Phosphoproteomics of collagen receptor networks reveals SHP-2 phosphorylation downstream of wild-type DDR2 and its lung cancer mutants

Discoidin Domain Receptors: Unique Receptor Tyrosine Kinases in Collagen-mediated Signaling

(2013) Hsueh-Liang Fu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoproteomic analysis identifies insulin enhancement of discoidin domain receptor 2 phosphorylation

(2013) Leo K. Iwai et al.   Cell Adhesion & Migration

Discoidin domain receptor tyrosine kinases: new players in cancer progression

(2012) Rajeshwari R. Valiathan et al.   CANCER AND METASTASIS REVIEWS

Phosphoproteomics Identifies Driver Tyrosine Kinases in Sarcoma Cell Lines and Tumors

(2012) Y. Bai et al.   CANCER RESEARCH

Discoidin Domain Receptors Promote α1β1- and α2β1-Integrin Mediated Cell Adhesion to Collagen by Enhancing Integrin Activation

(2012) Huifang Xu et al.   PLoS One

Transmembrane Collagen Receptors

(2011) Birgit Leitinger   Annual Review of Cell and Developmental Biology

Differences in integrin expression and signaling within human breast cancer cells

(2011) Aliakbar Taherian et al.   BMC CANCER

Discoidin domain receptor 2 deficiency predisposes hepatic tissue to colon carcinoma metastasis

(2011) Iker Badiola et al.   GUT

Collagen I Induces Discoidin Domain Receptor (DDR) 1 Expression through DDR2 and a JAK2-ERK1/2-mediated Mechanism in Primary Human Lung Fibroblasts

(2011) Pedro A. Ruiz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoproteomic studies of receptor tyrosine kinases: future perspectives

(2011) Paul H. Huang   Molecular BioSystems

Fibroblast polarization is a matrix-rigidity-dependent process controlled by focal adhesion mechanosensing

(2011) Masha Prager-Khoutorsky et al.   NATURE CELL BIOLOGY

Survey of Tyrosine Kinase Signaling Reveals ROS Kinase Fusions in Human Cholangiocarcinoma

(2011) Ting-Lei Gu et al.   PLoS One

A HIF-Regulated VHL-PTP1B-Src Signaling Axis Identifies a Therapeutic Target in Renal Cell Carcinoma

(2011) N. Suwaki et al.   Science Translational Medicine

A New Target for Therapy in Squamous Cell Carcinoma of the Lung: Table 1.

(2011) Kadoaki Ohashi et al.   Cancer Discovery

Mutations in the DDR2 Kinase Gene Identify a Novel Therapeutic Target in Squamous Cell Lung Cancer

(2011) Peter S. Hammerman et al.   Cancer Discovery

MCAM: Multiple Clustering Analysis Methodology for Deriving Hypotheses and Insights from High-Throughput Proteomic Datasets

(2011) Kristen M. Naegle et al.   PLoS Computational Biology

Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice

(2010) Lin Xu et al.   ARTHRITIS AND RHEUMATISM

Dynamic interplay between the collagen scaffold and tumor evolution

(2010) Mikala Egeblad et al.   CURRENT OPINION IN CELL BIOLOGY

Collagen binding specificity of the discoidin domain receptors: Binding sites on collagens II and III and molecular determinants for collagen IV recognition by DDR1

(2010) Huifang Xu et al.   MATRIX BIOLOGY

PTMScout, a Web Resource for Analysis of High Throughput Post-translational Proteomics Studies

(2010) Kristen M. Naegle et al.   MOLECULAR & CELLULAR PROTEOMICS

EGFRvIV: a previously uncharacterized oncogenic mutant reveals a kinase autoinhibitory mechanism

(2010) G Pines et al.   ONCOGENE

Magnetic Bead Processor for Rapid Evaluation and Optimization of Parameters for Phosphopeptide Enrichment

(2009) Scott B. Ficarro et al.   ANALYTICAL CHEMISTRY

Hypoxia-Induced Lysyl Oxidase Is a Critical Mediator of Bone Marrow Cell Recruitment to Form the Premetastatic Niche

(2009) Janine T. Erler et al.   CANCER CELL

Combined Integrin Phosphoproteomic Analyses and Small Interfering RNA-Based Functional Screening Identify Key Regulators for Cancer Cell Adhesion and Migration

(2009) Y. Chen et al.   CANCER RESEARCH

Her4 and Her2/neu Tyrosine Kinase Domains Dimerize and Activate in a Reconstitutedin VitroSystem

(2009) John Monsey et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Discoidin domain receptor 2 mediates the collagen II-dependent release of interleukin-6 in primary human chondrocytes

(2009) Andreas R Klatt et al.   JOURNAL OF PATHOLOGY

Discoidin domain receptor 2 is associated with the increased expression of matrix metalloproteinase-13 in synovial fibroblasts of rheumatoid arthritis

(2009) Jin Su et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Proteomic Analysis of Integrin-Associated Complexes Identifies RCC2 as a Dual Regulator of Rac1 and Arf6

(2009) J. D. Humphries et al.   Science Signaling

Cell–collagen interactions: the use of peptide Toolkits to investigate collagen–receptor interactions

(2008) Richard W. Farndale et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Age-associated changes of extracellular matrix collagen impair lung cancer cell migration

(2008) Babett Bartling et al.   FASEB JOURNAL

Characterization of High Affinity Binding Motifs for the Discoidin Domain Receptor DDR2 in Collagen

(2008) Antonios D. Konitsiotis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY