Critical Role of the Neonatal Fc Receptor (FcRn) in the Pathogenic Action of Antimitochondrial Autoantibodies Synergizing with Anti-desmoglein Autoantibodies in Pemphigus Vulgaris

Pemphigus vulgaris antibodies target the mitochondrial nicotinic acetylcholine receptors that protect keratinocytes from apoptolysis

(2015) Alex Chernyavsky et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Low pathogenicity of anti-desmoglein 3 immunoglobulin G autoantibodies contributes to the atypical clinical phenotypes in pemphigus

(2015) Marwah A. Saleh et al.   JOURNAL OF DERMATOLOGY

The Protein Import Machinery of Mitochondria—A Regulatory Hub in Metabolism, Stress, and Disease

(2014) Angelika B. Harbauer et al.   Cell Metabolism

Divergent outcomes following transcytosis of IgG targeting intracellular and extracellular chlamydial antigens

(2014) Charles W Armitage et al.   IMMUNOLOGY AND CELL BIOLOGY

Targeting FcRn for therapy: From live cell imaging to in vivo studies in mice

(2014) E. Sally Ward et al.   IMMUNOLOGY LETTERS

α7 nicotinic acetylcholine receptors control cytochrome c release from isolated mitochondria through kinase-mediated pathways

(2014) Galyna Gergalova et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Mitochondria express several nicotinic acetylcholine receptor subtypes to control various pathways of apoptosis induction

(2014) Olena Lykhmus et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Nanorobotic Investigation Identifies Novel Visual, Structural and Functional Correlates of Autoimmune Pathology in a Blistering Skin Disease Model

(2014) Kristina Seiffert-Sinha et al.   PLoS One

Novel markers of squamous differentiation in the urinary bladder

(2013) Wenbin Huang et al.   HUMAN PATHOLOGY

Mechanisms of Mitochondrial Damage in Keratinocytes by Pemphigus Vulgaris Antibodies

(2013) Mina Kalantari-Dehaghi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pemphigus Vulgaris Autoantibody Profiling by Proteomic Technique

(2013) Mina Kalantari-Dehaghi et al.   PLoS One

Analysis of the reactivity of indirect immunofluorescence in patients with pemphigus foliaceus and pemphigus vulgaris using rat bladder epithelium as a substrate

(2012) Damaris G. Ortolan et al.   Clinics

Inhibition of FAK prevents blister formation in the neonatal mouse model of pemphigus vulgaris

(2012) María P. Gil et al.   EXPERIMENTAL DERMATOLOGY

Constructing immunoprofiles to deconstruct disease complexity in pemphigus

(2011) Animesh A. Sinha   AUTOIMMUNITY

Pemphigus autoimmunity: Hypotheses and realities

(2011) Sergei A. Grando   AUTOIMMUNITY

Nek1 regulates cell death and mitochondrial membrane permeability through phosphorylation of VDAC1

(2011) Yumay Chen et al.   CELL CYCLE

Megalin/Cubilin-mediated Uptake of FITC-labeled IgG by OK Kidney Epithelial Cells

(2011) Junya Nagai et al.   Drug Metabolism and Pharmacokinetics

Urban legends: pemphigus vulgaris

(2011) N Cirillo et al.   ORAL DISEASES

Intracellular neutralization of viral infection in polarized epithelial cells by neonatal Fc receptor (FcRn)-mediated IgG transport

(2011) Y. Bai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Phosphorylation by Nek1 regulates opening and closing of voltage dependent anion channel 1

(2010) Yumay Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The neonatal Fc receptor as therapeutic target in IgG-mediated autoimmune diseases

(2010) Alina Sesarman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Homologous regions of autoantibody heavy chain complementarity-determining region 3 (H-CDR3) in patients with pemphigus cause pathogenicity

(2010) Jun Yamagami et al.   JOURNAL OF CLINICAL INVESTIGATION

What’s new in i.v. immunoglobulin therapy and pemphigus: High-dose i.v. immunoglobulin therapy and its mode of action for treatment of pemphigus

(2010) Yumi AOYAMA   JOURNAL OF DERMATOLOGY

Apoptolysis: a novel mechanism of skin blistering in pemphigus vulgaris linking the apoptotic pathways to basal cell shrinkage and suprabasal acantholysis

(2009) Sergei A. Grando et al.   EXPERIMENTAL DERMATOLOGY

Antimitochondrial Autoantibodies in Pemphigus Vulgaris

(2009) Steve Marchenko et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reversibility of apoptosis in cancer cells

(2008) H L Tang et al.   BRITISH JOURNAL OF CANCER

Neonatal Fc Receptor Mediates Internalization of Fc in Transfected Human Endothelial Cells

(2008) Nancy A. Goebl et al.   MOLECULAR BIOLOGY OF THE CELL