Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2
Published 2014 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2
Authors
Keywords
-
Journal
BIOCHEMICAL JOURNAL
Volume 459, Issue 1, Pages 193-203
Publisher
Portland Press Ltd.
Online
2014-01-21
DOI
10.1042/bj20130558
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Piperine activates human pregnane X receptor to induce the expression of cytochrome P450 3A4 and multidrug resistance protein 1
- (2013) Yue-Ming Wang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Role of CAR and PXR in xenobiotic sensing and metabolism
- (2012) Yue-Ming Wang et al. Expert Opinion on Drug Metabolism & Toxicology
- GUItars: A GUI Tool for Analysis of High-Throughput RNA Interference Screening Data
- (2012) Asli N. Goktug et al. PLoS One
- Post-translational modification of pregnane x receptor
- (2011) Jeff L. Staudinger et al. PHARMACOLOGICAL RESEARCH
- Flavonoids activate pregnane × receptor-mediated CYP3A4 gene expression by inhibiting cyclin-dependent kinases in HepG2 liver carcinoma cells
- (2010) Hanqing Dong et al. BMC BIOCHEMISTRY
- Pregnane X Receptor (PXR) expression in colorectal cancer cells restricts irinotecan chemosensitivity through enhanced SN-38 glucuronidation
- (2010) Caroline Raynal et al. Molecular Cancer
- WD40 proteins propel cellular networks
- (2010) Christian U. Stirnimann et al. TRENDS IN BIOCHEMICAL SCIENCES
- Induction of UGT1A1 and CYP2B6 by an Antimitogenic Factor in HepG2 Cells Is Mediated through Suppression of Cyclin-Dependent Kinase 2 Activity: Cell Cycle-Dependent Expression
- (2009) J. Sugatani et al. DRUG METABOLISM AND DISPOSITION
- A Phosphomimetic Mutation at Threonine-57 Abolishes Transactivation Activity and Alters Nuclear Localization Pattern of Human Pregnane X Receptor
- (2009) S. R. Pondugula et al. DRUG METABOLISM AND DISPOSITION
- Phosphorylation and protein–protein interactions in PXR-mediated CYP3A repression
- (2009) Satyanarayana R Pondugula et al. Expert Opinion on Drug Metabolism & Toxicology
- A Systematic Analysis of Predicted Phosphorylation Sites within the Human Pregnane X Receptor Protein
- (2009) K. Lichti-Kaiser et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase
- (2009) Subbareddy Maddika et al. NATURE CELL BIOLOGY
- The E3 ubiquitin ligase EDD is an adverse prognostic factor for serous epithelial ovarian cancer and modulates cisplatin resistance in vitro
- (2008) P M O'Brien et al. BRITISH JOURNAL OF CANCER
- Cyclin-dependent Kinase 2 Negatively Regulates Human Pregnane X Receptor-mediatedCYP3A4Gene Expression in HepG2 Liver Carcinoma Cells
- (2008) Wenwei Lin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation of UDP-glucuronosyltransferase (UGT) 1A1 by progesterone and its impact on labetalol elimination
- (2007) H. Jeong et al. XENOBIOTICA
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationPublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More