoidance

(2013) Elizabeth Di Russo Case et al.   CELLULAR MICROBIOLOGY

FcγR-driven Release of IL-6 by Macrophages Requires NOX2-dependent Production of Reactive Oxygen Species

(2013) Anthony M. Franchini et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Live Attenuated Vaccine Candidate for Tularemia Prophylaxis

(2013) Manish Mahawar et al.   PLoS One

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Identification of a NovelFrancisella tularensisFactor Required for Intramacrophage Survival and Subversion of Innate Immune Response

(2012) Manish Mahawar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Extracellular Superoxide Dismutase Inhibits Innate Immune Responses and Clearance of an Intracellular Bacterial Infection

(2012) T. J. Break et al.   JOURNAL OF IMMUNOLOGY

Natural IgM Mediates Complement-Dependent Uptake of Francisella tularensis by Human Neutrophils via Complement Receptors 1 and 3 in Nonimmune Serum

(2012) J. T. Schwartz et al.   JOURNAL OF IMMUNOLOGY

Regulation of Anoxic Death in Caenorhabditis elegans by Mammalian Apoptosis Signal-Regulating Kinase (ASK) Family Proteins

(2011) T. Hayakawa et al.   GENETICS

Phagocytic Receptors Dictate Phagosomal Escape and Intracellular Proliferation of Francisella tularensis

(2011) Henriette Geier et al.   INFECTION AND IMMUNITY

Identification of a Putative Chaperone Involved in Stress Resistance and Virulence inFrancisella tularensis

(2011) Jennifer Dieppedale et al.   INFECTION AND IMMUNITY

TLR signalling augments macrophage bactericidal activity through mitochondrial ROS

(2011) A. Phillip West et al.   NATURE

Macrophage Replication Screen Identifies a Novel Francisella Hydroperoxide Resistance Protein Involved in Virulence

(2011) Anna C. Llewellyn et al.   PLoS One

Francisella Subverts Innate Immune Signaling: Focus On PI3K/Akt

(2011) Thomas John Cremer et al.   Frontiers in Microbiology

The Subversion of the Immune System by Francisella Tularensis

(2011) Catharine M. Bosio   Frontiers in Microbiology

Francisella tularensis  pyrF Mutants Show that Replication in Nonmacrophages Is Sufficient for Pathogenesis In Vivo

(2010) J. Horzempa et al.   INFECTION AND IMMUNITY

Francisella tularensisAntioxidants Harness Reactive Oxygen Species to Restrict Macrophage Signaling and Cytokine Production

(2010) Amanda A. Melillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Type I NADH Dehydrogenase of Mycobacterium tuberculosis Counters Phagosomal NOX2 Activity to Inhibit TNF-α-Mediated Host Cell Apoptosis

(2010) Jessica L. Miller et al.   PLoS Pathogens

Mycobacterium tuberculosis Eis Regulates Autophagy, Inflammation, and Cell Death through Redox-dependent Signaling

(2010) Dong-Min Shin et al.   PLoS Pathogens

Redox Control of the Cell Cycle in Health and Disease

(2009) Ehab H. Sarsour et al.   ANTIOXIDANTS & REDOX SIGNALING

MCP-1 causes cardiomyoblast death via autophagy resulting from ER stress caused by oxidative stress generated by inducing a novel zinc-finger protein, MCPIP

(2009) Craig W. Younce et al.   BIOCHEMICAL JOURNAL

Intracellular biology and virulence determinants ofFrancisella tularensisrevealed by transcriptional profiling inside macrophages

(2009) Tara D. Wehrly et al.   CELLULAR MICROBIOLOGY

Francisella tularensis Genes Required for Inhibition of the Neutrophil Respiratory Burst and Intramacrophage Growth Identified by Random Transposon Mutagenesis of Strain LVS

(2009) G. S. Schulert et al.   INFECTION AND IMMUNITY

Identification of Francisella tularensis Live Vaccine Strain CuZn Superoxide Dismutase as Critical for Resistance to Extracellularly Generated Reactive Oxygen Species

(2009) A. A. Melillo et al.   JOURNAL OF BACTERIOLOGY

Role of reactive oxygen species (ROS) in Mycobacterium bovis bacillus Calmette Guérin-mediated up-regulation of the human cathelicidin LL-37 in A549 cells

(2009) Patricia Méndez-Samperio et al.   MICROBIAL PATHOGENESIS

Working toward the Future: Insights into Francisella tularensis Pathogenesis and Vaccine Development

(2009) R. D. Pechous et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Reducing the Activity and Secretion of Microbial Antioxidants Enhances the Immunogenicity of BCG

(2009) Shanmugalakshmi Sadagopal et al.   PLoS One

Role of apoptosis-regulating signal kinase 1 in innate immune responses by Mycobacterium bovis bacillus Calmette-Guérin

(2008) Jae-Min Yuk et al.   IMMUNOLOGY AND CELL BIOLOGY

RipA, a Cytoplasmic Membrane Protein Conserved among Francisella Species, Is Required for Intracellular Survival

(2008) J. R. Fuller et al.   INFECTION AND IMMUNITY

Direct and Indirect Impairment of Human Dendritic Cell Function by Virulent Francisella tularensis Schu S4

(2008) J. C. Chase et al.   INFECTION AND IMMUNITY

Microarray Analysis of Human Monocytes Infected with Francisella tularensis Identifies New Targets of Host Response Subversion

(2008) Jonathan P. Butchar et al.   PLoS One

An improved vaccine for prevention of respiratory tularemia caused by Francisella tularensis SchuS4 strain

(2008) Chandra Shekhar Bakshi et al.   VACCINE

ASK1-p38 MAPK-p47phox activation is essential for inflammatory responses during tuberculosis via TLR2-ROS signalling

(2007) Chul-Su Yang et al.   CELLULAR MICROBIOLOGY