pVHL acts as a downstream target of E2F1 to suppress E2F1 activity

Transcriptional and Nontranscriptional Functions of E2F1 in Response to DNA Damage

(2011) A. K. Biswas et al.   CANCER RESEARCH

p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death

(2011) Xi Feng et al.   EMBO JOURNAL

Translating DNA damage into cancer cell death—A roadmap for E2F1 apoptotic signalling and opportunities for new drug combinations to overcome chemoresistance

(2010) David Engelmann et al.   DRUG RESISTANCE UPDATES

Lysine Methylation Regulates E2F1-Induced Cell Death

(2010) Haroula Kontaki et al.   MOLECULAR CELL

Hypoxia and cell cycle regulation of the von Hippel–Lindau tumor suppressor

(2010) W Liu et al.   ONCOGENE

E2F-1 Directly Regulates Thrombospondin 1 Expression

(2010) Wei Ji et al.   PLoS One

Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis

(2009) G. L. Semenza   BLOOD

Elongation Factor ELL (Eleven-Nineteen Lysine-rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation

(2009) Jiangang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

E2f1–3 switch from activators in progenitor cells to repressors in differentiating cells

(2009) Jean-Leon Chong et al.   NATURE

VHL loss actuates a HIF-independent senescence programme mediated by Rb and p400

(2008) Arthur P. Young et al.   NATURE CELL BIOLOGY

Conserved functions of the pRB and E2F families

(2008) Sander van den Heuvel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY