An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation

Molecular control of the NEMO family of ubiquitin-binding proteins

(2013) Kristopher Clark et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of the canonical IKK complex by K63/M1-linked hybrid ubiquitin chains

(2013) C. H. Emmerich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Structural Basis for IκB Kinase 2 Activation Via Oligomerization-Dependent Trans Auto-Phosphorylation

(2013) Smarajit Polley et al.   PLOS BIOLOGY

DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out

(2012) Kevin W. McCool et al.   IMMUNOLOGICAL REVIEWS

Essential Role for IKKβ in Production of Type 1 Interferons by Plasmacytoid Dendritic Cells

(2012) Eduardo Pauls et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Analysis of Nuclear Factor-κB (NF-κB) Essential Modulator (NEMO) Binding to Linear and Lysine-linked Ubiquitin Chains and Its Role in the Activation of NF-κB

(2012) Tobias Kensche et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Coordinate Regulation of TPL-2 and NF- B Signaling in Macrophages by NF- B1 p105

(2012) H.-T. Yang et al.   MOLECULAR AND CELLULAR BIOLOGY

Phosphorylation of CRTC3 by the salt-inducible kinases controls the interconversion of classically activated and regulatory macrophages

(2012) K. Clark et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel cross-talk within the IKK family controls innate immunity

(2011) Kristopher Clark et al.   BIOCHEMICAL JOURNAL

Polyubiquitin binding to ABIN1 is required to prevent autoimmunity

(2011) Sambit K. Nanda et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Specific Recognition of Linear Ubiquitin Chains by NEMO Is Important for NF-κB Activation

(2009) Simin Rahighi et al.   CELL

Structural Basis for Recognition of Diubiquitins by NEMO

(2009) Yu-Chih Lo et al.   MOLECULAR CELL

Direct activation of protein kinases by unanchored polyubiquitin chains

(2009) Zong-Ping Xia et al.   NATURE

Involvement of linear polyubiquitylation of NEMO in NF-κB activation

(2009) Fuminori Tokunaga et al.   NATURE CELL BIOLOGY