Identification of protein succination as a novel modification of tubulin

Regulation of microtubule motors by tubulin isotypes and post-translational modifications

(2014) Minhajuddin Sirajuddin et al.   NATURE CELL BIOLOGY

Adipocyte protein modification by Krebs cycle intermediates and fumarate ester-derived succination

(2013) Allison M. Manuel et al.   AMINO ACIDS

Dimethyl Fumarate for Treatment of Multiple Sclerosis: Mechanism of Action, Effectiveness, and Side Effects

(2013) Ralf A. Linker et al.   Current Neurology and Neuroscience Reports

The succinated proteome

(2013) Eric D. Merkley et al.   MASS SPECTROMETRY REVIEWS

Inhibition of Mitochondrial Aconitase by Succination in Fumarate Hydratase Deficiency

(2013) Nicola Ternette et al.   Cell Reports

Mitochondrial stress causes increased succination of proteins in adipocytes in response to glucotoxicity

(2012) Norma Frizzell et al.   BIOCHEMICAL JOURNAL

The chemical complexity of cellular microtubules: Tubulin post-translational modification enzymes and their roles in tuning microtubule functions

(2012) Christopher P. Garnham et al.   Cytoskeleton

Tianeptine modulates amygdalar glutamate neurochemistry and synaptic proteins in rats subjected to repeated stress

(2012) Gerardo G. Piroli et al.   EXPERIMENTAL NEUROLOGY

Proteomic Analysis of Covalent Modifications of Tubulins by Isothiocyanates

(2012) Zhen Xiao et al.   JOURNAL OF NUTRITION

Placebo-Controlled Phase 3 Study of Oral BG-12 or Glatiramer in Multiple Sclerosis

(2012) Robert J. Fox et al.   NEW ENGLAND JOURNAL OF MEDICINE

Fumaric acid esters exert neuroprotective effects in neuroinflammation via activation of the Nrf2 antioxidant pathway

(2011) Ralf A. Linker et al.   BRAIN

Fumaric acid and its esters: An emerging treatment for multiple sclerosis with antioxidative mechanism of action

(2011) R. Gold et al.   CLINICAL IMMUNOLOGY

Fumarates improve psoriasis and multiple sclerosis by inducing type II dendritic cells

(2011) Kamran Ghoreschi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Dimethylfumarate Inhibits Angiogenesis In Vitro and In Vivo: A Possible Role for Its Antipsoriatic Effect?

(2011) Melissa García-Caballero et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Post-translational regulation of the microtubule cytoskeleton: mechanisms and functions

(2011) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Tissue Distribution of S-(2-Succino)cysteine (2SC), a Biomarker of Mitochondrial Stress in Obesity and Diabetes

(2011) Sonia A. Thomas et al.   Obesity

The ins and outs of tubulin acetylation: More than just a post-translational modification?

(2010) Daniel Perdiz et al.   CELLULAR SIGNALLING

Site-Specific Protein Adducts of 4-Hydroxy-2(E)-Nonenal in Human THP-1 Monocytic Cells: Protein Carbonylation Is Diminished by Ascorbic Acid

(2010) Juan Chavez et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Succination of proteins in diabetes

(2010) Norma Frizzell et al.   FREE RADICAL RESEARCH

Fumaric acid diesters deprive cultured primary astrocytes rapidly of glutathione

(2010) Maike M. Schmidt et al.   NEUROCHEMISTRY INTERNATIONAL

Fumaric acid dialkyl esters deprive cultured rat oligodendroglial cells of glutathione and upregulate the expression of heme oxygenase 1

(2010) Anette Thiessen et al.   NEUROSCIENCE LETTERS

Acyl-biotinyl Exchange Chemistry and Mass Spectrometry-Based Analysis of Palmitoylation Sites of In Vitro Palmitoylated Rat Brain Tubulin

(2010) Zhiqiang Zhao et al.   PROTEIN JOURNAL

Dimethylfumarate inhibits tumor cell invasion and metastasis by suppressing the expression and activities of matrix metalloproteinases in melanoma cells

(2009) Yuzuru Yamazoe et al.   CELL BIOLOGY INTERNATIONAL

Succination of Thiol Groups in Adipose Tissue Proteins in Diabetes

(2009) Norma Frizzell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combination of Dacarbazine and Dimethylfumarate Efficiently Reduces Melanoma Lymph Node Metastasis

(2009) Teresa Valero et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Natural product derivative Bis(4-fluorobenzyl)trisulfide inhibits tumor growth by modification of  -tubulin at Cys 12 and suppression of microtubule dynamics

(2009) W. Xu et al.   MOLECULAR CANCER THERAPEUTICS

Polyglutamylation: a fine-regulator of protein function? ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Carsten Janke et al.   EMBO REPORTS